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Discovery of new mechanisms for regulating blood lipid homeostasis, confirming new targets for lipid-lowering drugs
Time of Update: 2021-10-19
Discovery of new mechanisms for regulating blood lipid homeostasis, confirming new targets for lipid-lowering drugs Discovery of new mechanisms for regulating blood lipid homeostasis to confirm new targets for lipid-lowering drugs Schematic diagram of ASGR1 regulating lipid homeostasis https://doi.
1172/jci.
insight.
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Chinese scientists reveal Venezuelan equine encephalitis virus binding receptor mechanism
Time of Update: 2021-10-19
It is worth noting that the researchers found that the mutation of amino acid at position 41 of LDLRAD3-D1 can increase the binding ability of the receptor to the virus by about 10 times, and has the potential to be a highly effective inhibitor of VEEV .
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Who is the inventor of the concept of chromatography?
Time of Update: 2021-10-19
In 1906, Tswett proposed the concept of chromatography when studying the separation of plant pigments; when he was studying the pigment composition of plant leaves, he poured the extract of plant leaves into an upright glass tube filled with calcium carbonate, and then added petroleum ether to make it flow freely.
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Parkinson's treatment usher in new hope
Time of Update: 2021-10-19
Corresponding author of the paper, Aryn Gittis, associate professor of biological sciences at the school, said that this new study may change this situation .
But the Gittis team has succeeded in mice using a new DBS protocol that uses short-pulse electrical stimulation .
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Propose new strategies for early treatment of osteoarthritis
Time of Update: 2021-10-19
Propose new strategies for early treatment of osteoarthritis Propose a new strategy for the treatment of early osteoarthritis Propose a new strategy for the treatment of early osteo
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Are you ready for the "winter swimming"?
Time of Update: 2021-10-19
" In this study, Scheele and collaborators studied whether Scandinavian winter swimming is related to changes in body temperature and made winter swimmers more adaptable to cold and heat .
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Brain implants promise to treat depression
Time of Update: 2021-10-19
To help Sarah, the Scangos team first recorded the electrical activity of 10 different parts of her brain, and she also reported her emotions for 10 days .
In Sarah's case, the stimulation reduced the right VC/VS activity, thereby suppressing the gamma brain waves in the right amygdala .
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Is the child's visual perception still developing before the age of 10?
Time of Update: 2021-10-19
Shenzhen Advanced Institute and others discovered the different development characteristics of children's overall topological perception in the central and peripheral vision Is the child's visual perception still developing before the age of 10?
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The role of immunotherapy combined with chemotherapy in triple-negative breast cancer revealed
Time of Update: 2021-10-19
By comparing the dynamic changes of immune cells in the chemotherapy group and the combination drug group, the researchers found that in contrast to the combination drug, paclitaxel single-agent chemotherapy can significantly reduce the response to CXCL13+ T cells in the tumor microenvironment of the patient, and cause macrophages with immunosuppressive function.
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Discover a new link between exposure to chemical pollutants and the risk of chronic diseases
Time of Update: 2021-10-19
Exposure group-metabolome association studies clarify the association between environmentally-derived chemicals and chronic diseases and related mechanisms from the perspective of metabolism, provide in-depth etiological understanding for the occurrence and development of diseases, and help early detection and warning of diseases Identification of markers .
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New nano-drugs are expected to prevent Alzheimer's disease
Time of Update: 2021-10-19
Therefore, it is possible to develop an antioxidant multi-target nanomedicine that can efficiently cross the blood-brain barrier and adjust the drug delivery strategy according to different degrees of oxidative stress levels to achieve the prevention and treatment of Alzheimer's disease .
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Middle-age iron deficiency increases the risk of heart disease
Time of Update: 2021-10-19
After adjusting for age, gender, smoking, cholesterol, blood pressure, diabetes, body mass index, and inflammation, the researchers analyzed the relationship between iron deficiency and coronary heart disease, stroke, cardiovascular disease mortality, and all-cause mortality .
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Fish maw is expected to become a new type of vascular material
Time of Update: 2021-10-19
However, the calibers of autologous veins and host blood vessels are usually asymmetry, and it is particularly important to develop suitable new vascular materials .
Test results in animal arterial and venous systems show that swim bladder supports endothelial cell migration and proliferation in vitro and in vivo, and can significantly inhibit intimal hyperplasia .
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Gemini virus promotes viral infection through autophagy factors
Time of Update: 2021-10-19
In order to further analyze the pathogenic mechanism of geminiviruses, the team screened the host protein that interacts with the geminivirus virulence factor βC1, and found that the selective autophagy receptor NBR1 is related to the Chinese tomato yellow leaf curl China virus (Tomato yellow leaf curl China virus).
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Scientists reveal a new mechanism for cell renewal quality control
Time of Update: 2021-10-19
The collaborative team combined the gastric organoid system with single-organ metabolic mass spectrometry analysis to analyze that Helicobacter pylori interferes with the renewal of gastric epithelial cells Quality chemical modification revealed that lysine at position 66 of the cell division spindle plasticity regulation machine EB1 is the physiological substrate of TIP60.
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New progress in research on the effects of organic pollutants on the blood-brain barrier
Time of Update: 2021-10-19
Bromophthalate (TBPH) was the object, and its ability to penetrate the blood-brain barrier and its effect on the structure and function of the blood-brain barrier were studied, and the resulting neurotoxic effects were evaluated .
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How are B cells screened in the meninges
Time of Update: 2021-10-19
How are B cells screened in the meninges How are B cells screened in the meninges? How are B cells screened in the meninges? Schematic diagram of meningeal B lymphocyte developme
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The first tumor cell protein map drawn
Time of Update: 2021-10-19
Trey Ideker of the University of California, San Diego, and colleagues completed this map, studying the interaction of dozens of common cancer proteins in breast and head and neck cancers .
(Source: China Science News Wen Lele) Related paper information: https://doi.
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Listening to Mozart can cure epilepsy
Time of Update: 2021-10-19
Scientists hypothesized that just listening to K448 for 30 seconds may activate the brain's network that is related to the positive emotional response to music and is regulated by the prefrontal lobe .
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Cut off the source of infection: be alert to the new recombinant avian influenza virus
Time of Update: 2021-10-19
Wang Xiaoquan, co-corresponding author of the paper and associate professor of the School of Veterinary Medicine of Yangzhou University, introduced that the research team has been relying on the National Laboratory of Avian Influenza Virus (Yangzhou) for a long time to monitor the live poultry market in East China .
