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BJH: New advances in the treatment of recurrent/refractive invasive B cells in children and non-Hodgkin's lymphoma.
Time of Update: 2020-08-01
The prognosis of R/R B-NHL patients was poor, with a survival rate of between 10 and 36 percent in recent reports, and only those who were able to perform an autologous or allogeneic hematopoietic stem cell transplant (HSCT) had a higher survival chance.
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Anti-CD20 mono-anti-kop: from a generation of litoxitostos to three generations of attozhu.
Time of Update: 2020-08-01
the first generation of anti-CD20 monotonic, in addition to the heavy product ritus, including rat-source monoantiapizumab (commodity name: Zewarin), The world's first radioactively labeled monoantiapiate, first developed by IDEC, in the United States in 2002, was approved for treatment of relapsed B-cell non-Hodgkin lymphoma.
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MiR-155 inhibitors treat T-cell lymphoma and are designated by the FDA for orphan drugs.
Time of Update: 2020-07-30
Cobomarsen, a miR-155 inhibitor developed by miRagen, is currently being developed in two clinical studies to treat different types of T-cell lymphoma, including Phase 2 clinical trials for skin T-cell lymphoma (CTCL) and Phase 1 clinical trials for adult T-cell leukemia/lymphoma (ATLL).
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In danger of the blood routine reversal, 99% of people do not understand!
Time of Update: 2020-07-30
in addition, Zhang Shimin teacher of a case, is because of the attention of two blood routine results of MCV and MCHC changes, through analysis finally found that the specimen was forgotten to a few days after the result of delivery.
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Nat Commun: The Mei Yang/Yu Peng team reveals the key process of mDia2 regulating bone marrow transplantation of hematopoietic stem cells.
Time of Update: 2020-07-30
!---- hematopoietic stem cells (HSPCs) are the "source" of blood cells in the body, mainly in the stem cell "niche" in the bone marrow. HSPCs have the ability to migrate, return home, and re-implante
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Brit J Heamatol: Hydroxyurea exposure in women with sickle cell disease with ovarian reserve.
Time of Update: 2020-07-30
!---- For women with sickle cell disease (SCD), the use of modern ovarian reserve measures may help resolve the question of whether SCD or hydroxyurea (HC) affects female reproductive life.
the median level of AMH was consistent with reduced ovarian reserve (a risk factor for infertility), which occurred in subjects aged 25-30.
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Blood: Iron chelation for the treatment of hemolytic anemia and skin photosensitivity for congenital erythropoietin.
Time of Update: 2020-07-30
treating uroS defects with oxytotone and peripheral blood CD34 plus red blood cells from patients with CEP inhibited the expression of the ferrite-dependent proteins ALAS2 and IRP2 and reduced the production of radon.
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Medicine: Tosili beads monotonica repellent treatment of ineffective and intolerable familial Mediterranean fever open label trial.
Time of Update: 2020-07-30
in general, the study is expected to provide evidence on the long-term safety of TCZ as a potential new therapeutic drug for PATIENTs with autumn daffodil resistance or autumn daffodil intolerance.
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Blood: Enhanced subgene recombination mediates the occurrence of platelet disease in Quebec.
Time of Update: 2020-07-30
!----: In QPD, PLAU repetition disrupts genomic structure, alters the interaction of the enhanced subgene and gene, and leads to overexpression of cell type specificity.
results show that QPD repetition causes an ectopic interaction between PLAU and a conservative macronuclear cell enhancers found in the same topological association domain (TAD).
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JAMA Intern Med: The largest serological survey in the United States shows that the actual number of people infected should be 6-24 times higher.
Time of Update: 2020-07-29
!---- Currently, according to real-time data from Johns Hopkins University in the United States, the total number of confirmed cases of new crown pneumonia in the United States is 3.94 million But a n
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Blood: Prognosis for patients with Burkitt lymphoma over the past decade.
Time of Update: 2020-07-29
!----: In adult BL, 19% of patients have central nervous system conditions, 14% of all patients are primary and refractive diseases, TRM is 10%, and PFS is 64% in 3 years The researchers identified fo
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Cell Rep: Domestic scholars have made new advances in the study of fever-related platelet-reducing virus-induced inflammatory responses.
Time of Update: 2020-07-29
!---- recently, the National Key Laboratory of Virology, Peng Yu, and Xiao Yufu's research team published their latest research in the international academic journal Cell Reports online, the paper ent
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Sci Adv: The Jian Zhu team reveals that drug apron SPLK1 effectively assists in the removal of HIV-1 latent cell cells.
Time of Update: 2020-07-29
!---- combined antiretroviral therapy (combined antiretroviral therapy, cART) can effectively suppress the viral load of HIV-1 in the peripheral blood of patients and thus greatly delay the life of AI
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Natno Biotechl: Hematopoietic stem cell gene editing strategy update! More efficient and more applicable.
Time of Update: 2020-07-29
!---- Hematopoietic Stem Cell (HSCs) Targeted Gene Editing is a promising and promising treatment for a wide range of diseases It can achieve in situ correction, functional restoration and physiologic
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FDA approves CAR-T cell therapy Tecartus for relapsing refractive lymphoma.
Time of Update: 2020-07-29
Auto, a unit of !---- gides Al-Gilead Sciences, recently announced that the FDA has approved CAR-T cell therapy Tecartus (also known as KTE-X19) for the treatment of recurrent refractive lymtocyte lym
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J Hematol Oncol: University participants have discovered important regulatory roles in acute myeloid leukemia with new small molecule RNA.
Time of Update: 2020-07-29
Recently, !---- professor Zeng Hui, director of the Department of Hematology, a clinical first-level leader at the First Hospital affiliated with Jinan University, has made important progress in the f
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A selection of Blood Research On July 23, 2020.
Time of Update: 2020-07-29
1.!---- CDK6, NUP98 fusion protein and acute myeloid leukemia https://doi.org/10.1182/blood.2019003267 fusion proteins associated with nucleoporous protein 98 (NUP98) recur in acute myeloid leukemia (
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The world's first CRISPR gene editing treatment for beta 0/beta 0 was successful at the Nanjing 2020 BPIT Conference.
Time of Update: 2020-07-28
July 22, 2020 / emedclub news / - - on July 21, 2020, bpit 2020 was held in emaker At the conference of biological innovative drug technology, Dr. Wu Yuxuan from Shanghai bangyao Biotechnology Co., Lt
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The world's first CRISPR gene-editing treatment for beta 0/beta 0 was successful.
Time of Update: 2020-07-28
On July 22, 2020, Shanghai bangyao Biotechnology Co., Ltd., which focuses on gene therapy and cell drug research and development, announced that the clinical trial of "clinical study on the safety and
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J Thromb Haemost: The combined effects of five thrombosis genotypes and cancer on the risk of first venous thromboembolism events.
Time of Update: 2020-07-27
!---- The role of the combined thrombosis genotype in cancer-related venous thromboembolism (VTE) has rarely been studied , researchers used a population-based case queue to explore the effects of a f
