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Lower odds of pregnancy and childbirth after single ovary IVF
Time of Update: 2022-04-26
"Our meta-study shows that women with only one ovary are less likely to have IVF success than women with both ovaries intact," says Karolinska Karolinska Institutet, Associate Professor, Department of Oncology Pathology, Karolinska Institutet said Kenny Rodriguez-Wallberg, a consultant at the University Hospital of Cardiff .
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New findings may help reduce side effects of multiple sclerosis drugs
Time of Update: 2022-04-26
"This discovery will help us improve drugs to treat multiple sclerosis and reduce their side effects," said study co-senior author Xin-Yun Huang, Ph. D.
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Obesity treatment only for women?
Time of Update: 2022-04-26
Based on their findings, the researchers believe that increasing the production of the KLF14 protein in women's fat cells may offer a way to treat the deleterious effects of obesity and type 2 diabetes .
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How chronic pain occurs
Time of Update: 2022-04-26
Researchers have now identified an epigenetic factor, histone deacetylase 4 (HDAC4), which is a key factor in gene expression in dorsal horn neurons .
In experiments with mice, they found that chronic pain triggers the output of HDAC4 in dorsal horn neuron nuclei, thereby inactivating it .
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Improve dry eye by regulating hormone levels
Time of Update: 2022-04-26
Loss of sex steroid hormones produced by 3-hydroxysteroid dehydrogenase (3-HSD) causes this condition, but it can be treated with nicotinamide mononucleoside, a new study led by researchers at Kyoto University reports.
"Indeed, disturbed 3-HSD enzyme activity in mutant mice leads to gland atrophy, which further contributes to disease," concludes Doi .
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Spironolactone unlikely to be associated with increased cancer risk
Time of Update: 2022-04-26
"While the FDA warns that "unnecessary use of this drug should be avoided, our data are encouraging that spironolactone is unlikely to be associated with a meaningful prescription at clinical doses" cancer risk,” said senior author John Barbieri, MD, MBA in Dermatology .
"article titleAssociation of Spironolactone Use With Risk of Cancer A Systematic Review and Meta-analysis
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History of spontaneous abortion associated with risk of gestational diabetes
Time of Update: 2022-04-26
Yan Zhao from Tongji University in Shanghai and colleagues assessed whether a history of SAB or induced abortion is associated with an increased risk of gestational diabetes in subsequent pregnancies .
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eLife: Mixing between populations may contribute to HIV transmission
Time of Update: 2022-04-26
"To curb the spread of new HIV infections, we need to better understand HIV transmission patterns in the region," said lead author Lerato Magosi, a postdoctoral fellow at the Center for Infectious Disease Dynamics at the Harvard Chan School of Public Health in Boston, USA .
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Low blood folate levels may be linked to increased risk of dementia and death in older adults
Time of Update: 2022-04-26
Low blood levels of folic acid (vitamin B9) may be associated with an increased risk of dementia and death from any cause in older adults, according to a study published online in the journal Evidence Based Mental Health .
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Mouse study finds nanoparticles reduce skin and lung scarring in scleroderma
Time of Update: 2022-04-26
The findings, published in the journal JCI Insight, show that PLG specifically targets MARCO+ inflammatory cells and prevents skin and lung fibrosis .
While PLG nanoparticles reduced fibrosis in mouse models, Varga said future studies are needed to determine how it prevents MARCO+ activation .
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The 'smell' of an alarm: Volatile chemical signals from damaged plants alert neighbors to herbivore attack
Time of Update: 2022-04-26
Simply put, if mint leaves are damaged after being attacked by herbivores, plants near them activate their anti-herbivore defense systems in response to chemical signals released by damaged mint leaves .
Sustained defense response via volatile signaling and its epigenetic transcriptional regulation .
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Metastatic prostate cancer on the rise as cancer screenings decline
Time of Update: 2022-04-26
A new study from Keck Medicine at USC has found a significant increase in the incidence of metastatic prostate cancer in men 45 and older, in line with recommendations against routine prostate cancer screening .
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Childhood trauma and genes linked to increased obesity risk
Time of Update: 2022-04-26
"Our analysis showed a steady rise in body mass index for each ACE a person experienced, suggesting a very strong and significant link between the number of adverse childhood experiences and adult obesity," said DRI lead author Karen Schlauch Dr.
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Experts find differences in the brains of young children with binge eating disorder
Time of Update: 2022-04-26
"In children with binge eating disorder, we found abnormalities in the development of regions of the brain that are associated with reward and the ability to impulsively or inhibit reward," said Stuart Murray, Della's Department of Psychiatry and Behavioral Sciences at the Keck School of Medicine of USC.
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Sleep apnea accelerates aging, but treatment may reverse it
Time of Update: 2022-04-26
"Cortese's team studied 16 adult non-smokers diagnosed with obstructive sleep apnea and compared them with 8 non-smoking controls to assess the effect of OSA on epigenetic age acceleration over one year .
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PLoS Medicine presents new view: weight loss does not improve pregnancy odds
Time of Update: 2022-04-26
"obesity and pregnancyThe FIT-PLESE study was conducted at nine academic medical centers across the country, and researchers divided participants into two groups: Half of the women were on a high-intensity diet with meal replacements, medication, and increased physical activity .
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Stealth nanodrugs fight cancer, reduce toxic effects of chemotherapy
Time of Update: 2022-04-26
A world-first study conducted by the University of South Australia has determined that frequently used chemotherapeutic drugs (5-FU or fluorouracil) are effective in targeting tumors (rather than surrounding tissue) when optimized liposome formulations are used.
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Endless Forms Are Most Beautiful: Why Evolution Loves Symmetry
Time of Update: 2022-04-25
As they report in the Proceedings of the National Academy of Sciences (PNAS), the emergence of symmetric and other simple structures is so common because evolution has an overwhelming preference for simple "algorithms" -- that is, to produce Structured simple instruction set or recipe .
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Headache nature predicts ischemic stroke
Time of Update: 2022-04-25
Image: Researchers categorized the different headaches experienced by the two groups of patients in the year prior to admissionSource: UrFU / Polina PogrebitskayaScientists from the Ural State Medical University, the Ural Federal University and the University of Copenhagen have developed new criteria for diagnosing headaches caused by ischemic stroke .
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Regular exercise and a healthy diet can increase your odds of surviving cancer and reduce your risk of recurrence
Time of Update: 2022-04-25
The latest edition brings together a decade of data and evidence demonstrating that regular physical activity and a healthy diet are the two most important modifiable factors affecting the long-term health of cancer survivors .
