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PNAS: The Bacillus tuberculosis vaccine is beneficial for the elderly and diabetics.
Time of Update: 2020-09-12
." AITHM researcher Harindra Sathkumara said that when given to older diabetic mice, BCG:: RD1 has been shown to be highly protective, acting not only on T cells but also on other immune cell substations, resulting in a strong response to TB-causing bacteria.
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Regeneron "cocktail" therapy can effectively protect animals and speed up the elimination of viruses
Time of Update: 2020-09-12
In this paper, researchers found that REGN-CoV2, in two animal models, Rhesus Monkeys and Golden Hamsters, was able to rapidly improve the virus's removal rate as a preventive therapy, in addition to rapidly increasing the rate of virus removal after an animal be infected with the new coronavirus, as a preventive therapy to improve the protection of animals, significantly speeding up the subsequent virus removal in the test.
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Sci Rep: Scientists have discovered new symptoms of tuberculosis.
Time of Update: 2020-09-12
team, led by Herman Spaink, a professor of molecular cell biology at Leiden University, studied metabolites (intermediates and end products) produced by TB infection in human and animal models.
most importantly, we can now study the disease extensively in zebrafish larvae, and these results can be translated into humans," he said.
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NASH new drug! Mercadon signed an $870 million agreement with Korea-U.S. Pharmaceuticals to obtain the GLP-1/GL-GL regent double excitator efinopegdutide.
Time of Update: 2020-09-12
August 05, 2020 / / -- Merck Co) and Hanmi Pharma have jointly announced that they have signed an exclusive license agreement for the development, manufacture and commercialization of efinopegdutide (formerly HM12525A), a weekly glutatrogen-like peptide-1 (GLP-1)/GGL) subject dual agonist developed by Hanmi for the treatment of non-alcoholic fatty hepatitis (NASH).
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Clin Infect Dis: Scientists have found the main culprit for the common acute gastroenteritis, the NOra virus of the GII.4 genotype.
Time of Update: 2020-09-11
August 13, 2020 // -- Scientists from Vanderburg University and others have revealed the culprits for acute gastroenteritis in a recent study published in the international journal Clinical Infectious
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Devel Cell: What's new! Oxygen-deprived breast cancer cells may use extracellular follicles to send cancer-causing stimulation signals to normal cells!
Time of Update: 2020-09-11
August 13, 2020 // -- In a recent study published in the international journal Developmental Cell, scientists from the Westa Institute in Philadelphia and other institutions in the United States found
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New drug for fibrosis interstitia pulmonary disease (ILD)! Bringer Ingham Ofev (Nidanib) launches the Pediatrics Global Phase III study!
Time of Update: 2020-09-11
It's worth noting that InPedILD is the world's first clinical trial of ILD for children and adolescents, based on Ofev's Phase III INBUILD trial and regulatory approval for adult patients with aggressive esoteric fibrosis ILD (PF-ILD) to address the unsatisfying and important needs of the most vulnerable pediatric patient population affected by ILD.
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Cell Metabol: Breakthrough! Scientists may be expected to target metabolic changes in acting cells to remove drug-resistant cancer cells!
Time of Update: 2020-09-11
researcher Gastel points out that these changes may not be visible when the cancer begins to relapse late, a short-lived stress response in which cancer cells become very vulnerable if they target the metabolism of cancer cells, and when researchers use only one day to target the metabolism of cancer cells or nucleotides, drug-resistant cancer cells are eliminated and the patient's disease symptoms improve.
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Cell Rep Med: Reveal the key role the immune system plays in the development of severe COVID-19 infections!
Time of Update: 2020-09-11
13, 2020 // -- In a recent study published in the international journal Cell Reports Medicine, scientists from the Caroline Institute in Sweden and other institutions identified a variety of cell types through in-depth analysis of the immune system activation mechanisms of patients with severe COVID-19, which play a key role in the body's immune response to the new coronavirus and the excessive inflammatory response in severe cases.
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Chaos: Why does COVID-19 only affect the function of certain organs in the host body?
Time of Update: 2020-09-11
August 13, 2020 // -- In severe cases of COVID-19, damage not only spreads to lung tissue, but also to other organs, such as the heart, liver, kidneys, and parts of the nervous system, but SARS-CoV-2
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The researchers published a map of single-cell development and heterogeneity in the stable and inflammatory state of neutral granulocytes.
Time of Update: 2020-09-11
Finally, to study the effects of bacterial infection on neutral granulocyte development and sub-groups, the authors isolated the bone marrow, extrinsic blood, spleen and neutral granulocytes of acute perititis mice for single-cell RNA sequencing and analysis.
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Cell: Blocking the function of specific proteins may be expected to enhance the effectiveness of immunotherapy to enhance the ability to remove drug-resistant cancer cells.
Time of Update: 2020-09-11
August 13, 2020 // -- Immunotherapy, which can quickly and completely alleviate the disease of some cancer patients by stimulating the patient's own immune system, has revolutionized the treatment of
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Nat Struct Mol Biol: Study reveals how Zika virus suppresses immune response
Time of Update: 2020-09-10
our work provides valuable structural and functional information on the interactions between the Zika virus and its hosts, as well as a framework for the development of vaccines and antiviral drugs.
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Reinvent the treatment mode! Roche Xolair pre-charged syringe self-injection application accepted by FDA: for all allergies!
Time of Update: 2020-09-10
In the United States, Xolair is currently approved for use by healthcare providers in healthcare facilities and is the only biological agent approved to target block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma and chronic idiotic urticaria (CIU).
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Front Microbiol: New method improves bacteria's sensitivity to antibiotics.
Time of Update: 2020-09-10
AUGUST 14, 2020 /--- In a recent study, researchers at the Massachusetts Institute of Technology's Singapore-based research company, the Singapore-MIT Alliance for Research and Technology (SMART), discovered a new way to reverse the antibiotic resistance of certain bacteria using hydrogen sulfide (H2S).
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FASEB J: Heavy! Scientists have discovered a special protein that could help SARS-CoV-2 spread rapidly in host cells!
Time of Update: 2020-09-10
Ross, a researcher, says cells can react to stress events by making changes in the cellular environment, including modifying certain proteins, but viruses try to evade the cell's defenses and want to infect cells, but sometimes they regulate these pressure particles, which can reduce the host cell's ability to respond to the virus by blocking the cell's normal stress response.
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Interstuming stem cells (MSCs) treat grafts against host disease! Anti-inflammatory cell therapy Ryoncil was approved by a U.S. FDA panel of experts!
Time of Update: 2020-09-10
recently, the company announced that the U.S. Food and Drug Administration's (FDA) Advisory Committee on Oncology And Drugs (ODAC) voted overwhelmingly (9 in favor, 1 against) to support the effectiveness of the allogeneic cell therapy Ryoncil (remestemcel-L) for the treatment of childhood steroid incurable acute graft anti-host disease (SR-aGVHD).
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Nat Genet: HPV subsypes may affect treatment and prognostication in patients with cervical cancer.
Time of Update: 2020-09-10
14, 2020 // -- In a recent study published in the international journal Nature Genetics, scientists from the University of British Columbia and others analyzed women with cervical cancer in Uganda and found that there may be significant genomic differences between tumors caused by different human papillomavirus (HPV), suggesting that the type of HPV may affect the disease characteristics and treatment prognosis of cervical cancer patients.
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Cell Rep: Identify a key protein that regulates the estrogen cycle in a female body, RSK2.
Time of Update: 2020-09-10
August 14, 2020 // -- Scientists from Vanderburg University and others have discovered a key regulatory protein that regulates the body's estrogen cycle in a recent study published in the internationa
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Chem: Understanding the surface chemistry of SARS-coV-2 contributes to vaccine development.
Time of Update: 2020-09-10
August 14, 2020 /--- Based on a recent study, we need to better understand the surface chemical characteristics of the SARS-CoV-2 virus to reduce transmission and accelerate vaccine design.