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Analysis of the survey of more than 22 million people shows a 56% increase in cardiovascular risk in patients with autoimmune diseases
Time of Update: 2023-01-07
Yimaitong edited and sorted, please do not reprint without authorization. Recently, in the top medical journal Lancet. , a survey included more than 22 million people analyzing the cardiovascular risk
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Is it reliable for patients with rheumatoid arthritis to stop methotrexate? Research Express
Time of Update: 2023-01-07
In this context, Dr. Meng and his collaborators of Cornell University conducted the first systematic literature review to evaluate whether MTX can be sustained in patients with RA who achieve remission with MTX plus bDMARDs/tsDMARDs. The results of the study were recently published in the journal J Rheumatol.
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Review and prospects: Combining the three major guidelines to see the progress of the treatment of neuropsychiatric lupus The latest review
Time of Update: 2023-01-07
The 2020 Chinese Guidelines for the Diagnosis and Treatment of Systemic Lupus Erythematosus4 proposed that for patients with severe NPSLE, it is recommended to first undergo hormonal shock therapy, and cyclophosphamide can be added when the effect is not good.
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Five questions to help you quickly clarify gout management strategies Clinical Q&A
Time of Update: 2023-01-07
However, asymptomatic hyperuricemia patients with blood uric acid < 9 mg/dL and no previous gout attacks do not need to initiate urate-lowering therapy.
However, asymptomatic hyperuricemia patients with blood uric acid < 9 mg/dL and no previous gout attacks do not need to initiate urate-lowering therapy.
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Eight rare polygenic autoinflammatory diseases, one article to obtain the latest progress in clinical manifestations, diagnosis and treatment The latest review
Time of Update: 2023-01-07
This review will review recent advances in the clinical manifestations, diagnosis, and treatment of polygenic autoinflammatory diseases1, including Schnitzler syndrome, adult Still's disease (AOSD), SAPHO syndrome (synovitis, acne, impetigo, bone hypertrophy, osteomyelitis), chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO), and Behcet's disease (BD), NOD2-related autoinflammatory diseases (YAOS), PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and lymphadenitis).
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Interpretation of immune cytokines: the role of IL-18 and drug research progress A recent review
Time of Update: 2023-01-07
Fig. 1 Cell source and signal transduction mechanism of interleukin 18 Monoclonal antibodies and drugs targeting IL-18 Given IL-18's role in inflammation, targeting IL-18 appears to be a potential treatment.
Currently, a single-blind, randomized, placebo-controlled Phase 1 trial of human monoclonal antibody GSK1070806 is underway for inflammatory bowel disease (IBD).
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2022NICE guideline update: key points for the diagnosis and treatment of osteoarthritis Guidelines consensus
Time of Update: 2023-01-07
Joint replacement can be considered for patients with hip arthritis, knee arthritis or shoulder osteoarthritis if they have: ➤Joint symptoms (such as pain, stiffness, decreased function, or progressive joint deformity) seriously affect the quality of life of patients ➤ Non-surgical treatments (e.
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Canker sores old and recurrent? Bad teeth? Beware of lupus finding your door with the latest review
Time of Update: 2023-01-07
Teeth and periodontals In a study in which a large number of cariogenic bacteria (Streptococcus distalis and Streptococcus mutans were detected) in supragingival plaque samples from patients with SLE, it has been noted that caries formation is related to the pH of the patient's saliva and the rate of saliva flow.
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If you drink too much coffee, tea, and wine, will you be prone to rheumatoid arthritis? Research Express
Time of Update: 2023-01-07
To assess the association between intake of specific beverages (coffee, tea, alcohol, and soft drinks) and the risk of RA, researchers from France conducted a prospective study in a large cohort, recently published in Rheumatology (Oxford) (impact factor 7.
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The latest global epidemiological data on systemic lupus erythematosus: the incidence of Chinese group ranks fourth in the world
Time of Update: 2023-01-07
In order to provide comprehensive, concise, objective, less biased and standardized SLE epidemiological data to help improve patient management, Professor Qianjin Lu (corresponding author) of the Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, and his collaborators used the gold standard model for the first time to include 112 studies that met the criteria to estimate the global incidence and prevalence of SLE using the gold standard model.
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Reproductive health guidance for women with vasculitis: consensus on guidelines for family planning, contraception, and fertility protection
Time of Update: 2023-01-07
286), aiming to synthesize the recommendations of the American College of Rheumatology (ACR), the American College of Obstetricians and Gynecologists (ACOG), the European Council of Obstetricians and Gynecologists (EBCOG) and the European Union Against Rheumatism (EULAR) expert group and other literature, to provide reproductive health and pregnancy for vasculitis patients and clinicians Comprehensive guidance on disease management and medication safety.
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Sjogren's syndrome secondary to systemic sclerosis, how should it be diagnosed? Latest roundup
Time of Update: 2023-01-07
Yimaitong edited and sorted, please do not reprint without authorization. Systemic sclerosis (SSc) is an autoimmune disease characterized by manifestations such as pulmonary fibrosis or pulmonary hyp
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ANCA-associated vasculitis has recurred, how to deal with it? Latest roundup
Time of Update: 2023-01-07
Treatment of mild recurrent AAV GPA carries a clear risk of recurrence, so immunosuppressants or immunomodulators should be used in combination with GC in all patients with active disease, regardless of severity.
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Often misdiagnosed as spondyloarthritis? This article knows the clinical manifestations and treatment progress of SAPHO syndrome in the latest review
Time of Update: 2023-01-07
SAPHO syndrome is characterized by sterile inflammatory osteomyelitis, osteohyperostophy, and synovitis primarily involving the anterior chest wall, with acneiform dermatoses and neutrophilic dermatoses, and involvement of the axial joints, sacroiliac joints, and peripheral joints may present with symptoms similar to spondyloarthritis (SpA).
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Personalized treatment for rheumatoid arthritis, the latest research of Nature sub-journal to help!
Time of Update: 2023-01-06
1038/s41467-022-33785-wClick "Read Original" to get more clinical dry goods*For reference by medical professionals only, although symptoms are similar between cases of RA, response to treatment varies greatlyExecutive SummaryOn October 20, a study published in Nature Communications deeply analyzed the molecular regulatory mechanisms of rheumatoid arthritis (RA) and found that there are huge differences in the molecular regulatory functions of different cell subtypes involved in RA.
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2022 ACR essence content highlights, see is earn!
Time of Update: 2023-01-06
*For medical professionals onlyJoin hands with big coffee, learn rheumatism academic feast together!The 2022 American College of Rheumatology Annual Meeting (ACR) was held on November 10~14, Eastern T
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Does systemic lupus erythematosus affect pregnancy attempts?
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time~References:[1] 2020 Chinese guidelines for the diagnosis and treatment of systemic lupus erythematosus▼▼▼Click to read the original article to download the AppFor medical professionals onlyOn the relationship between SLE and pregnancy Systemic lupus erythematosus (SLE) is an autoimmune inflammatory connective tissue disease involving multiple organs in young women.
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Sjogren syndrome, what are the local manifestations?
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time~▼▼▼Click to read the original article to download the AppFor medical professionals onlyOpen the [Clinical Decision APP] and talk to the major diagnosis and treatment guidelines!
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How is xerostomia diagnosed, treated and prevented? 2022 ACR Essence Express There are benefits at the end of the article
Time of Update: 2023-01-06
Figure 1: Dry oral mucosa/erythema care for patients with dry mouth should focus on the complications of xerostomia, particularly those with severe saliva flow deficit.
Figure 1: Dry oral mucosa/erythema care for patients with dry mouth should focus on the complications of xerostomia, particularly those with severe saliva flow deficit.
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Express Potential "first-in-class" therapy! More than $100 million to help bifunctional antibodies enter Phase 3 clinical trials
Time of Update: 2023-01-06
The funds raised will be used primarily to advance its lead project, obexelimab, a bifunctional antibody into a global Phase 3 clinical trial to review the efficacy and safety of this drug in the treatment of immunoglobulin G4-related disease (IgG4-RD).
