-
Regulatory mechanism of gut microbiome in the formation of anti-vibriomycosis traits in semi-slippery tongue rays
Time of Update: 2022-09-30
Based on the multigenerational selection of the semi-slippery tongue fish disease resistance family by Academician Chen Songlin's team, this study analyzed the structural and functional differences, host gene expression patterns and flora-host interaction of the intestinal flora of the disease-resistant and susceptible families through multi-omics analysis, and found that the microbial community structure of the disease-resistant and susceptible families was significantly different: the disease-resistant families enhanced the anti-Vibrio infection ability by recruiting beneficial bacteria (such as Phaeobacter, Propionibacterium).
-
Single-cell multi-omics analysis provides an in-depth analysis of the tumor microenvironment of pancreatic cancer
Time of Update: 2022-09-30
They paid particular attention to cells that express acinar markers, as one theory suggests that pancreatic ductal adenocarcinoma originates from acinar cells that undergo acinar-duct metaplasia (ADM).
-
To explore the function of Huntington's chorea protein in damaged neurons
Time of Update: 2022-09-30
The study shows that HTT is involved in neuronal damage and regeneration — a new finding, said Dr. Gunawardena, an associate professor of biological sciences in Baja's College of Arts and Sciences.
-
Using the new technology, researchers have made surprising discoveries about how the brain responds to taste
Time of Update: 2022-09-30
In a new study published in Contemporary Biology, researchers at Brown University describe how they developed a new imaging technique and used it to map the neural activity of fruit flies in response to sweet and bitter tastes.
-
The OX40 protein has the potential to alleviate the main complications of leukemia treatment
Time of Update: 2022-09-30
Researchers at Baylor College of Medicine and its partner institutions have engineered immune cells to control two major life-threatening complications, graft-versus-host disease (GvHD) and cancer recurrence, which usually occur after allogeneic hematopoietic stem cell transplantation for leukemia (allo-HSCT).
-
Chinese scholars have made progress in the search for static neutron stars
Time of Update: 2022-09-30
Optical observation of the time domain of J1123. Above: the apparent velocity value of an M-type dwarf and the best-fitting apparent velocity curve; Below: The light curve of TESS, CRTS, ZTF, NEOWISE
-
Protein genomics reveals markers of chemotherapy resistance and prognosis in triple-negative breast cancer
Time of Update: 2022-09-30
”The research team used an innovative analytical method, and they previously developed a method called microscale protein genomics to analyze tumor biopsies of TNBC patients before receiving carboplatin and docetaxel combined chemotherapy.
-
The immune system reacts fatally to the lungs
Time of Update: 2022-09-30
Caryl Boies, Professor Caryl Boies, and his team at Cold Spring Harbor Laboratory (CSHL), have identified a drug candidate that can prevent deadly lung inflammation in mice by inhibiting a protein called PTP1B.
-
Scientists have finally discovered the origin of chromatin as well as the mysterious ancestors of eukaryotes
Time of Update: 2022-09-30
References: A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution In almost every human cell, a nucleus that is only one millionth of a meter wide must contain two meters of DNA.
-
Li Mingsong, a researcher at the School of Earth and Space, has made progress in the study of the Paleocene-Eocene extreme heat event
Time of Update: 2022-09-30
Earth system simulations and data comparisons suggest that astronomical drivers played a role in triggering the Paleocene-Eocene extreme heat eventThe paper was recently published in the internationally renowned journal Nature Communications, and the first and corresponding author is Li Mingsong.
-
What makes the roots of a plant grow in the direction of gravity? New PNAS research has uncovered four genes
Time of Update: 2022-09-30
"Because we have previously performed the same experiments on distant relatives of Arabidopsis plants, we were able to match genes within genome-related regions of both species.
"Because we have previously performed the same experiments on distant relatives of Arabidopsis plants, we were able to match genes within genome-related regions of both species.
-
Cell: A neural map of the sense of smell
Time of Update: 2022-09-30
"essayER stress?transforms random olfactory receptor choice into axon targeting precision Image: Labeled red and green in this illustration are sensory cell axons of a single glomere within the olfactory bulb of the mouse brain.
-
New machine learning methods better describe the progression of neurodegenerative diseases
Time of Update: 2022-09-30
Current clinical studies typically assume a downward linear downward trajectory in health status on symptom scales and use these linear models to assess whether drugs are slowing disease progression.
-
PNAS's knowledge of lysosomes has increased
Time of Update: 2022-09-30
”Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage Researchers at the Duke National University School of Medicine and colleagues in Singapore have discovered a protein that transports degraded membrane lipids out of lysosomes, which are the breakdown plants of cells.
-
PNAS The Link Between Tumor Stem Cells and Circadian Clock Proteins
Time of Update: 2022-09-30
The research team, led by the University of Southern California Keck School of Medicine, demonstrated that after current standard treatments, circadian clock proteins that help coordinate changes in body function throughout the day may play a key role in the growth and proliferation of glioblastoma.
-
What are the differences between the Bigleaf Mountain Pine and the Mountain Tree, in addition to the differences in morphology?
Time of Update: 2022-09-30
Kaempferia galanga galangaKaempferia galanga latifolia Lu Jianmei, a doctoral student of the Plant Genome Evolution and Secondary Metabolism Research Group of Banna Botanical Garden, under the guidance of researcher Xu Youkai, used flow cytometry to detect the ploidy of the mountain tree from Assam, India, the mountain tree from Haikou, Hainan Province, and the bigleaf mountain tree from Maguan, Yunnan, and Jinping in Yunnan, and found that the big leaf mountain was tetraploid and the mountain tree was five ploids.
-
PNAS: What if some stress really protects your body?
Time of Update: 2022-09-30
”essayChronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling Pictured: Psychological stress has been found to worsen the symptoms of inflammatory bowel disease.
-
Cell unravels a 50-year-long mystery, revealing how bacteria move
Time of Update: 2022-09-30
Egelman of the University of Virginia School of Medicine and his collaborators used cryo-electron microscopy to reveal how bacteria moved — ending a mystery that lasted more than 50 years.
-
AI empowers blood testing equipment, "wise eye" to interpret antibody strength - Suzhou Medical Institute proposed a new method of incomplete antibody grading detection
Time of Update: 2022-09-30
Figure 1: Incomplete antibody sample test reaction results (a) (-) grade; (b) (+) level; (c) (++) level; (d) (+++) level; (e) (++++) level The Gao Xin team of Suzhou Medical Institute of the Chinese Academy of Sciences assisted the team of the Blood Immunology Research Center to propose a new method for grading the intensity of incomplete antibody reaction strength (CBAM-CNN Ensemble Model) for the self-developed incomplete antibody intelligent interpretation device.
-
Protein genomics reveals markers of chemotherapy resistance and prognosis in triple-negative breast cancer
Time of Update: 2022-09-30
”The research team used an innovative analytical method, and they previously developed a method called microscale protein genomics to analyze tumor biopsies of TNBC patients before receiving carboplatin and docetaxel combined chemotherapy.
