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Study finds that husband drinking before pregnancy may increase the risk of birth defects in offspring
Time of Update: 2021-05-07
The study found that the husband drinking before pregnancy may increase the risk of birth defects in the offspring.
, for the first time suggested from epidemiological evidence that drinking alcohol before pregnancy may increase the risk of birth defects in offspring , May be related to sperm development and epigenetic modification regulation, and changing drinking behavior may reduce this risk.
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Scientists find differences in neural circuits for drug pain and euphoric memory extraction
Time of Update: 2021-04-22
When drug addicts encounter an environment where they have used drugs to produce euphoria, or there has been no drugs The environment that produces withdrawal pain can extract the euphoric memory and the painful memory from the relevant clues in these environments, which can cause the drug-seeking/medicine impulse and lead to drug relapse.
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"Mr. Critical" for Imatinib resistance has been found
Time of Update: 2021-04-22
Therefore, from the perspective of functional genomics, Wang Yuexiang’s research team proved for the first time that CDK1 is the offensive weakness of imatinib-resistant gastrointestinal stromal tumors, and clarified the new functions and substrates of CDK1 outside the cell cycle, and proposed CDK1 drive The treatment strategy of gastrointestinal stromal tumors provides new strategies and preclinical experimental data for overcoming imatinib resistance.
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Gene therapy is expected to treat rare eye diseases
Time of Update: 2021-04-22
Research results show that this therapy, whether used alone or in combination with other gene therapies that promote eye health, may provide a new way to preserve vision for patients with eye diseases such as retinitis pigmentosa.
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Hungry fast?
Time of Update: 2021-04-22
The scientific research team of King's College London and the health science company ZOE has figured out why some people still struggle to lose weight even if they control calorie intake, and emphasized the importance of understanding individual metabolism in terms of diet and health.
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Cellular immunology research suggests new ideas for the treatment of autism
Time of Update: 2021-04-22
The research team further confirmed by studying the above-mentioned new experimental animal models that the offspring of sick mice have abnormal peripheral and central immune lineages until they reach adulthood, and found that their T cell profile characteristics are consistent with those of some autistic patients; and that sick mice have social interaction defects, The core symptom of autism with repetitive stereotyped movements and communication disorders.
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Sun Yat-sen University discovers new targets for colorectal cancer treatment
Time of Update: 2021-04-17
On the contrary, pyrazofurin, an inhibitor of DKC1, significantly inhibits the expression of ribosomal proteins such as RPS3 and has anti-tumor activity.
Chen Shuai pointed out that the above research shows that DKC1 is a new candidate target for the treatment of colorectal cancer.
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What makes the protein channel open and close
Time of Update: 2021-04-17
Image source: Rockefeller UniversityMSCS channel protein (pink) and its related lipids (dark green, light green, red) are embedded in the nanodisc (gray).
Image source: Rockefeller University MSCS channel protein (pink) and its related lipids (dark green, light green, red) are embedded in nanodiscs (gray).
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Xenotransplantation, the root cause of the ineffectiveness of some cancer drugs
Time of Update: 2021-04-17
com Researchers at the University of Texas at Houston have discovered many potential reasons why anticancer drugs that kill tumor cells in mouse models do not work in human trials-xenotransplantation (PDX).
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Significant progress in the study of drug-resistant plasmids
Time of Update: 2021-04-17
Significant progress in the study of drug-resistant plasmids Significant progress has been made in the study of drug-resistant plasmids The reporter learned from South China Agricultural University that the postdoctoral fellow Yang Jun, under the guidance of Professor Liu Jianhua of the School of Veterinary Medicine and Professor Wang Haihong of the School of Life Sciences, has made important progress in the research of drug-resistant plasmids, and published the relevant research results in Nucleic Acid Research as the first author.
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Establish an artificial biosynthetic pathway for the anti-tumor drug candidate icariin
Time of Update: 2021-04-17
The Zhou Zhihua research group of the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences and the team of researcher Wang Ying from the South China Botanical Garden of the Chinese Academy of Sciences established for the first time an artificial biosynthesis pathway for the late-stage liver cancer drug candidate icariin.
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Polysaccharide diet is not good for children's brain development
Time of Update: 2021-04-17
Recently, a new study led by researchers at the University of Georgia and the University of Southern California showed through rodent models that daily consumption of sugar-sweetened beverages during adolescence can impair learning and memory in adulthood.
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New results help type 1 female "sugar friends" nurture healthy babies
Time of Update: 2021-04-17
Beginning in 2015, Weng Jianping’s team has designed and united with a number of units to carry out the "Carnation" research project to improve the pregnancy outcome of Chinese type 1 diabetic women through the implementation of a whole-process management program for pregnancy and childbirth.
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Scientists discover that the glutamate transmitter system controls the electrical activity of the heart
Time of Update: 2021-04-16
Scientists discover that the glutamate transmitter system controls the electrical activity of the heart Brings new ideas to the prevention and treatment of arrhythmia Scientists foun
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Go one step further!
Time of Update: 2021-04-16
Scientists propose a new treatment plan for esophageal cancer Recently, the research team of Professor Adam Bass of Harvard Medical School’s Dana-Farber Cancer Institute published a paper in the academic journal Enterology (GUT), revealing the combination of CDK4/6 inhibitors and pan ERBB family inhibitors can effectively inhibit the growth of esophageal squamous cell carcinoma.
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Biometabolism molecule creatine can promote cancer metastasis
Time of Update: 2021-04-16
Researchers found that creatine can increase the expression of cancer metastasis molecules SLUG/SNAIL by activating the downstream effector molecule SMAD2/3 of TGF-β, and promote the infiltration and metastasis of tumor cells.
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Breastfeeding can prevent obesity in adults
Time of Update: 2021-04-16
Recently, researchers have discovered through studies on breast milk that an alkaloid called betaine in whole grain foods can promote the growth of beneficial bacteria in the intestinal tract of newborns, thereby increasing long-term metabolism and reducing the incidence of obesity.
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Advances in research on the origin and evolution of breast cancer cells
Time of Update: 2021-04-13
This study promotes the understanding of the mechanism of BRCA1 mutant breast cancer, and suggests that the abnormality of normal breast tissue in BRCA1 mutation carriers before tumorigenesis may become an early warning marker and potential intervention target.
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Northwest snack "slurry" can relieve gout
Time of Update: 2021-04-13
This study isolated Lactobacillus fermentum JL-3 from traditional fermented food slurry and found that it can control the accumulation of uric acid in tissues by degrading uric acid in animals, and revealed the specific mechanism of action.
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97% of vaccinated persons can produce neutralizing antibodies after 3 doses
Time of Update: 2021-04-13
In addition, in February this year, the Gaofu team released part of the results of the international phase 3 clinical trial in bioRxiv, showing the neutralizing effect of the domestic recombinant protein subunit new crown vaccine ZF2001 on the new South African variant (501Y.
