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JEM: New study reveals the pathogenic mechanism of hepatitis B virus.
Time of Update: 2020-09-09
(Photo source: www.pixabay.com) To improve understanding of antibody response responses to HBV infection, scientists at the Pasteur and Inserm Institute, in collaboration with the Roche Innovation Center in Switzerland, isolated memory B cells from the blood of HBV vaccinators and naturally recovered patients, and produced and identified monoclonal antibodies against viral membrane antigens (HBsAg).
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PNAS: Identifying new potential targets for a variety of human cancers is expected to lead to the development of highly effective targeted anti-cancer therapies.
Time of Update: 2020-09-09
August 15, 2020 // -- Many types of human cancers exhibit changes in the balance of kinases and phosphatases, and drugs that inhibit kinase activity are now clinically successfully used as cancer ther
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The third innovative drug for optic neuroscolonitis spectrum disorder (NMOSD)! Roche IL-6R monoanti-anti-Enspryng is approved by the FDA!
Time of Update: 2020-09-09
data from two randomized controlled Phase III studies (SakuraStar, SAkuraSky) confirmed that enspryng was used as a monotherapy and baseline in adult patients with AQP4 antibody-positive NMOSD Immunosuppressant (IST, commonly used to manage relapse-related NMOSD symptoms) combined treatment has strong and long-lasting efficacy and good safety: Enspryng significantly reduces the risk of recurrence compared to placebos and lasts up to 96 weeks.
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mBio: Viruses may use a special "bait strategy" to evade attacks by the host immune system.
Time of Update: 2020-09-09
August 16, 2020 // -- In a recent study published in the international journal mBio, scientists from the University of Otago and other institutions used research to reveal how viruses use a bait strategy to evade attacks by the host immune system, and the results may help develop new treatments for COVID-19.
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Cell Rep: Chinese Academy of Sciences Liu Hongwei, Liu Shuangjiang team's latest research results: Reishi derivatives may be expected to help treat non-alcoholic fatty liver!
Time of Update: 2020-09-09
August 15, 2020 // -- In a recent study published in the international journal Cell Reports, scientists from the Institute of Microbiology of the Chinese Academy of Sciences and other institutions reported on the GMD, Ganoderma meroterpene derivatives The anti-non-alcoholic fatty liver disease (NAFLD) effect, the researchers said, GMD can increase the abundance of mycobacterium bacteria to activate the genus Bacillus anthropobacteria-folic acid-liver path, which in turn slows symptoms in patients with non-alcoholic fatty liver disease.
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Nature: How can you effectively slow tumor growth and progress by easily pressing the metabolic switch?
Time of Update: 2020-09-09
By limiting the dietary amino acids serine and glycine, or pharmacologically targeted synthase phosphate glycerine dehydrogenase, researchers can induce tumor cells to produce a toxic lipid that slows the progression of tumors in mouse bodies, and later researchers need to study further to determine whether this method can be converted into clinical patients.
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Cell Rep: Inhibiting special TLK kinases or activating the body's congenital immune system promises to help develop new cancer therapies.
Time of Update: 2020-09-09
August 15, 2020 // -- Tousled-like kinases (TLKs, Tousled-like kinases) play a central role in DNA repair and replication and are expected to be potential therapeutic for scientists to develop new cancer therapies In a recent study published in the international journal Cell Reports, scientists from the Institute of Biomedical Research in Barcelona and others found that inhibiting TLK may activate the body's congenital immune system, which is an important factor in the body's response to cancer.
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Will the cat be infected with SARS-CoV-2? Does it really spread the SARS-CoV-2 virus?
Time of Update: 2020-09-09
There is research evidence that SARS-CoV-2 originated in bats, and now researchers have found that the coronavirus subtype to which the virus belongs has been spreading in bat populations since the 1940s; cats are the most popular pets in the UK, with nearly 10 million cats in homes across the UK, and questions have been raised about whether cats will become infected when tigers and lions at the Bronx Zoo in New York are found to be infected with SARS-CoV-2.
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Cell Res: Breakthrough! Chinese scientists have unveiled the atomic structure of the first EB virus nuclear shell.
Time of Update: 2020-09-09
By developing a new virus growth strategy and using cryoelectrometer technology, researchers can obtain high-quality virus samples of EBV, and then they can determine the high-resolution structure of the EBV nuclear shell and the first complete atomic model derived from it, which includes twenty-faced crusts, crust-related skin complexes (CATCs) and twewevigic portal structures (viral genomic transtation devices).
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JBC: Reveals the molecular mechanisms by which special cell proteins control the spread of cancer.
Time of Update: 2020-09-09
The study raises long-standing questions about scientists' long-held hypothesis that PRL3 plays a key role in cancer diffusion, and the researchers believe that special binding mechanisms may be key to some extent; understanding the mechanisms by which binding to magnesium ion transport proteins, rather than the catalytic activity of enzymes, affects cancer growth and migration signals may hopefully help researchers identify new compounds to prevent cancer from spreading.
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Haematologica: Uncover the key role of co-priced closed ring RNAs in leukemia occurrence or hopefully develop a variety of leukemia targeted therapies.
Time of Update: 2020-09-09
Poor survival prognosis in patients is directly related; recent researchers found that ASXL1 gene bits undergo selective shearing to produce circRNAs, while previous studies of circRNAs have focused on understanding the origins of these non-coding RNAs, in which researchers revealed the key role of circRNAs in regulating the evolutionary genetic blueprint and the effects of circRNAs on hema production development and leukemia.
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PLoS ONE: Cardiovascular risk factors or directly related to complications and mortality in patients with COVID-19.
Time of Update: 2020-09-08
August 17, 2020 // -- In a recent study published in the international journal PLOS ONE entitled "Impact of cardiovascular risk profile on COVID-19 outcome-A meta-analysis", scientists from Italy have found that cardiovascular risk factors may be closely related to complications and death risk in patients with COVID-19.
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Nat Commun: Genetic mutations lead to eczema.
Time of Update: 2020-09-08
August 17, 2020 /--- A recent new study by the National Institutes of Health reveals how two relatively common variants of the KIF3A gene cause skin damage, leading to increased skin moisture loss and promoting eczema.
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Cell Rep: Using Sialyl-LewisX glycoprotein to identify active HIV reservoirs that are hidden during treatment, it lays the foundation for the development of a cure for HIV infection.
Time of Update: 2020-09-08
the authors also found that the expression of a specific algal glycosylated protein called Sialyl-LewisX (SLeX) identifies persistent HIV transcription in the body, and that primary CD4 T cells with high levels of SLeX have higher levels of T-cell pathogenes and proteins known to drive HIV transcription during ART treatment.
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Blood Adv: A new human organ chip has been used to reveal the molecular mechanisms by which ovarian cancer metastasis occurs by the power of plateplates.
Time of Update: 2020-09-08
Photo Source: Currently, researchers at Texas A and M Engineering believe plateplates or ovarian cancer metastasis agents, but they don't know exactly what mechanisms can introduce plateboards into tumor cells, compared to the very difficult study of the mysteries in animal models, in which researchers propose a new solution, the organ chip study.
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Nature: In Phase 1/2 clinical trials, Pfizer's new crown pneumonia mRNA candidate vaccine triggers a powerful immune response in the human body.
Time of Update: 2020-09-08
August 17, 2020 /--- -- In a new study, researchers from Pfizer reported that a candidate vaccine based on cutting-edge RNA gene technology showed signs of strong resistance to the new coronavirus SARS-CoV-2 in an early clinical trial.
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Autoantibodies - the body's own antidepressants.
Time of Update: 2020-09-08
researchers at the Max Planck Institute for Experimental Medicine in Germany have been studying the circumstances under which autoantibodies targeting a specific glutamate-specific subject (NMDA) are formed and their effects on the brain.
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Cell: A new probe that detects the destruction of defective mitochondrials in cells is expected to reveal the pathogenesis of a variety of neurodegenerative diseases.
Time of Update: 2020-09-08
17, 2020 // -- In a recent study published in the international journal Cell, scientists from the Japan Institute of Science and Chemistry and others developed a generic probe that could help accurately detect the procedural damage of defective mitochondrials in cells, which researchers say are energy plants in cells that may not be able to destroy damaged mitochondrial cells in mouse models with Parkinson's disease.
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Scientists have found immune cells that reduce the risk of respiratory allergies and asthma.
Time of Update: 2020-09-08
but most people have immune cells that respond to common allergens, such as HDM, so we don't have allergies.
they found a previously unknown subgeneration of T-cells that control allergic immune reactions and asthma development in response to indoor dust mites and other possible allergens.
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Ann Int Med: Obesity may increase the risk of death in COVID-19 patients, especially young men.
Time of Update: 2020-09-08
AUGUST 17, 2020 // -- In a recent study published in the international journal Annals of Internal Medicine, scientists from Kaiser Medical Center in Southern California and other institutions found a