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The genetic mechanism of Alzheimer's disease family in China has been revealed
Time of Update: 2021-01-04
"But 83.17 percent of the 404 family lineages do not carry the known gene PSENs/APP mutation, and there are still a number of unknown genes to be excavated, which will have an important impact on the discovery of Chinese AD's characteristic genes." Jia jianping said the team reported China's first FAD in 2005, which opened the way for genetic research into AD.
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Mosquito saliva protein aids the spread of the virus
Time of Update: 2021-01-04
Recently, Cheng Gong, a professor at Tsinghua University School of Medicine, found a Aedes aegypti saliva protein Aava-1, verified its mechanism to affect the spread of the virus, and provided a new intervention target for mosquito-borne virus prevention and control.
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There is a new strategy for treating disc degenerative diseases in the vertebral disc
Time of Update: 2021-01-04
Shen Hongxing, author of the paper, said that the proposal of "gene-hydrogel microencancer" not only provides a new way of thinking for the regeneration of the degenerative disc, but also provides a new theoretical basis and application platform for the treatment of various degenerative diseases, which has unique innovation and wide applicability.
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The study found that respiratory viruses evade the immune system
Time of Update: 2021-01-04
Researchers at Ohio State University in the United States, by tracking cell signals used to produce an inherent immune response, found that the "human pulmonary virus" after methylation modified, successfully reduced the immune protein's ability to recognize viral RNA, thus avoiding the immune system attack.
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Springer Nature New Coronavirus (SARS-CoV-2) Resource Center BMC-related content collection
Time of Update: 2021-01-04
to help China's multi-party response to the new coronavirus, and to provide reference for global prevention and control and policy development, journal editorial department is now on the relevant scope of draft.
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The data show that the human body may be cooling
Time of Update: 2021-01-04
team led by Julie Parsonnet, an infectious disease epidemiologist at Stanford University in the United States, estimates that the average body temperature of modern people is lower than the textbook 37 degrees Celsius and drops by a few degrees every 10 years.
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Bionic nanoparticles are expected to be a mucous membrane adjunct to the universal flu vaccine
Time of Update: 2021-01-04
Fudan University School of Basic Medicine and Jiang Shibo team, in collaboration with Associate Professor Mei X Wu of The Massachusetts General Hospital of Harvard Medical School, have revealed the role and mechanism of bionic nanoparticles as mucous membrane admissors for the universal influenza vaccine.
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The llama microantibodies can fight the new coronavirus
Time of Update: 2020-12-31
In a study published in Scientific Reports on December 22nd, researchers at the National Institutes of Health (NIH) said they had isolated a group of tiny antibodies, or nanoantibodies, from a llama named Cormac, promising to fight the new coronavirus.
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The immune micro-environment and tumor immune escape mechanism of early recurrence of liver cancer were solved
Time of Update: 2020-12-31
Fudan University (Zhongshan Hospital) Liver Cancer Research Institute, in collaboration with the Shenzhen Huada Institute of Life Sciences, using single-cell RNA sequencing technology, from the single-cell level revealed the early recurrence of liver cancer immune characteristics and tumor immune escape mechanism.
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Track the afterchio for 300 years
Time of Update: 2020-12-31
To better understand the history of the flux and its vaccines and to draw on the current global epidemic of neo-crown pneumonia, researchers at the Canadian Institute of Health Information and McMaster University studied and analyzed thousands of records that recorded weekly deaths of people with flux in London, England, over the past 300 years.
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Why autistic children are "unbalanced"
Time of Update: 2020-12-31
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder in which patients often exhibit social interaction, communication difficulties, repetitive and stereotyped behavior, and limited intere
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New antibiotics are effective against a wide range of bacteria
Time of Update: 2020-12-31
basic functions of existing antibiotic-targeted bacteria, including nucleic acid and protein synthesis, cell membrane construction, and metabolic pathways.
dotiwala and others have focused on a metabolic pathway that is critical to most bacteria but is missing in humans, making it an ideal target for antibiotic development.
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Imaging Research on the New Coronavirus (COVID-19). Springer Journal。
Time of Update: 2020-12-30
In order to quickly share the latest scientific research results and evidence to understand the new coronavirus infection and its imaging characteristics, Chinese Journal of Academic Radiology intends to solicit academic articles related to COVID-19 imaging research for all imaging experts in China and abroad.
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New mechanisms for metabolism to regulate thrombosis and new targets for treatment have been revealed
Time of Update: 2020-12-30
, by analyzing clinical samples of patients with type 2 diabetes, the researchers found that BCAA levels in patients' plateplates and key gene expression levels that regulate BCAA's decomposition metabolism were significantly associated with high plateboard reactiveness in patients.
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Gut microbes affect muscle atrophy
Time of Update: 2020-12-30
researchers found that in mice with common ALS gene mutations, changing the gut microbiome with antibiotics or feces transplants could prevent or improve disease symptoms.
researchers initially studied alS gene mutations in a Harvard lab by modeling mice.
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Scientists have revealed new mechanisms between ADHD and sleep disorders
Time of Update: 2020-12-30
Recently, Feng Jianfeng and Luo Qiang, dean of Fudan University's Institute of Brain Intelligence Science and Technology, in collaboration with the University of Cambridge in the United Kingdom and the University of Ottawa in Canada, made important progress in the study of ADHD and sleep disorder co-disease, found brain imaging evidence of early ADHD symptoms causing late-stage sleep problems, and prompted the relevant molecular biology process.
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Chinese scholars have identified a medium antibody that prevents the new coronavirus from invading
Time of Update: 2020-12-30
The researchers found two human-specific antibodies that prevent the new coronavirus S protein-binding domain RBD from binding to the human cell-like ACE2.
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A new strategy for metabolic intervention to treat liver failure is proposed
Time of Update: 2020-12-30
In vitro studies have found that inhibiting fatty acid oxidation and passive enhancement of glycolysis can improve the survival rate of liver cells in high ammonia and low oxygen micro-environments.
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The results of the research on the treatment of new crown pneumonia were published in the University of Science and Technology of China
Time of Update: 2020-12-30
There was a 1 week of routine treatment history before the use of toad monotherapy, but the symptoms did not improve, on average, after 5.6 days all patients had different degrees of deterioration of the condition, persistent fever, hypoxemia, lung CT showed progression of lesions.
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The study found anti-aging compounds
Time of Update: 2020-12-30
Aiming at the important characteristics of senescing cells, the research team cleverly designed and synthesized a new compound, which proved that the compound can effectively remove the accumulated senescing cells of multiple tissue organs in aging individuals, significantly improve the physiological state of elderly mice, and restore the body function of elderly mice.