-
Yingfeng Tu/Yingjia Li, Southern Medical University, Fei Peng, Sun Yat-sen University: Joint microenvironment-driven nanorobots for precise active treatment of rheumatoid arthritis
Time of Update: 2023-01-01
AdvancedScienceIntroduction to the journalAdvanced Science is a high-quality open source journal founded in 2014 by Wiley, publishing innovative achievements and cutting-edge progress in various fields such as materials science, physical chemistry, biomedicine, and engineering.
-
Immunity View: Regulatory T cells as metabolic sensors
Time of Update: 2023-01-01
Written by | A fish in the nineteenth century, physiologist Claude Bernard wrote that "only the stability of the internal environment can have free and independent existence", and later, the character
-
Can vitamins, salt and cayenne peppers affect rheumatism? That's the right way to eat!
Time of Update: 2023-01-01
Figure 1: Complex association between diet and rheumatism The role of different substances in dietary interventions for rheumatismMost of the body's immune cells are located in the digestive tract, and nutrients (vitamins, salts, fatty acids, etc.
-
Xerostomia vs xerostomia, what is the difference in medication?
Time of Update: 2023-01-01
👇Download the Decision Assistant App, the guide is free at any time~▼▼▼Click to read the original article to download the AppFor medical professionals onlyFor more guidelines for the diagnosis and treatment of common rheumatology diseases, go to the "Clinical Decision Assistant App"!
-
When a rheumatologist encounters discoloration of the fingers and toes, how to grasp the essence of differential diagnosis?
Time of Update: 2023-01-01
Common causes of acral ischemia refer to the differential diagnosis of (toe) ischemia In general, when clinical suspicion of discoloration of the fingers (toes) due to limb ischemia is encountered, acute phase reaction markers such as erythrocyte sedimentation rate (ESR) should be screened first, and the test results should be preliminarily judged whether it is vascular disease or vasculitis.
-
How can I tell if I really have gout? The guide proposes these four criteria
Time of Update: 2023-01-01
How to do the long-term management of gout?What are the goals for controlling blood uric acid levels?What clinical signs and symptoms are prioritized for diagnosing a disease?Open the Decision Assistant App Clinical Guidelines moduleSearch for the name of the disease you want to know and talk to authoritative guides at home and abroad!
-
On the new, Takara integrates UMI's human BCR profiling kit!
Time of Update: 2023-01-01
The immune repertoire (IR) refers to the sum of all functionally diverse B cells and T cells in an individual's circulatory system at any given time. B cells are an important component of the adaptiv
-
Key breakthrough, Yale University once again focuses on small animal in vivo imaging technology, the latest Immunity of new crown research has come out!
Time of Update: 2023-01-01
Recently, in a new study published in Immunity, a research team led by Yale University in the United States used bioluminescence imaging technology to capture the transmission of SARS-CoV-2 (new coron
-
Immunity human immunoglobulin profiling guides vaccine immunogen design targeting broad neutralizing antibody precursors of HIV V2-apex
Time of Update: 2023-01-01
Schief's team from the Scripps Research Institute in the United States published an article in the journal Immunity Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors In their paper, they utilized structural modeling, VDJ recombinant analysis of known V2-apex bnAbs, and bioinformatics analysis of ultra-deep next-generation sequencing (NGS) of human BCR heavy chains (HCs) from 14 HIV-unexposed donors to assess the frequency of relative potential precursors.
-
Suspected of ankylosis? In fact, it is this difficult to diagnose spondyloarthritis
Time of Update: 2023-01-01
At present, there are no verified diagnostic criteria for nr-axSpA, and spondyloarthropathy, including many rheumatic immune diseases, is classified according to patients with similar symptoms, classified into axial SpA or nr-axSpA, but this classification standard is not suitable for diagnosis.
-
Is it difficult to achieve standard treatment for AS? The new standard may be useful!
Time of Update: 2023-01-01
The 2016 International Association for the Evaluation of Spondyloarthritis (ASAS) and the European Union Against Rheumatism (EULAR) updated management guidelines support the use of T2T regimens in axSpA。 T2T is a completely new treatment concept and management model, from disease activity status criteria to response criteria, axSpA compliance treatment goals have changed several times.
-
What is the difference between commonly used vitamin D and analogues in clinical practice?
Time of Update: 2023-01-01
Nutritional vitamin D intake recommendations (for reference only): The chemical structure calcifediol is the main form of vitamin D in the blood, with a long half-life (12~20 days), which is an objective indicator reflecting whether vitamin D is deficient.
-
How is the periconceptional period managed in patients with vasculitis? The first comprehensive guide publishes the guideline consensus
Time of Update: 2023-01-01
Medication management during pregnancyA variety of treatments for vasculitis can be used during pregnancy, including azathioprine, colchicine, TNF inhibitors, cyclosporine, tacrolimus, and nonsteroidal anti-inflammatory drugs.
Medication management during pregnancyA variety of treatments for vasculitis can be used during pregnancy, including azathioprine, colchicine, TNF inhibitors, cyclosporine, tacrolimus, and nonsteroidal anti-inflammatory drugs.
-
First update in 16 years! What is the new classification standard for antiphospholipid syndrome?
Time of Update: 2023-01-01
*For medical professionals only, reference 1999→2006→202X? Antiphospholipid syndrome (APS) as one of the important causes of acquired thrombophilia and recurrent miscarriage, more and more clinicians
-
Deliver innovative CD38 inhibitors! Boehringer Ingelheim refers to immune and fibrotic diseases
Time of Update: 2023-01-01
In addition, we believe that this agreement, along with RBN-2397 and RBN-3143, which we are evaluating in clinical trials, further validates our potential therapeutic options and capabilities to discover and develop NAD+ utilization enzymes using the BEACON+ platform.
-
The 3 hot topics in the diagnosis and treatment of Sjogren syndrome can be read in one article
Time of Update: 2023-01-01
Common sense cognition of lymphatic aggregation in pathological sections of pSS salivary glands: 2 main modes of SS involvementIn the systemic manifestations of SS, lung and kidney are the two main organs affected, and about 10%-20% of patients with SS are affected by the lungs, while renal involvement is mainly renal tubular acidosis.
-
Lupus occurs in these situations, the guide teaches you to deal with it properly!
Time of Update: 2023-01-01
How are glucocorticoids used to treat patients with SLE?How should patients be treated when they have organ and system involvement?Where can I find more guidelines for the diagnosis and treatment of common rheumatology diseases?Open the Decision Assistant App Clinical Guidelines moduleSearch for the name of the disease you want to know and talk to authoritative guides at home and abroad!
-
The ultra-sensitive fluorescence detection kit Stellar shocked the market
Time of Update: 2023-01-01
Fully automated, multifunctional, ultra-sensitive fluorescence Western revolutionizes Western Blot technology ProteinSimple officially released the Stellar Ultra-sensitive Fluorescence Detection Kit
-
From the perspective of domestic and foreign guidelines, the strategies of chronic rheumatic diseases in women of childbearing age were discussed
Time of Update: 2023-01-01
Of all current TNF-α inhibitors, the American College of Rheumatology (ACR) is the only one that strongly recommends peselizumab for the entire course of disease management (pregnancy, pregnancy, and lactation) in women of childbearing age.
-
Progress has been made in the study of the natural immune regulation mechanism of plants
Time of Update: 2023-01-01
The phosphorylation state of CPK28 determines its ubiquitination modification and protein stabilitySource: Agricultural Resources Research Center, Institute of Genetics and Development, Chinese Academy of SciencesThis account manuscript opens WeChat "Quick Reprint" by defaultPlease indicate the source of reproductionFor other channels to reprint, please contact weibo@cashq.
