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Nat Commun: Why are cancer immunotherapy ineffective in young women?
Time of Update: 2020-09-07
(Photo source: www.pixabay.com) their findings suggest that because young and female patients often have stronger immunity to better remove tumor cells, the cells left behind are initially less undetectable to the immune system, making certain types of immunotherapy ineffective.
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These 4 skills may help children cope with the anxiety caused by COVID-19.
Time of Update: 2020-09-07
August 19, 2020 // -- The current news about COVID-19 is so great that, while experiencing the popularity of COVID-19 can be difficult, it may be much easier for educated adults than for children, who
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Science: Reveals the mechanism by which therapeutic antibodies bind to human CD20.
Time of Update: 2020-09-07
August 18, 2020 /--- Since the late 1990s, immunotherapy has been the first line of treatment to combat lymphoma, using synthetic antibodies to prevent the proliferation of cancerous white blood cells.
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Cell Host and Microbe Interpretation! Experimental vaccines may be effective in preventing SARS-CoV-2 infections!
Time of Update: 2020-09-07
August 19, 2020 // -- A recent study published in the international journal Cell Host and Microbe entitled "Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis in mice" In the report, scientists from the University of Washington School of Medicine and others said an experimental vaccine could effectively prevent pneumonia in mice infected with the SARS-CoV-2 virus, which is made from a mild virus genetically modified to carry key genes from the SARS-CoV-2 virus.
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Science: Reveals that patients with severe COVID-19 experience immune system paralysis.
Time of Update: 2020-09-07
August 18, 2020 /--- In a new study, researchers from Stanford University, Emory University and the University of Hong Kong in China and the Hong Kong Hospital Authority found that in severe COVID-19 patients, "first responders" immune cells that respond immediately to signs of viruses or bacteria in the body are slow to respond.
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Science: Reveals the mechanism by which protein BAF prevents cells from attacking their own DNA.
Time of Update: 2020-09-07
, "So we can conclude that BAF plays a key role in preventing cells from attacking their DNA." " inhibition of this protein is extremely important: while the cGAS-STING approach helps the body fight infection, it also needs to be controlled.
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The study reveals the mechanism by which fish regulates the natural immune response to antivirals.
Time of Update: 2020-09-07
On the basis of clarifying the natural immune response mechanism of fish antivirals, using natural immune response negative regulatory factors as molecular targets and using gene editing technology to cultivate new species of disease-resistant fish is an important direction for the development of aquaculture industry.
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Age-related injuries were reversed in mouse models.
Time of Update: 2020-09-06
immune cells in belly fat play a key role in regulating chronic low inflammation and aging-related processes, the researchers report.
that eosinophil therapy promotes youth, the researchers looked at the possibility of reversing age-related damage by restoring the stability of immune cells in visceral adipose tissue.
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The first human melanoma RNA vaccine may be expected to treat advanced melanoma.
Time of Update: 2020-09-06
In the exploratory interim Bradbrook/Springer Nature Limited study, researchers analyzed 89 patients with advanced melanoma who were given at least eight doses of the FixVac vaccine in at least one of the four TAS-coded TAAs. Doses of RNA ranged from 7.2ug to 400ug, and some patients continued to be given monthly boosters, with some study queues receiving only FixVac and others receiving ICC treatment targeting PD1.
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The new use of old medicine shows god effect! Can statins really be used to treat SARS-CoV-2 infections?
Time of Update: 2020-09-06
August 21, 2020 // -- Now that scientists around the world have made unprecedented efforts to respond to the COVID-19 pandemic, researchers have been able to find effective ways to quickly and effecti
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Nat Commun: Targeted therapy overcomes cancer tolerance.
Time of Update: 2020-09-06
"s study suggests that the combination of targeted OSMR genes and radiation therapy could pave the way for future clinical trials to better treat glioblastoma tumors.
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New drug for rheumatoid arthritis! Gilead JAK inhibitor filgotinib was rejected by the FDA, $80 million to buy the coupon into a bubble!
Time of Update: 2020-09-06
The European Union, at the end of July this year, the European Medicines Agency (EMA) Human Pharmaceutical Products Committee (CHMP) issued an active review recommending the approval of Jyseleca (filgotinib, 100mg and 200mg tablets) for the treatment of moderate to severe RA adult patients who do not respond well to one or more disease-modified rheumosic drugs (DMARD).
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Lancet sub-journal: Antibiotic use or directly associated with an increased risk of inflammatory bowel disease in individuals.
Time of Update: 2020-09-06
19, 2020 // -- In a recent study published in the international journal The Lancet Gastroenterology and Hepatology, scientists from the Caroline Institute in Sweden and other institutions found that the use of antibiotics (especially more widely available antibiotics, broad-spectrum antibiotics) or increased risk of new inflammatory bowel disease (IBD) and its subtypes of ulcerative colitis and crohn's disease in the population was directly related.
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Read it in depth! Cardiovascular disease may be closely related to cancer!
Time of Update: 2020-09-06
August 21, 2020 // -- Researchers are now slowly realizing that the systemic environment of the host body may promote cancer progression and be affected by cancer, but our understanding of this intera
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Int J Cancer: Scientists are expected to use a multigene risk scoring system to predict the risk of common cancers in the population.
Time of Update: 2020-09-06
August 19, 2020 // -- Scientists from Vanderburg University and other institutions have made significant progress in cancer prevention research in a recent study published in the international journal International Journal of Cancer entitled "Evaluating polygenic risk scores in assessing risk of nine solids and hematologic cancers in Europeans".
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Nat Struct and Mol Biol: Revealing how DNA polymerases ζ protect cells from DNA damage or hopefully help develop new treatments against drug-resistant cancers.
Time of Update: 2020-09-06
Photo Source: CC0 Public Domain researcher Professor Anel Aggarwal says parsing the structure of the complete Pol ζ enzyme at near-atomic resolution may help researchers solve a long-standing problem of how this particular polymerase replicates through everyday DNA damage events, while also providing researchers with a template to design new drugs for cancers that traditional chemotherapy cannot cure.
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Interpretation! Scientists have discovered four subtypes of triple-negative breast cancer cells that could help develop new individualized targeted therapies.
Time of Update: 2020-09-06
21, 2020 // -- In a recent study published in the international journal EMBO Journal entitled "Stromal cell diversity with immune in human triple-negative breast cancer", scientists from the Gavin Ins
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Cell sub-journal interpretation! Does the bacterial bacterium in breast milk really grow in the baby's intestines?
Time of Update: 2020-09-06
August 21, 2020 // -- Breast milk has a special microbiome, but it is not clear to researchers whether these microbiomes will sow seeds in breastfed infants and change them by breastfeeding, according
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Nat Commun: Scientists hope to combine nanotechnology with genetic engineering to develop new cancer therapies.
Time of Update: 2020-09-06
Photo Source: JAIST In a recent study published in the international journal Nature Communications, scientists from Japan's Institute of Advanced Science and Technology and others combined nanotechnology with genetic engineering called photothermogenetics to develop a regulatory technique for the properties of deadly cancer stem cells, which promotes the effective elimination of cancer in the body.
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5 in 1 meningitis vaccine! GlaxoSmithKline's MenABCWY III Clinical Program vaccinated the first subjects!
Time of Update: 2020-09-05
If GSK's 5-in-1 meningitis vaccine MenABCWY is successful in this Phase III clinical trial, it will be able to help protect adolescents and young people from invasive meningococcal disease (IMD) with fewer injections.