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Current Biology: Brain stimulation improves memory of time and space travel
Time of Update: 2021-02-10
a new study by Northwestern Medicine, supported by the U.S. National Institute of Mental Health, improves memory of complex, real-world events like these by applying transcranial magnetic stimulation (TMS) to brain networks responsible for memory.
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Stroke: Women vs. Differences in men's risk of stroke and transient ischemic episodes depend on age
Time of Update: 2021-02-04
this, the researchers hypothesically assumed that women's risk of stroke was generally lower than men's, but that risk differences varied between age groups, further assessing the effect of age on the relationship between gender and the incidence of stroke or TIA seizures.
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Nature: Asstary glial cell-induced inflammation of the central nervous system is associated with gut microbes!
Time of Update: 2021-02-04
Quintana team named "Gut-licensed IFN plus NK cells drive LAMP1 plus TRAIL plus anti-ingy astrocytes." mouse experiments have shown that LAMP1-TRAIL-asstary glial cells limit inflammation of the central nervous system (CNS) by inducing T-apoptosis, which is maintained by meninges IFN-NK cells and regulated by intestinal microorganisms.
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Lancet Neurology: The safety and effectiveness of the treatment of multiple sclerosis fatigue with amines, modaphines and methyls: a randomized, crossover, double-blind trial
Time of Update: 2021-02-04
Fatigue, defined as a subjective lack of physical or mental energy that an individual feels in their daily activities, is one of the most common and disabling symptoms of multiple sclerosis (MS) and affects more than 75% of patients at some point during the illness.
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Science Advances: Didn't get a good night's sleep, and it was the moon's fault? Human sleep with the moon cycle
Time of Update: 2021-02-04
researchers found that participants in all three communities showed the same sleep oscillation patterns as the moon went through its 29.5-day cycle: total sleep time varied by an average of 46 to 58 minutes over the lunar phase cycle, with bedtimes varying by about 30 minutes.
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Stoke: Women vs. Differences in men's risk of stroke and transient ischemic episodes depend on age
Time of Update: 2021-02-04
this, the researchers hypothesically assumed that women's risk of stroke was generally lower than men's, but that risk differences varied between age groups, further assessing the effect of age on the relationship between gender and the incidence of stroke or TIA seizures.
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Nat Commun: How does Pytha Russell inhibit A-beta 42 accumulation?
Time of Update: 2021-02-04
, it is important to understand the aggregation process of A beta 42 at the molecular level in order to develop effective treatment strategies designed to inhibit its self-assembly.
results establish infrared nanospectroscopy as a powerful tool for structural drug discovery for diseases caused by protein misfolding.
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Crit Care: Motion Recorder monitors the feasibility and reliability of sleep analysis in intensive care patients
Time of Update: 2021-02-04
the prospective observational study monitored the sleep of patients with minimal sedation using a 24-hour multi-guided sleep tracing and motion recorder to assess consistency, total sleep time, and wakefulness time for both methods.
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Alzheimer's and Dementia: ApoE4 affects Alzheimer's disease by regulating inflammation and neurotrophic factors
Time of Update: 2021-02-04
To better understand the role of APOE 4 in preclinical AD, researchers recently stratited the absence (APOE 4-) or presence (APOE4) of APOE by layering levels of pathogenic, neurotrophic, and inflammatory proteins in the plasma of patients with external EVs (pEVs) and cognitive impairment, dementia-free (CIND).
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Behavioural Brain Research: Studying abhorrent spontaneous brain activity from resting fMRI and EEG
Time of Update: 2021-02-04
excluding the effects of age and gender, the results of this study show that the DS-R score and the correction time of category C (R s 0.221, P we use two brain imaging techniques, resting fMRI and resting EEG, to reveal spontaneous brain activity patterns that are closely related to aversion sensitivity).
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Acta Neuropathologica: Children's on-screen tube melanoma: not just RELA or YAP
Time of Update: 2021-02-04
addition to the room tube mesothelioma with RELA fusion, YAP1-MAMLD1 fused tumors are thought to be the second entity to appear in the children's curtain chamber.
in this study, we reported 18 cases of non-RELA/non-YAP on-screen tracheal membrane tumors in children, which were systematically characterized through their histology, immunosomics, genetics, and epigenomics.
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Gan Li Pharmaceuticals' candidate drug GLR2007 has been "fast track qualified" by the FDA
Time of Update: 2021-02-04
GLR2007 is a cell cycle protein-dependent kinase 4/6 (CDK 4/6) inhibitor being developed by Ganli Pharmaceuticals for the treatment of advanced solid tumors, including glioblastoma.
one-year survival rate was 39.3% in patients with glioblastoma.
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Behavioural Brain Research: Drd2rs6277 Polymorphism, Environment, and Gender Interactions on Impulsiveness in Representative Population Studies
Time of Update: 2021-02-04
the purpose of this study is to explore the role of gender in these results by further investigating the relationship between DRD2 rs6277 and early adversity of behavior and self-reporting impulses, as well as alcohol use in a representative sample of populations.
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JAMA | 66 years of data show: TIA is small, stroke risk is not small!
Time of Update: 2021-02-03
results showed that TIA patients had a 4.5-5 times stroke rate compared to non-TIA participants after adjusting for other vascular risk factors, such as high blood pressure, high cholesterol, or diabetes.
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JPs Res: Blood tests can be used to diagnose depression and bipolar disorder
Time of Update: 2021-02-03
results showed a significant decrease in serum mBDNF levels in the severe depression (MDD) group (n-90) and bipolar disorder (BD) group (n-15), while there was no significant change in the suicide group (n-14) compared to the control group (n-96).
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Neurology: A joint study by top U.S. universities found risk factors for hereditary Alzheimer's disease
Time of Update: 2021-02-02
by observing changes in treatment trials in patients with DIAD, which could help better understand the meaning of CMHs, Nelly Joseph-Mathurin of the University of Washington and others used data from the explicit genetic Alzheimer's Network (DIAN) to Amyloid-relatedimaging abnormalities, ARIA-H) is evaluated and tracked over a long period of time to identify clinical risks associated with CMHs and to identify characteristics of high-risk individuals with hemorrhagic amyloid-associated imaging abnormalities (ARIA-H).
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The study reveals the neural associations of social semantic accumulation
Time of Update: 2021-02-02
research shows that in addition to the general factors of the field (such as the length of meaning units), the type of semantic information is also an important factor affecting the neural association of semantic accumulation, which provides a new enlightenment for the study of semantic accumulation.
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Neurology: Inflammation-related plasma proteins can reflect seizures
Time of Update: 2021-02-02
serum oxytocin levels have been proposed as biomarkers to distinguish between ES and PNES, however, a meta-analysis of 15 studies assessed serum oxytocin and other markers such as ACTH, cortisol, neurons Heteroolase, creatinase, glutamate transaminase and brain-source neurotrophic factors indicate that although these serum protein levels may change after ES, they are excluded from clinical practice due to lack of diagnostic sensitivity, specificity and accuracy.
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Neurology: The risk of suicide increased significantly in patients with isolated dystia disorder
Time of Update: 2021-02-02
In this way, given the stigma surrounding suicide and the tendency of people with suicidal tendencies to avoid clinical intervention, we speculate that suicide in patients with dystory disorder may not be disclosed in routine neurological assessments, further increasing the risk of suicide in these patients." we conducted an anonymous electronic study that looked at the demographics and suicide rates of 542 people with different forms of isolated dystia and their relationship to co-existing mental illness.
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Scientists have developed a new drug delivery platform that can pass through the blood-brain barrier
Time of Update: 2021-02-02
researchers used PLGA to develop a nanoscale surface protein that combines the therapeutic drug siRNA to maximize penetration of the blood-brain barrier in laboratory mice.
