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NAT MED: "Human pig complex" can help restore damaged human lungs
Time of Update: 2020-07-16
!---- Patients waiting for a lung transplant face a higher waiting list mortality rate because the injury makes most donor lungs unusable Although in vitro pulmonary perfusion (EVLP) restores margina
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Review: Selected by Blood Research on July 9, 2020
Time of Update: 2020-07-16
!---- Three aspirin treatments in the optimization of icharacteristic platelet hyperplasia patients with antiplatelet treatment comparison https://doi.org/10.1182/blood.2019004596 ispecial-hairplatele
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Bood: Prediction and prevention of CNS recurrence in patients with extracellular natural killing/T-cell lymphoma
Time of Update: 2020-07-13
The incidence of recurrence of the central nervous system (CNS) was different from previously reported due to the improvement of the survival prognosis of patients with the of endoco oma/T cells l
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Blood: BET inhibitor CPI203 promotes umbilical cord blood HSC and macrophage amplification
Time of Update: 2020-07-13
Although cytokine-mediated artificial blood stem cell (HSCs) amplification can lead to high production of hematopoietic progenitor cells, this is usually at the expense of reducing the regenerativ
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Bcl-2 combined BTK inhibitors for the treatment of chronic lymphocyte lymphoma
Time of Update: 2020-07-13
Ascentage Pharma, which is developing new treatments for cancer, chronic hepatitis B and aging disorders, today announced a clinical trial with AstraZeneca to study aPG-2575 (a selective Bcl-2 inhib
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Blood: IL-18 and cytotoxic damage are the independent and synergistic drivers of viral induced super-inflammation
Time of Update: 2020-07-13
Blood-phytomotic lymphocytic hyperactivity (HLH) and macrophage activation syndrome (MAS) are life-threatening hyper-inflammatory syndromes, usually associated with underlying blood disease and rheu
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Blood: Genomics and Epigenetic Analysis of The Subtypes of Cell Lymphoma
Time of Update: 2020-07-13
Set cells lymphoma (MCL) are mature B-cell tumors, initially driven by CCND1 rearrangement, with two molecular subtypes, conventional (cMCL) and non-lymph node leukemia (nnMCL), which have differe
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Blood: Immune synaptic components HLA-II and CD58 Activate Rose Knot T Cells
Time of Update: 2020-07-13
Note: T-cell rose knot, is the name of sheep red cell (SRBC) combined with a rose knot on the surface of T cells T cells bind to SRBC because the cell surface has a class of receptors that bind to S
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Blood: Quantitative proteomics reveals the unique metabolic characteristics of AML stem cells
Time of Update: 2020-07-13
Acute myeloid leukemia (AML) is characterized by the accumulation of cloned myelin cells that cannot differentiate into mature white blood cells Chemotherapy can relieve most patients, but the recur
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FDA approves first oral drug for patients with recurrent or refractive large B-cell lymphoma: nuclear export inhibitor XPOVIO
Time of Update: 2020-07-13
Karyopharm Therapeutics announced that the U.S Food and Drug Administration Administration ( FDA ) has approved the company's first-class oral nuclear export selective inhibitor XPOVIO (selinexor
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Blood: 14-3-3-c-Src-integrator-beta-3 complex is essential for platelet activation!
Time of Update: 2020-07-13
Several adapter molecules bind to the intracellular end of beta-integrator to promote bidirectional signalconducting, which is essential in thrombosis formation and hemorrhage Interfering with int
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Blood: FXII and peptide progenitors and gC1qR/C1QBP/P32 asymmetrical assembly are subject to variable structure regulation
Time of Update: 2020-07-13
The contact system, also known as the plasma kinetics release enzyme-kinpeptide system, consists of factor XII (FXII), kinetic release enzyme (PK) and cofactor kinegen (HK) Spherical C1q receptors (
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Blood: The mother ferritin, not the fetal iron tone, determines the fetal iron steady state!
Time of Update: 2020-07-13
Iron disorders are associated with poor pregnancy outcomes, but we still know little about the mechanisms that maintain iron stability during pregnancy In humans and rodents, the iron-regulating hor
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Blood: Mechanism of immunoglobulin light chain in light chain deposition disease
Time of Update: 2020-07-13
Light chain deposition disease (LCDD) is a rare disease characterized by monoclonal immuno globulin (Ig) light chain (LC) in renal glomerular and renal tube amorphous deposition, leading to nodule
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"Stocking up" On July 2, 2020 Blood Research Select
Time of Update: 2020-07-13
1 : in acute lymphoblastic leukemia, E2A-PBX1 is a secondary activation factor RUNX1 E2A is a basic helical-ring-helix (bHLH) transcription factor that plays a vital role in determining the f
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Blood: Neusonocell mesh trap promotes immune thrombosis in patients with acute crying in COVID-19
Time of Update: 2020-07-13
Center point: in COVID-19 ARDS, the neutrophil mesh trap (NETs) causes micro thrombosis formation through platelet-neutral granulocyte interaction The new NET suppressor factor (nNIF) blocks TH
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IDELVION has been approved in Europe, becoming the first and only clotting factor IX therapy to be administered every 21 days
Time of Update: 2020-07-13
CSL Behring has announced that the European Drug Administration Bureau (EMA) has approved its new long-acting recombinant albumin fusion IX coagulation factor IDELVION (albutrepenonacog alfa) for
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Blood: Treating Refractable/Recurrent Non-Hodgkin's Lymphoma with CD19/CD20 CAR T Cells
Time of Update: 2020-07-13
The chimeric antigen receptor T (CAR T) cells targeted at CD19 have made breakthroughs in the treatment of malignancies in the hematologic system (e.g., recurrent/refractive non-Hodgkin lymphoma ,
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Clin Cancer Research: Tazemetostat (EPZ-6438) Joint R-CHOP treatment of diffuse large B cell lymphoma
Time of Update: 2020-07-13
BACKGROUND: Histone methyl metastase EZH2 is the catalytic sub-base of the PRC2 complex involved in transcription regulation, with about 25% of patients with birth center B cells lymphoma carrying
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Blood: The mechanism by which malaria parasites develop in human red blood cells and affect host red blood cell generation
Time of Update: 2020-07-13
BACKGROUND: The malaria parasite has two hosts, mosquitoes and humans, in the human body has been parasitic in liver cells and red blood cells, cracking proliferation (schizogony) In red blood cells
