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Lupus with hydroxychloroquine, 3 major medication precautions!
Time of Update: 2023-02-02
👇Download the Decision Assistant App and check it anytime, anywhere~References: [1] Drug information: hydroxychloroquine sulfate tablets, Sanofi-Aventis SA, imported drug registration number H20160306; 2021/09/04.
👇Download the Decision Assistant App and check it anytime, anywhere~References: [1] Drug information: hydroxychloroquine sulfate tablets, Sanofi-Aventis SA, imported drug registration number H20160306; 2021/09/04.
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Note! After rheumatology patients are infected with the new crown, identifying these early warnings can save lives
Time of Update: 2023-02-02
*For medical professionals onlyAfter the opening of the new crown epidemic, the situation of rheumatism patients infected with the new crown is worth paying attention to. Written by JeniSince the open
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Can infection also cause rheumatism? Recurrent blood clots should be vigilant!
Time of Update: 2023-02-01
Or do you think of antiphospholipid syndrome (APS)?Sure enough, after multidisciplinary consultation, as a consultant in the rheumatology department, Dr. Shi Lianjie believed that the patient could not rule out the possibility of APS, and stopped the anticoagulation treatment of low molecular weight heparin and tested for relevant antibodies:ACL-IgG 104 CU，ACL-IgA
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Under what circumstances can people with lupus use Titanercept? Two key points of medication!
Time of Update: 2023-02-01
, 80mg/Sinopharm S20210008; Last revision date: 2021/03/09 ▼▼▼Click to read the original article to download the Appfor patients with, and is suitable for adult patients with systemic lupus erythematosus (SLE) who still have high disease activity (such as: anti-ds-DNA antibody positive and low complement, SELENA-SLEDAI score ≥8) and positive autoantibody on the basis of conventional treatment.
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New NBT cell therapy strategies protect patients from antibody-mediated rejection
Time of Update: 2023-02-01
In the next step, human CD64 was overexpressed in B6 B2m−/−Ciita−/−Cd47+ immunocompromisedCd64CD64−−/−+(HIP)[2]iECsCD64, B6 HIP iECs CD64 showed IgG1 Fc capture ability in a concentration-dependent manner, and subcutaneous transplantation experiments in ADCC model Rag-1-deficient mice also confirmedCD64 ability to capture Fc. Cd64-expressing mouse iECs were indeed able to protect against antibody-mediated killing effects.
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This critical disease secondary to lupus, the experts' diagnosis and treatment ideas are too incisive!
Time of Update: 2023-02-01
*For medical professionals onlyFever, abdominal pain, anuria, what kind of wolf?Written by Gui ZhiRecently, the "Friendship Rheumatology Big Coffee to Ward Rounds Season 2" held by Beijing Friendship
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Identification of NBT patient-specific T cell antigens
Time of Update: 2023-02-01
In summary, this paper presents a high-throughput genetic system for the identification of neoantigens recognized by T cells in individuals, realizes unbiased screening specific for T cells of all MHC genotypes, is feasible in large genetic libraries, and exhibits sensitivity and throughput superior to existing methods, especially for neoantigens recognized by CD4+ T cells 。 Original link:https://doi.
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Anti-gout drug benzbromarone, must pay attention to these 8 precautions!
Time of Update: 2023-02-01
👇Download the Decision Assistant App and check it anytime, anywhere~References: [1] Drug information: benzbromarone tablets, Yichang Dongguang Changjiang Pharmaceutical Co.
👇Download the Decision Assistant App and check it anytime, anywhere~References: [1] Drug information: benzbromarone tablets, Yichang Dongguang Changjiang Pharmaceutical Co.
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Latest Advances in the Diagnosis and Treatment of STILL Disease in Adults The latest review
Time of Update: 2023-01-07
IL-1β is a key pro-inflammatory cytokine in the immune mechanism of AOSD, and IL-1β inhibitors are widely used biologics in the treatment of AOSD and supported by a series of clinical trials.
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What is Jaccoud's arthrosis? Joint pain in people with lupus may not be a "accompanying symptom" case sharing
Time of Update: 2023-01-07
Figure 2 Specific clinical manifestations and treatment schedule Case discussion JA occurs in 5% of patients with SLE and rheumatic fever, and only cases have been reported in SS.
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Life is in motion! Summary of exercise recommendations for rheumatoid arthritis in the latest review
Time of Update: 2023-01-07
A growing body of research confirms that exercise therapy is an active and effective treatment that not only relieves pain symptoms in RA patients, effectively improves muscle strength and endurance, but also increases range of motion2.
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Rheumatoid arthritis: Can low-dose corticosteroids be used long-term? Latest roundup
Time of Update: 2023-01-07
Yimaitong edited and sorted, please do not reprint without authorization. Rheumatoid arthritis (RA) is an autoimmune disease with erosive arthritis as the main clinical manifestation, with a high disa
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How are rheumatic patients screened for TB infection? List of the 10 Recommendations of the Latest Chinese Consensus Guide Consensus
Time of Update: 2023-01-07
Patients with rheumatic diseases who need long-term use of anti-rheumatic drugs (such as leflunomide, methotrexate, cyclosporine, cyclophosphamide, mycophenolate mofetil) with high risk of tuberculosis activities, and those with conditions are recommended to screen for LTBI (1D).
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Vitamin C to prevent gout, is it a rumor? Research Express
Time of Update: 2023-01-07
Conclusion of the study In this group of male physicians, vitamin C supplementation of 500 mg/day was found to be associated with a lower risk of new-onset gout, suggesting that vitamin C may prevent gout, while vitamin E supplementation has no effect on preventing gout.
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Seven recent rheumatology and immunology guidelines/consensus at a glance Summary of July-September guidelines
Time of Update: 2023-01-07
On August 11, the "Consensus Statement on Blocking Interleukin-6 Receptors and Interleukin-6 under Inflammatory Conditions: Recent Progress" was released, based on the latest evidence and expert opinions, it gave guidance and recommendations on the clinical application of IL-6 inhibitors, covering nine diseases including rheumatoid arthritis, polyarticular course and systemic juvenile idiopathic arthritis, giant cell arteritis, Takayasu arteritis, and adult STILL.
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Monkeypox can also induce arthritis! The Lancet publishes the first case on World Arthritis Day
Time of Update: 2023-01-07
In June, the Chinese Journal of Infection Control published the Guidelines for the Diagnosis and Treatment of Monkeypox (2022 Edition) to improve clinicians' ability to identify monkeypox early and standardize diagnosis and treatment.
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Focus on ankylosing spondylitis, starting with "early detection" on World Spine Day
Time of Update: 2023-01-07
Understand the manifestations of ankylosing spondylitis and strive for early detection Ankylosing spondylitis has an insidious onset, and patients generally gradually develop low back or sacroiliac pain and/or stiffness, may wake up in the middle of the night, difficulty turning over, and lower back stiffness is obvious when rising in the morning or standing up after sitting for a long time, but it decreases after activity.
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How to properly use hormones for ANCA-associated vasculitis? Clinically essential
Time of Update: 2023-01-07
The LoVAS study included patients with new-onset non-severe AAV to assess the clinical prognosis of remission rate, remission time, recurrence rate, and adverse events of two remission-inducing regimens: rituximab combined with low-dose (0.
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Eight rare polygenic autoinflammatory diseases, one article to obtain the latest progress in clinical manifestations, diagnosis and treatment The latest review
Time of Update: 2023-01-07
This review will review recent advances in the clinical manifestations, diagnosis, and treatment of polygenic autoinflammatory diseases1, including Schnitzler syndrome, adult Still's disease (AOSD), SAPHO syndrome (synovitis, acne, impetigo, bone hypertrophy, osteomyelitis), chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO), and Behcet's disease (BD), NOD2-related autoinflammatory diseases (YAOS), PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and lymphadenitis).
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Latest Release! A quick overview of the 17 recommendations of the clinical practice guidelines for enthesitis in patients with spondyloarthritis in China Guidelines consensus
Time of Update: 2023-01-07
It is conditionally recommended not to use x-rays during the evaluation of enthesitis in patients with SpA (level of evidence: moderate)X-rays can only show chronic structural changes, do not provide information about acute inflammatory lesions such as enthesis edema, thickening, or osteomyelitis, and are less sensitive to detect bone erosion and attachments.
