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A common infection can cause cancer
Time of Update: 2022-09-30
Reference: Human Colon Cancer –Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice A new study suggests that a Closedtridioides difficile infection causes certain colorectal cancers.
Reference: Human Colon Cancer –Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice A new study suggests that a Closedtridioides difficile infection causes certain colorectal cancers.
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Cell Reports simulates a fasted diet that reduces dementia symptoms in mice
Time of Update: 2022-09-30
Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer’s models According to a new study led by the University of Southern California, Leonard Davis College of Geriatrics, simulating fasting diet cycles appears to reduce signs of Alzheimer's disease in genetically engineered mice.
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New PNAS research shows that epigenetic memories are passed on across multiple generations
Time of Update: 2022-09-30
In the resulting offspring, the researchers observed abnormal patterns of gene expression, in the absence of inhibitory epigenetic markers, where genes on the father's chromosome (inherited from sperm) were turned on or "up-regulated.
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The new model states that Alzheimer's disease is not a brain disease, but an autoimmune disease
Time of Update: 2022-09-30
Scientists at the Klimbil Brain Institute have come up with a new model of the mechanism of Alzheimer's disease (AD2) that sees it as a chronic autoimmune disease that attacks the brain, rather than a brain disease.
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PNAS: There is a new understanding of the nucleotide excision repair process
Time of Update: 2022-09-30
”essayTwo interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair Image: Irradiate cells with ultraviolet light and observe the co-localization of XPA with the site of UV damage with a fluorescence microscope.
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PacBio has announced a new method for comprehensive genome-wide tandem repeat analysis
Time of Update: 2022-09-30
TRGT and TRVZ are now available on GitHub PacBio (NASDAQ: PACB), a leading developer of high-quality, high-precision sequencing solutions, today announced a new computational analysis method that analyzes more than 1 million tandem repeats (TRs) in the human genome using PacBio's native long-read HiFi sequencing data.
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Cell Rep: How oncogenes regulate genetic variation in prostate cancer
Time of Update: 2022-09-30
In this study, the team found that the oncogene FOXA1 is a key regulator of selective splicing in prostate cancer and may control the generation of splicing variants that can affect disease recurrence and patient survival.
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Nature Sub-Journal: A Controlling Factor for the Control of Fungal Infections in Wheat
Time of Update: 2022-09-30
A new molecular tool can detect non-pathogenic spores (red) and invasive hyphae (green) by microscope Photo credit: Professor Gero Steinberg and Professor Sarah GurrThe fungus Zymoseptoria tritici causes wheat black spot disease, the most damaging fungal disease of wheat grown in temperate regions of the world.
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The Shen Yongxing Research Group of the University of Michigan at Jiaotong University realized the asynchronous solution of the dynamic fracture problem
Time of Update: 2022-09-30
Recently, the team of Shen Yongxing of the Michigan Institute of Shanghai Jiao Tong University published an online report entitled "An asynchronous variational integrator for the phase field approach to dynamic fracture" in the International Journal for Numerical Methods in Engineering, a top journal in the field of computational mechanics (a method of nonsynchronous variational integral for solving dynamic fractured phase fields) research paper.
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Give immunotherapy cells the elasticity to pass the "stress test"
Time of Update: 2022-09-30
"By knocking out a single gene, the cells we create are not only effective tumor cell killers, but also more persistent killers over a long period of time," said Julia Carnevale, m.
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Congratulations to Professor Zhou Shaohua on his election to MICCAI FELLOW
Time of Update: 2022-09-30
On September 21, 2022, Dr. Zhou Shaohua, Chair Professor of the University of Science and Technology of China, Founding Executive Dean of the School of Biomedical Engineering, Director of the Center for Medical Imaging Intelligence and Robotics Research (MIRACLE Center), Visiting Researcher of the Institute of Computing of the Chinese Academy of Sciences, and Visiting Professor of the Chinese University of Hong Kong (Shenzhen), was elected as MICCAI Fellow for his contributions to medical imaging computing theory and clinical translation.
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Publish a map of blood metabolites dominated by gut bacteria
Time of Update: 2022-09-30
An online atlas of human plasma metabolite signatures of gut microbiome composition Tove Fall is a professor of molecular epidemiology at the Department of Molecular Epidemiology Medicine, Uppsala University, Sweden.
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PNAS: A novel protein that mediates chloroplast protein transport
Time of Update: 2022-09-30
"The results of this study can be used to improve the photosynthetic capacity of non-chloroplast algae (algae other than chlorophylls, from which land plants are produced), which are in the seaOriginal title:A distinct class of GTP-binding proteins mediates chloroplast protein import in Rhodophyta Oceans are often referred to as the last border of the earth.
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Progress has been made in the study of species-specific antiviral immune regulatory mechanisms in aquatic habitats
Time of Update: 2022-09-30
FTRCA1 is significantly expressed at viral infection and plays a negative role in regulating interferon antiviral responses by degrading the protein kinase TBK1 in the RLR signaling pathway (J Immunol 2019; 202:2407-2420）。 Recently, the team's findings proved that FTRCA1 is not only an E3 ubiquitin ligase, but also an RNA-binding protein.
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PNAS: A novel protein that mediates chloroplast protein transport
Time of Update: 2022-09-30
"The results of this study can be used to improve the photosynthetic capacity of non-chloroplast algae (algae other than chlorophylls, from which land plants are produced), which are in the seaOriginal title:A distinct class of GTP-binding proteins mediates chloroplast protein import in Rhodophyta Oceans are often referred to as the last border of the earth.
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The team of Xie Jingyuan and Yu Zhangsheng of Shanghai Jiaotong University found that air pollution particulate matter PM2.5 may increase the risk of kidney failure in IgA nephropathy
Time of Update: 2022-09-30
The team of Professor Xie Jingyuan, Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, and the team of Professor Yu Zhangsheng, School of Life Science and Tec
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Immune cells that are more easily suppressed allow to receive transplanted organs
Time of Update: 2022-09-30
"essayReduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival Patients who receive organ transplants must take potent drugs to prevent the immune system from rejecting the organs.
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Nature Sub-Journal: How Inflammation Caused by Injury or Illness Recovers
Time of Update: 2022-09-30
The researchers defined common health trajectories based on how quickly white blood cells and platelets returned to normal after the inflammatory responseThis finding could help clinicians recognize and intervene more quickly when the recovery process is not going wellThe team's ultimate goal is to establish a personalized recovery trajectory that enables patients to recover from a wide variety of medical and surgical conditions and can be used in clinical settings.
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Massachusetts General Hospital has developed a new type of hydrogel that promotes healing of burn wounds
Time of Update: 2022-09-30
Bioengineers at Massachusetts General Hospital have recently developed an advanced hydrogel that promotes wound healing from second-degree burns and dissolves quickly and easily during dressing changes, minimizing pain and trauma in patients.
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The "bacterial enzyme" discovered more than a decade ago is extremely important for the regulation of many diseases in humans
Time of Update: 2022-09-30
If we can control the autoregulator and set it up the way we want it in different tissues, we may one day be able to slow or even stop the progression of some diseases," said Dr. Amanda Casey, an assistant professor of molecular biology and a former postdoc in UTSW Orth's lab.
