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Blood: miR-125a-5p regulates the formation of platelet precursors by actin binding protein L-Plastin.
Time of Update: 2020-07-27
There is a genetic variation in platelet counting between individuals !----, which better understands its regulatory genetic factors or the process of resolving platelet generation MicroRNAs (miRs) a
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Blood: Risk stratified adaptive therapy for acute lymphoblastic leukemia.
Time of Update: 2020-07-27
Infants with acute lymphoblastic leukemia (ALL) !----, especially those carrying the KMT2A gene rearrangement (KMT2A-r), have a poor prognosis Japan has been working hard to study the role of stem ce
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Circulation: Reducing the intake of branched chain amino acids reduces the risk of thrombosis associated with metabolic syndrome.
Time of Update: 2020-07-27
!---- branched chain amino acids (BCAAs) are essential nutrients, including leucine, isoleinine, and proline, which can be used as raw materials for energy production as well as regulators for importa
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Blood: Tumor-related myelin cells provide important support for T-ALL.
Time of Update: 2020-07-27
Al !----though there are mutations in cancer-causing and anti-cancer genes that promote cancer growth, acute T-lemphoblastic leukemia (T-ALL) cells still require exoplanets or signals to survive in vi
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Blood: NCOA4 mediates hepatic iron reserve mobilization after blood loss.
Time of Update: 2020-07-27
!----: The mobilization of the hepatic iron reserve after NCOA4 mediated blood loss, and the Expression of NCOA4 is increased by HIF-1 alpha/HIF-2 alpha-dependence in conditions that promote HIF stabi
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Nat BME : A biomaterial-based vaccine that causes a persistent tumor-specific response to acute myeloid leukemia.
Time of Update: 2020-07-27
acute myeloid leukemia (AML) is a malignant tumor that originates in hematopoietic disease and has limited treatment !---- cell-reducing chemotherapy standard therapy is to deplete AML cells to induc
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Circulation: Deep vein thrombosis in patients hospitalized with Xinguan pneumonia in Wuhan.
Time of Update: 2020-07-27
The purpose !---- of this study is to investigate the incidence of deep vein thrombosis (DVT) in patients with new coronary pneumonia in patients who were hospitalized, including their incidence, risk
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NEJM: Indo-Indo-Indo-Indo-Indo-Case Report.
Time of Update: 2020-07-27
The patient !----, a 72-year-old man who had been suffering from fatigue and right hip pain for one month, was referred to the haematology department and found to have abnormal serum protein electroph
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Axa Pharmaceuticals has been awarded the second orphan drug title by the FDA: Bcl-2 inhibitor APG-2575 for the treatment of Fahrenheit polycypproteinemia.
Time of Update: 2020-07-27
as !---- centage Pharma has announced that its new Bcl-2 inhibitor, APG-2575, is treating Fahrenheit polycylobinemia (WM), and has been awarded the orphan drug (ODD) by the U.S Food and Drug Administr
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Blood: Hematopoietic cell transplantation for chronic granuloma disease: 712 cases study
Time of Update: 2020-07-16
!---- chronic granulated disease (CGD) is a primary immunodeficiency disease that can lead to life-threatening infections and inflammatory complications allo-HCT can cure patients, but the transplant
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Lancet Haematol: Dynamic monitoring of blood and clotting parameters provides more accurate and convenient assessment of the condition and prognosis of PATIENTs with COVID-19
Time of Update: 2020-07-16
!---- 2019 coronavirus disease (COVID-19) has become endemic worldwide, posing a serious threat to human health Changes in hematological characteristics in patients with COVID-19 are becoming an impo
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Blood: Adding rapamycin to the GVHD prevention program can significantly improve the prognosis of HCT patients with HLA antigen mismatch
Time of Update: 2020-07-16
the purpose !---- of this study is to evaluate the efficacy of adding rapamycin to postoperative hematopoietic cell transplantation (HCT) anti-host disease (GVHD) in the treatment of cyclosporine and
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Blood: Progenion of large B-cell lymphoma (PMBCL) treated with R-CHOP
Time of Update: 2020-07-16
the combination of the !----, litoxiin, increases the cure rate for primary isolation of large B-cell lymphoma (PMBCL) but the type of major therapy and the role of radiotherapy (RT) are still unclea
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Blood: Single-cell sequencing reveals transcription factors and molecular pathways that drive HSC in vitro production
Time of Update: 2020-07-16
!---- hematopoietic stem cells and progenitor cells (HSPc) develop through different waves at different anatomical sites during embryonic development in vitro differentiation of human pluripotent ste
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Blood: Think very scared, HIV-positive people also go to donate blood!
Time of Update: 2020-07-16
!---- Background: Antiretroviral therapy (ART), used to treat and pre-exposure prophylaxis (PrEP, which is to take precautions before infection, such as using condoms during sex) is an effective way t
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Blood: Exogenous antigens successfully significantly enhance immune depletion of HIV CAR T cell amplification
Time of Update: 2020-07-16
!---- CAR T cells targeting CD19 plus hematologic malignancies, springing up, quickly becoming a promising new treatment , on the contrary, the results of several CAR T-cell studies of infectious dise
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Blood: Regulation mechanism downstream of platelet collagen receptor GPVI
Time of Update: 2020-07-16
!---- platelets are involved in the healing of vascular damage through coordinated adhesion, secretion, and aggregation reactions rapid and progressive changes in platelet morphology patterns and fun
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1 case of red blood cell hyperactivity positive for CALR gene mutation
Time of Update: 2020-07-16
!----'s CALR gene mutation is commonly found in patients with primary platelet growth (ET) and primary bone marrow fibrosis (PMF) in my-eloproliferative tumors (my-eloproliferative neoplasms, MPN), and is rarely reported in patients with true erythropoietin (PV)?
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First iPSC-derived CAR-T cell therapy: IND approved by FDA
Time of Update: 2020-07-16
!---- Fate Therapeutics, a clinical-phased biopharmaceutical company dedicated to the development of cellular immunotherapy against cancer and immune diseases, announced today that the FDA has approve
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Blood: CAR-modified memory-like NK cells significantly improve NK's therapeutic response to resistant lymphoma
Time of Update: 2020-07-16
!---- NK cell is a promising immunotherapy for tumor cells cytokine-induced memory sample (ML) NK cells differentiate after being activated by IL-12, IL-15 and IL-18, exhibiting a strong anti-tumor r
