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Nat Commun: Key genes regulate neurological disorders.
Time of Update: 2020-10-07
the study points to a genetic mutation called NEMF, a new driver of motor neurone disease.
Martin et al, NEMF mutations that ribosome-associated quality control are associated with neuromuscular disease, Nature Communications (2020).
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Cell Rep: Study reveals role of immune cells in brain infections.
Time of Update: 2020-10-07
findings, published in the journal Cell Reports, could help develop targeted treatments for brain infections, the most common cause of viral encephalitis worldwide.
researchers also identified the exact signaling protein, called CXCL1, which drives these destructive neutral granulocytes to the brain during HSV infection.
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Progress has been made in the study of nerve mechanisms that induce bone loss due to stress.
Time of Update: 2020-10-07
Type vesicle membrane glutamate transporter) and peripheral intersecting nerve activity to regulate chronic stress-induced bone loss symptoms: when animals are in an anxious state, BNST nucleus SOM neurons are activated, thereby inhibiting SF-1 neuron activity in VMH; these inhibited SF-1 neurons reduce the excitability of Vglut2 neurons in downstream NTS, causing increased peripheral sensory neuron activity.
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4, 2020 in the journal Science.
Time of Update: 2020-10-07
results were published online July 15, 2020 in the journal Science under the title "Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutics." co-author of the paper and head of the Department of Systemic Pharmacology and Translational Therapy at the Perelman School of Medicine at the University of Pennsylvania.
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JAMA Netw Open: No matter how much alcohol is consumed overall, drinking shrap results in a significant increase in an individual's risk of developing dementia.
Time of Update: 2020-10-07
doi:10.1001/jamanetworkopen.2020.16084 The results of this study show that alcohol-induced loss of consciousness is directly related to an increased risk of dementia in individuals, regardless of overall alcohol consumption.
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Exp Neurol: New study could help treat stroke.
Time of Update: 2020-10-07
when P2X4R is overactive, it causes a series of harmful effects in brain cells, leading to isoemia brain damage.
by blocking the activity of the subject, the researchers found that excessive immune responses were effectively suppressed to improve the recovery of acute and chronic strokes.
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Nat Methods: Dopamine receptors reveal chemical signals in the brain.
Time of Update: 2020-10-07
sensors will help researchers detect and monitor different information processing activities in the brain," said Lin Tian, lead author of the study and associate professor of biochemistry and molecular medicine at www.pixabay.com.
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Ann Neurol: New study helps promote neuron regeneration.
Time of Update: 2020-10-07
August 20, 2020 /--- Researchers at the University of Alberta recently found a treatment that can increase the rate of nerve regeneration by three to five times, promising better treatment for trauma surgery patients.
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J Neurosci: How does the brain perceive time?
Time of Update: 2020-10-07
after this adaptation period, they are shown the test stimulus and indicate its duration.
(bioon.com) Source: How the brain creates the experience of time Original source: Duration-Selectivity in Right Parietal Cortex Reflects the Core Experience of Time, JNeurosci (2020).
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Scientists hope to unlock the mysteries of the brain!
Time of Update: 2020-10-06
September 23, 2020 // -- In a recent study published in the international journal Nature Communications entitled "A spike-timing-dependent plasticity rule for dendritic spines", scientists from the University of Montreal and other institutions have uncovered the molecular mechanisms behind the body's memory and learning abilities, especially how the brain processes, stores and integrates information.
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Advances have been made in the study of neural mechanisms that encode similar male characteristics.
Time of Update: 2020-10-06
The study used calcium signal recording, chemical genetic manipulation and electrophysiology of brain tablets to analyze the prekernels of the lower papules by integrating olfactory information, specifically encoding the male information of the same species, and then regulating the cellular and neural loop mechanisms of mouse attack behavior.
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Neuron: Uncover the molecular mechanisms by which small glial cells shape neural circuits in the brain.
Time of Update: 2020-10-06
Photo Source: In Lucas Headle's study, researchers delved into the link between biology and the outside world, and researcher Lucas Cheadle says we are very interested in studying how neural circuits respond to sensory experiences; It's done, but it does require strong feedback from the environment to promote brain maturation, and when animals interact with their surroundings, some neuron connections are eliminated and others strengthened, a process that can last up to a decade after birth.
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Movement Disord: The new crown outbreak affects the treatment of Parkinson's disease.
Time of Update: 2020-10-06
September 23, 2020 /--- A global survey of health professionals led by Queen Mary University of London shows that during the COVID-19 pandemic, People with Parkinson's disease in Asia, Africa and much of Latin America and South America experienced difficulties in obtaining drugs that could lead to worsening symptom control.
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Nat Struct and Mol Biol: Early on on-oncercation type 2 diabetes is associated with a variety of neurodegenerative diseases The culprit is a special amyloid fiber!
Time of Update: 2020-10-06
Fibril structures of diabetes-related amylins reveal a basis for surface-templated assembly.
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Scientists use "smell training" bees to increase the seed yield of sunflowers.
Time of Update: 2020-10-06
"Walter Farina of the University of Buenos Aires, Argentina, said, "The most surprising and relevant result is that the foraging preference for the target crop is so persistent and dense that it contributes to a significant increase in crop yields." " Farina team has previously shown that bees can build stable, long-term memories of food smells in hives.
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Progress has been made in the study of flexible artificial synapses for intelligent bionic sensing systems.
Time of Update: 2020-10-06
In the simulation of the neural signaling process, the researchers used the selection and optimization of device materials, combined with biopathy perception mechanisms, to doped lithium perchlorate polyethylene polyoxide (PEO: LiClO4) and semiconductor-type single-wall carbon nanotubes (s-SWCNTs) as channel materials, the preparation of double-layer structure of memactile artificial synapses, to achieve the simulation of biological pain transmission and perception functions.
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Nature: Reprogramming brain cells may help the body make more flexible decisions.
Time of Update: 2020-10-06
Cells in this region initially follow the original pattern of activity, but then adapt to the new environment, and when specific neurons in the preaintmental corties of the eye socket are deliberately inactive, the mouse body's ability to re-learn is impaired, and the activity of the neurons in the sensory region no longer exhibits active modification or alteration.
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Cell: For the first time, a three-dimensional structure of hallucinogens combined with 5-HT2A serotonin ligands has been analyzed.
Time of Update: 2020-10-06
to fully study this potential, scientists need to know how these drugs interact with brain cells at the molecular level to cause their dramatic biological effects.
study was published in the September 17, 2020 issue of cell, under the title "Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor." from Cell, 2020, doi:10.1016/j.cell.2020.08.024.
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Nat Biotechnol: The relationship between sensory neuron activation and the immune system.
Time of Update: 2020-10-06
September 23, 2020 /--- In a recent study, scientists at Harvard Medical School/Boston Children's Hospital developed an implantable technique that can detect the interaction between sensory neurons and immune cells.
researchers have developed a soft implant that wraps the seism nerve and emits blue light on demand.
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New drug for epilepsy! Weisai Fycompa (Wexter ®, Villenem Panai) by the European Union CHMP recommended approval: expand the applicable population, treatment of children!
Time of Update: 2020-10-06
As an AMPA-like antagonist, Fycompa reduces excessive excitation of neurons associated with seizures by targeting the activity of the AMPA-Glutamate after synapses; To date, Fycompa has been approved by more than 70 countries worldwide, including Japan, the United States, China, and other countries in Europe and Asia, as an ancillary therapy for the treatment of partial seizures (POS, with or without secondary systemic seizures) in patients aged 12 and over.
