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Sun Beicheng and Lin Anning's research team cooperate to reveal a new mechanism of liver cancer transformation regulation
Time of Update: 2021-05-31
The latest research results of the research team of Sun Beicheng and Lin Anning proved that abnormal liver cell NF-κB activity, whether it is missing or increased, can induce inflammatory tumor microenvironment through different molecular mechanisms, thereby promoting the occurrence and development of liver cancer.
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Merck's K-drug combination therapy for esophageal cancer receives positive opinions from the European Union
Time of Update: 2021-05-31
(Sina Pharmaceutical News) Reference source: Merck Receives Positive EU CHMP Opinion for KEYTRUDA® (pembrolizumab) in Combination With Chemotherapy as First-Line Treatment for Certain Patients With Esophageal Cancer or HER2-Negative Gastroesophageal Junction (GEJ) Adenocarcinoma According to foreign media reports, Merck announced on May 24 that the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion and recommended the approval of Merck’s anti-PD-1 therapeutic drug KEYTRUDA combined with platinum and fluorouracil.
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Depression takes two steps
Time of Update: 2021-05-31
At the same time, the depression recognition model based on gait features constructed by machine learning technology is effective (sensitivity=0.
" Zhu Tingshao said: "Automatic depression recognition based on machine learning technology is effective.
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GSK/Vir neutralizing antibody sotrovimab was granted emergency use authorization by the U.S. FDA
Time of Update: 2021-05-31
(Sina Pharmaceutical News) Reference source: FDA authorizes Vir-GSK antibody as variants threaten Eli Lilly mAb On May 26, the US FDA granted emergency use authorization (EUA) for the COVID-19 monoclonal antibody drug sotrovimab for mild to moderate patients who tested positive for the virus and have a high risk of developing severe COVID-19 (including hospitalization and death) Adults and adolescents (12 years and older, weighing at least 40 kg) patients.
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Raise cholesterol?
Time of Update: 2021-05-31
Vimal Karani, Professor of Nutritional Genetics and Nutritional Genomics at the University of Reading, said: “We have found that people who carry genetic variants related to high milk intake have higher BMI and body fat, but importantly, their Good cholesterol and bad cholesterol levels are lower.
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Optogenetic therapy restores partial vision for blind people
Time of Update: 2021-05-31
In the study, they injected an adeno-associated virus vector (used to assist in gene therapy) encoding the optogenetic receptor ChrimsonR into one eye of a 58-year-old blind male patient with retinitis pigmentosa, while using engineered goggles to perform Light stimulation.
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GSK adjuvant recombinant new crown vaccine enters Phase 3 clinical trials
Time of Update: 2021-05-31
com/en-us/media/press-releases/gsk-and-vir-biotechnology-announce-sotrovimab-vir-7831-receives-emergency-use-authorization-from-the -us-fda/ On May 27, local time, GlaxoSmithKline (GSK) announced that it has launched a phase 3 clinical trial of the adjuvant recombinant COVID-19 candidate vaccine developed in cooperation with Sanofi (SNF), which is expected to be in the United States, Asia, and Africa.
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"The Lancet" report: China's maternal and child health core indicators continue to improve
Time of Update: 2021-05-31
In addition, in response to the needs of women and children for high-quality health care services and a number of emerging issues and challenges, the report formulated a strategic framework for maternal and child health for the "Healthy China 2030", and pointed out that China is committed to the realization of the United Nations in the next 10 years.
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Scientists reveal a new mechanism for ROS to regulate the occurrence of uveal melanoma
Time of Update: 2021-05-20
Therefore, the researchers used different concentrations of carbon dot nanomaterials to induce UM cells to produce different levels of ROS, comprehensively analyzed whether it can have different effects on the occurrence and development of tumor cells, and explained the mechanism behind this phenomenon from the perspective of tumor metabolism.
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Trials show that AI guidance can help early detection of heart disease in routine practice
Time of Update: 2021-05-20
The ECG AI-guided Low Ejection Fraction Screening (EAGLE) test aims to determine whether artificial intelligence (AI) screening tools developed using ECG data can improve the diagnosis of this condition in routine practice.
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Scientists reveal a new mechanism of colorectal cancer microenvironment T cell metabolism regulation
Time of Update: 2021-05-20
Through gene knockout mice and colorectal tumor models, the MondoA-TXNIP transcriptional regulatory axis was discovered The research results were published online in "Gastroenterology" on the metabolic mode of Treg cells in the tumor microenvironment and the key regulatory mechanism of plasticity.
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Aspirin may help reduce the impact of air pollution on cognitive function
Time of Update: 2021-05-20
Aspirin may help reduce the impact of air pollution on cognitive function Aspirin may help reduce the impact of air pollution on cognitive function Aspirin may help reduce the impac
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Does weight loss rebound?
Time of Update: 2021-05-20
Research leader Signe Torekov, a professor in the Department of Biomedical Sciences, said that by testing four different treatments after diet-induced weight loss, researchers have for the first time clarified how obese people can maintain weight loss for a long time.
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Scientists in my country have discovered genes that cause cleavage disorders in fertilized eggs
Time of Update: 2021-05-20
Li Lin of Capital Medical University, and discovered the CHEK1 mutation of the first cleavage disorder of the fertilized egg and the mechanism of female infertility, and found a potential treatment method It provides new ideas for the treatment of infertility for such special patients.
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Qian Junbin et al. Reveal the mechanism of breast cancer immunotherapy and propose new methods for predicting efficacy
Time of Update: 2021-05-20
The study used single-cell multi-omics sequencing technology to analyze the changes in the tumor microenvironment before and after breast cancer immunotherapy, revealing the mechanism of anti-PD-1 therapy and proposing a new method for predicting efficacy.
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Thin people are also prone to heart disease?
Time of Update: 2021-05-07
Abdominal obesity is also related to the accumulation of fat around the liver, which usually leads to non-alcoholic fatty liver, which increases the risk of cardiovascular disease.
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Cancer cells can spread through the interstitium
Time of Update: 2021-05-07
A study by Neil Theise, a liver pathologist at New York University’s Rothman School of Medicine recently published in "Communications-Biology" showed that there is a continuous network filled with fluid between human cells , which spans organs or is related to the spread of disease.
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Anti-aging drugs improve glucose metabolism
Time of Update: 2021-05-07
A small clinical trial for postmenopausal women with prediabetes showed that compound nicotinamide mononucleotide (NMN) improves the ability of skeletal muscle to take up glucose, which is usually abnormal in patients with obesity, prediabetes or type 2 diabetes of.
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There is an answer to the problem of early gastric cancer screening!
Time of Update: 2021-05-07
” Not long ago, Guo Jintao, deputy director of the Endoscopy Diagnosis and Treatment Center and Digestive Endoscopy Treatment Ward of Shengjing Hospital, China Medical University, said in an interview with China Science Daily that early screening is the key to scientific prevention and control of gastric cancer.
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Genetic mutations make pregnant women heart "broken"
Time of Update: 2021-05-07
The researchers also found that in the sampled patients, the proportion of short variants in the other three genes previously unrelated to PPCM but related to DCM was also too high.
