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Science Liver Battlefield – The Difference Between Immunity and Metabolism in Men and Women
Time of Update: 2022-10-25
"An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice Scientists at the University of California, San Francisco (UCSF) have developed a new approach based on evolutionary biology to study sexist diseases.
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Cancer Science: Drug properties that make cancer metastasis treatments more effective
Time of Update: 2022-10-25
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
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Nature: The first induced pluripotent stem cell model for post-traumatic stress disorder
Time of Update: 2022-10-25
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression The skin cells were reprogrammed into induced pluripotent stem cells and then turned into neurons exposed to stress hormones, which were then observed by the team.
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Guangzhou Health Center has made new progress in the synthesis of chiral pyridinolinspircene
Time of Update: 2022-10-25
Palladium-catalyzed diiminocyclization with high enantioselectivity to construct pyridinolene Some compounds and their optical properties are studied Links to papers Recently, the research group of Zhu Qiang of the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, etc.
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Experiments on the International Space Station reveal the risks of future human spaceflight
Time of Update: 2022-10-25
Image credit: Takashi Morita, OMUAn international team of researchers conducted a long-term experiment on the International Space Station to test the effects of space radiation on mouse embryonic stem cells.
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Progress has been made in the study of hydrological connectivity and its water environment effects in arid inland river basins
Time of Update: 2022-10-25
05), and the water resources of river basins in arid areas were formed in mountainous areas, while precipitation in plain areas was scarce, except for extreme heavy rainfall, which had almost no hydrological significance and was difficult to replenish rivers, resulting in a significant negative correlation between hydrological connectivity and actual evapotranspiration (ETa) (pTRS_Editor P{margin-top:0px;margin-bottom:15px;line-height:2;font-family:;font-size:12pt;}.
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The research team of the Institute of Microbiology revealed a new mechanism of intestinal flora protecting cardiovascular health
Time of Update: 2022-10-25
The team of Liu Hongwei/Liu Shuangjiang of the Institute of Microbiology found that a fungal active molecule could significantly improve the symptoms of atherosclerosis in mice, and further intestinal microbiota analysis found that after oral administration of this molecule, the abundance of Parabacteroid merdaede fecal core bacteria increased by 420 times.
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Cell Discovery Gao Zhaobing's research group collaborated to reveal the molecular mechanism by which MLKL channels perform cell death and neuroinflammation
Time of Update: 2022-10-25
Recently, the research team of Gao Zhaobing, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, together with Dr. Wang Sheng of Fudan University, proved that PIP2 is an endogenous agonist of MLKL channels, and PIP2 enhances channel function and "ignites" MLKL-mediated procedural necrosis and inflammatory immune responses 。 The research results were published in the international journal Cell Discovery under the title "Enhanced channel activity by PI(4,5)P2 ignites MLKL-related pathogenic processes".
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Nature: Scientists studying the DNA of more than 5 million people revealed genetic traits associated with human height
Time of Update: 2022-10-25
Recently, in a study published in the international journal Nature entitled "A saturated map of common genetic variants associated with human height", scientists from the University of Queensland and other institutions conducted the largest genome association study ever, using DNA from more than 5 million people in 281 studies.
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The key laboratory has made progress in the research of fucoidan sulfate tumor immunotherapy
Time of Update: 2022-10-25
A few days ago, the academic journal International Journal of Biological Macromolecules published a report by the Seaweed Chemistry and Marine Drugs Research Group of the Key Laboratory of Experiment
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New research is an important step towards curing AIDS
Time of Update: 2022-10-25
Currently, antiretroviral therapy (ART) is mainly used to treat HIV and prevent the onset of AIDS, which suppresses the amount of virus in the blood and partially restores the immune system.
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PNAS: A new cancer treatment that targets the immune system's "brakes."
Time of Update: 2022-10-25
Ultimately, blocking FOX3P with SAHs may be an effective way to inhibit treg while cancer patients receive other immunotherapies designed to boost the immune response to tumor cells.
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The epigenetic changes associated with Parkinson's disease differ in men and women
Time of Update: 2022-10-25
Articles Parkinson's disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons According to a new study from Rutgers University, the epigenetic changes associated with Parkinson's disease are different in men and women.
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Chemicals in the environment increase the risk of inflammatory bowel disease
Time of Update: 2022-10-25
"It is well known that environmental factors are as important as genetic factors in influencing autoimmune and inflammatory diseases, but we lack a method or platform to systematically determine the effects of chemical candidates on inflammation," said corresponding author Francisco Quintana, PhD, a researcher at the Brigham Ann Romney Center for Neurological Disorders, whose lab previously studied the environmental determinants of neurodegeneration.
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Destroy bacteria with tomatoes!
Time of Update: 2022-10-25
”essayFinding a Needle in a Haystack: Producing Antimicrobial Cutin-Derived Oligomers from Tomato Pomace Figure: Developing an antimicrobial blend from discarded tomato peels In recent years, agro-industrial residues have been used to develop bioplastics, food supplements and other applications.
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PNAS: A new chemical proteomics approach enables global analysis of arginine dimethylation
Time of Update: 2022-10-25
Article Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect–based chemical-enrichment method Protein arginine methylation plays an important role in regulating protein function in different cellular processes, and its regulation is abnormal, which can lead to a variety of diseases.
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Quantitative study of atmospheric nitrogen uptake and NH3 interception in soil emission in rice canopy in Nanjing soil...
Time of Update: 2022-10-25
The plant canopy is a key place for the exchange of substances and energy between crops and the outside world such as water, air and heat, and due to the two-way exchange between the canopy and the a
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PLoS ONE: Central Asia is considered an important region for human ancestors
Time of Update: 2022-10-25
"A study of "Paleolithic occupation of arid Central Asia during the Middle Pleistocene" was published in PLoS General:https://journals.
"A study of "Paleolithic occupation of arid Central Asia during the Middle Pleistocene" was published in PLoS General:https://journals.
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Monkeypox virus was detected in the testicles of nonhuman primate survivors
Time of Update: 2022-10-25
Retrospective detection of monkeypox virus in the testes of nonhuman primate survivors Immunofluorescence staining shows that monkeypox virus (green) can be detected in the epididymal cavity (red) of crab-eating macaques infected with acute monkeypox infection, which is where sperm maturation and storage.
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Science cover story: Gene-edited butterfly mutants reveal secrets of ancient "junk" DNA
Time of Update: 2022-10-25
”References: A new study explains how DNA located between genes — known as "junk" DNA or noncoding regulatory DNA — fits into a basic program that has been preserved for tens to hundreds of millions of years, while allowing wing patterns to evolve extremely quickly.
