Lupus with hydroxychloroquine, 3 major medication precautions!

Domestic use in adults includes discoid and systemic lupus erythematosus [1-2].

▍Usage and dosage:

The initial dose is 400 mg daily in divided doses
.
When the efficacy is not further improved, the dose can be reduced to 200 mg to maintain
.
If the response to therapy weakens, the maintenance dose should be increased to 400 mg
daily.
The minimum effective dose should be used, not more than 6.
5 mg/kg/day (calculated from ideal rather than actual weight) or 400 mg/day, or even less
.

FDA usage in adults includes adult systemic lupus erythematosus and chronic discoid lupus erythematosus [3-4].

▍ FDA Dosage:

The recommended dose is 200 mg once daily, or 400 mg once daily or divided doses
.

Because this tablet cannot be crushed or divided, the product cannot be directly used in pediatric patients weighing less than 31 kg [3-4].

Treatment of simple malaria in children weighing ≥ 31 kg: initial administration of 13 mg / kg (up to 800 mg); 6.
5 mg/kg (up to 400 mg, total dose = 31 mg/kg - up to 2000 mg) 6 hours, 24 hours, and 48 hours after the first dose.

The safety and efficacy of hydroxychloroquine in the treatment of children with rheumatoid arthritis, chronic discoid lupus erythematosus, or systemic lupus erythematosus have not been established [3-4].

(1) Each dose should be eaten or drunk at the
same time.

(2) Do not crush or break the tablets
.

(3) hydroxychloroquine has a cumulative effect and takes several weeks to exert its beneficial effects, while minor adverse reactions may occur relatively early
.
If there is no improvement in the treatment of rheumatic diseases for 6 months, treatment
should be discontinued.
In photosensitive diseases, treatment should be given
only with maximum exposure to sunlight.

Can people with psoriasis use hydroxychloroquine?

What are the symptoms of hydroxychloroquine overdose?

How to deal with it?

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