-
Nat Commun: The VEGF-like vaccine showed initial efficacy in neurofibromatosis type 2.
Time of Update: 2020-10-13
, we presented exploratory clinical studies of the VEGFRs peptide vaccine in 7 patients with progressive NF2-based schizophrenic tumors, the results of which were published online in Nat Commun.
after two patients were vaccinated, VEGFRs were observed to show a significant decrease in expression in the split tumor.
-
Alzheimer's and Dementia: Cognitive depression screening factors in normal older adults.
Time of Update: 2020-10-13
")。 In order to determine whether depressive symptoms on GDS (15 versions), including self-reported memory problems, varied depending on brain amyloid protein β (A beta) levels (a pathological marker of early AD), the researchers investigated potential measurement deviations in A-beta levels, as well as measurement deviations attributable to cognitive function levels and gender as positive controls.
-
JNNP: Clinical observational study of exoimmune esophysiology in patients with Louis' dementia and Alzheimer's disease.
Time of Update: 2020-10-13
, however, the second most common neurodegenerative disease in dementia, DLB, is not known.
T and B cell sub-groups of individual nuclear cells in outer blood were measured by a flow cytometer, and the concentration of serum cytokines was determined by multiple immunoanalysis.
-
Little mung beans in the head, not only make people fat but also infertility?
Time of Update: 2020-10-13
Fat, there are many reasons why some people may be born and obese some people may be fat some people fat, may be because the disease in the field of neurosurgery has a disease called pituitary tumor w
-
Cell: Solved nearly a hundred years of problems! The study found the underlying pathways of "swinging through" memory.
Time of Update: 2020-10-13
these findings confirm that orphaned subjects are effective modifiers for short-term memory, and complement the classical PFC-based model with a framework centered on the emerging pasalpyric brain, thus providing a mechanism understanding of working memory.
-
Commun Biol: Energy differences between sobriety and sleeping neurons in the lower cortical layer.
Time of Update: 2020-10-13
At the same time, although the brain's hemodynamics increase at the same time, the level of neuron ATP during fast eye movement sleep is significantly lower, indicating a negative balance of energy in neurons, possibly due to the fact that rapid eye movement sleep specifically promotes energy-consuming activities such as heat generation.
-
Cytokine: CXCL12 promotes the proliferation of radioactive glial cells after brain trauma in rats.
Time of Update: 2020-10-13
7 days after TBI, brain tissue was immune-fluorescent double-label staining of BdU/Nestin, BLBP/Nestin, BLBP/Vimentin, BLBP/SOX2, BLBP/CXCR4, BLBP/DCX.
results showed that CXCL12 treatment significantly increased the number of cells stained around the injured cortical and cytosome areas of BdU/Nestin, BLBP/Nestin, and BLBP/Vimentin compared to the control group.
-
JAMA Neurol: In-hospital stroke patients infusion treatment rate and functional prognostic study.
Time of Update: 2020-10-13
2.7%), while the proportion of inpatient stroke patients using venous thrombosis (19.1% vs 9.1%) and intravascular therapy (6.4% vs 2.5%) increased significantly, with a significant increase in 2015.
-
Peking University Research: People with bad eyes and backs are more likely to suffer from dementia and depression.
Time of Update: 2020-10-13
Compared to subjects without visual, auditory or double sensory impairment, subjects with sensory impairment scored lower on situational memory, mental well-being, and overall cognitive ability, and had a higher prevalence of depression.
-
Acta Neuropathologica: 1q chromosome mosaics in human brain tissue are associated with one-sided multiple brain retardation, early onset epilepsy, and severe stunting.
Time of Update: 2020-10-13
analysis of copies of DNA methylation data showed that 7 out of 26 PMG patients had a uniform repetition throughout the long arm of chromosome 1, as confirmed by additional fluorescent in-place hybridization analysis.
-
Nat Neurosci: Study reveals mechanisms of memory formation.
Time of Update: 2020-10-13
Oct 7, 2020 //--- When the brain forms a new experience of memory, neurons called engram cells encode the details of the memory and reactivate it each time we recall it later.
-
JAMA Network Open: Disrupting Cognition, a 10-year follow-up study has shown that moderate drinking protects brain function and improves cognitive ability.
Time of Update: 2020-10-13
study looked at the relationship between drinking in middle-aged and older adults and changes in cognitive function over time, and showed that small or moderate amounts of alcohol consumption protected brain function in older adults.
-
Nature: How does the brain distinguish between the present and the past?
Time of Update: 2020-10-13
current study, scientists are trying to identify cell molecules or substrates to store long-term threats and memories associated with security tips.
, however, is the first study to link the need for new protein synthesis in these neurons to the stability of long-term emotional memory.
-
Science: Study reveals regenerative mechanisms of neurons in the brain and eye.
Time of Update: 2020-10-13
researchers modified zebrafish's Müller glial cells to a similar state, preventing reprogramming and regenerating regenerating regenerating retinal neurons in mouse models.
-
Will Neuralink be the only medical guide when the brain-computer interface shines into reality?
Time of Update: 2020-10-10
's prediction of a "human machine" will come true, but in July this year, a news that Neuralink's "brain-computer interface" (BCI) technology had made a major breakthrough and that the device had been licensed by the FDA's "breakthrough device program" was like a bulletin proclaiming that the "human-machine" combination had become a reality.
-
Bluebird's breakthrough gene therapy Lenti-D is on the market! Improves long-term survival outcomes in patients with fatal rare disease CALD.
Time of Update: 2020-10-10
From the DATA from the FDA's granting of Lenti-D breakthrough therapy and the study data based on Bluebird's application to the EMA for listing, Lenti-D showed good therapeutic potential for early CLADA patients to delay disease progression, and no transplant anti-host disease, organ rejection or donor organ failure was reported.
-
NEJM: Galen Malformed Veins - Case Report.
Time of Update: 2020-10-10
veins are a rare congenital venous fistula in the brain that can lead to heart failure in newborns and pulmonary hypertension.
the child was treated with an intravascular embolism in a malformed vein.
-
Treatment or breakthrough of neuroblastoma: Nivatrotamab receives FDA "Orphan Drug Title" and "Rare Paediatric Disease Title"
Time of Update: 2020-10-10
biopharmaceutical company Y-mAbs Therapeutics announced today that the FDA has awarded its leading dual-specific antibody nivatrotamab the title of orphan drug (ODD) and the title of rare pediatric disease (RPDD) for the treatment of neuroblastoma.
-
JNNP: New study could improve the accuracy of Parkinson's predictions.
Time of Update: 2020-10-07
September 17, 2020 /--- A study led by Queen Mary University of London suggests that genetic markers can improve the predictive accuracy of Parkinson's disease.
-
J Neuroinflammation: Developed the first targeted antibody therapy that promises to be effective in treating Alzheimer's disease.
Time of Update: 2020-10-07
based on this study, the researchers found that using TREM2 to activate antibodies to therapeutically target the effect of TREM2 may activate small glial cells and recruit small glial cells into amyloid plaques to reduce amyloid plaques Accumulation, which ultimately improves the cognitive abilities of patients, and most importantly, is the first method to target TREM2 to promote the removal of amyloid plaques in the brain, which are thought to be the main cause of Alzheimer's disease.
