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Lancet Rheumato: Study on the safety of hydroxychloroquine for the treatment of rheumatoid arthritis.
Time of Update: 2020-09-24
combination of hydroxychloroquine and azithromycin increased the risk of cardiovascular mortality (2.19), chest or angina (1.15) and heart failure (1.22) for 30 days.
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The gospel of rheumatoid arthritis patients in China! Adamu mono-resistant biosygen SULINNO has been approved for listing in China.
Time of Update: 2020-09-24
Innovent Biologics announced today that SULINNO® (Recombinant human anti-TNF-alpha monoclonal antibody injection, Adamo monoantigen) has been officially approved by China's State Drug Administration (NMPA) for the treatment of rheumatoid arthritis, strong straightening spina bifida and psoriasis.
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Gastroenterology: Hormone therapy increases the risk of severe neo-coronary pneumonia infection in patients with inflammatory bowel disease.
Time of Update: 2020-09-24
SECURE-IBD study, data on IBD patients with new coronavirus infections were collected, age-standardized mortality rates were calculated in IBD patients, and multivariable logic regression was used to identify factors associated with severe Covid-19, including intensive care unit hospitalization, ventilator use, and/or death.
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Pediatr Obes: Increased physical activity time reduces the risk of metabolic syndrome.
Time of Update: 2020-09-24
moderate to high-intensity physical activity, sedentary time was independent of metabolic syndrome .OR 1.14 95% CI 0.96-1.36.
, the results showed that moderate and above intensity of physical activity, rather than sedentary time, was independently associated with metabolic syndrome.
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Acta Neuropathologica: The 375-bit phosphate-resistant anti-TDP-43 antibody of serine indicates a difference in the composition of the TDP-43 aggregate between FTLD-TDP subtypes.
Time of Update: 2020-09-24
ALS-TDP's TDP-43 pathology, FTLD-TDP B (including cases of C9orf72 mutation) and FLD-TDP C all showed strong pTDP-43S375 immune response, similar in number and morphology to the gold standard with S409/410 phosphate antibodies.
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Ann Rheum Dis: Relationship between psoriasis, psoriasis arthritis and osteoporosis.
Time of Update: 2020-09-24
study, published in Ann Rheum Dis, used 432,513 samples from biobanks in the UK to assess the relationship between psoriasis/psoriasis arthritis (PsA) and estimated bone density (eBMD)/osteoporosis using multifaceted linear/logistic regression.
, MR analysis showed no causal relationship between psoriasis/PsA and eBMD, osteoporosis and fractures.
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Blood: The efficacy and safety of Mavorixafor's treatment of WHIM syndrome.
Time of Update: 2020-09-18
Central point: THE use of mavorixafor (400 mg, oral, 1/day) in WHIM patients increased the total number of white blood cells, neutral granulocytes and lymphocyte counts; summary: Warts, hypoproglobulinemia, infection and myelin anemia syndrome (WHIM) are rare primary immunodeficiencys caused by mutations in the function of the CXCR4 gene.
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JNNP: The Origin of Seizures of Autoimmune Diseases: A Multi-Center Retrospective Study.
Time of Update: 2020-09-18
ADE2 score (median 5, range 1-15) was significantly associated with antibody-positive rates (p - 0.014), especially for neuropsychiast symptoms (p .lt;01), movement disorders (p .
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A new immune subject of plant-perceived lynx polymorphism whiplash has been revealed.
Time of Update: 2020-09-13
experts say the study is the first to reveal the allegiance variants in soybeans that identify bacteria polymorphic whiplash, and proves that the identification of this polymorphic whiplash protein can enhance plant disease resistance and provide a new strategy for improving crop resistance to bruising bacteria.
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Science Subpic: Reveals why immunity declines in older adults and suggests that lowering Tfh10 cell levels is expected to make vaccines more effective for older adults.
Time of Update: 2020-09-13
!--webeditor: page title" -- August 4, 2020 // --- Many people understand that our immune system weakens with age, which partly explains why older people tend to receive less protection from the annua
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Nat Commun: A new mechanism for phages to kill bacteria.
Time of Update: 2020-09-12
what they saw was the incredible "arrangement" that phages produce when they assemble the main components of their particles: a head full of viral DNA and a tail for infecting bacteria.
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PNAS: Key mutations in the Zika virus promote its spread.
Time of Update: 2020-09-12
(Photo: www.pixabay.com) In this study, researchers identified mutations in Zika's envelope protein that increase mother-to-child transmission in pregnant mice, increase neurological disease and mortality in newborn mice, and increase the level of viruses in the blood of infected non-human primates.
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Long-term symptoms and complications of COVID19.
Time of Update: 2020-09-12
" (Photo: www.pixabay.com) According to Dr. Poland, coVID-19 patients may have long-term and persistent complications.
"Some symptoms may have long-term effects on patients with asymptomatic or mild COVID-19," Dr. Poland said.
(bioon.com) Source: Long-term symptoms, complications of COVID-19.
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Nature: Antioxidant-rich foods such as black tea, chocolate, and berries may increase the risk of colorectal cancer.
Time of Update: 2020-09-12
researcher Ben-Neriah said the gut bacteria appear to play a dual role in the mutant p53 protein, which in small intestine tissue can completely change its orientation and begin to attack cancer cells, while in colon tissue it promotes the growth of cancer cells.
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Cell Rep: Multi-group studies reveal the detailed characteristics and heterogeneity of HIV-1 infected cells.
Time of Update: 2020-09-12
August 6, 2020 // -- In order to eliminate HIV infection, it is important to clarify the detailed characteristics and heterogeneity of HIV-1 infected cells in the body, a recent study published in the international journal Cell Reports, scientists from the University of Tokyo and other institutions said that the use of genetically modified HIV-1 to infect human-based mouse models of hematopoietic stem cell transplants or hopefully reveal in the body the characteristics of cells producing HIV-1.
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PNAS: The key to regulating the inflammatory response of tissues.
Time of Update: 2020-09-12
they believe the findings will provide the basis for future studies of the role of skeletal muscle residering macrophages in skeletal muscle diseases, such as muscular dystrophy, and muscle damage.
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Overweight pounds! The world's first hepatitis B treatment drug: Hepcludex is approved for sale in the European Union, the treatment of hepatitis B in Phase II clinical!
Time of Update: 2020-09-12
I am pleased that, after more than 20 years of scientific and clinical research, liver cells entering the inhibitor Myrcludex B, now Hepcludex, which can be used in patients, the approval of the drug on the market will significantly improve their lives.
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Inflammatory bowel disease (IBD) new drug! Roche's double-acting anti-integration therapy etrolizumab Phase III clinical project: the results have been mixed!
Time of Update: 2020-09-12
August 11, 2020 // -- Roche's Gene Tek recently announced the top-line results of a phase III research project evaluating the treatment of ulcerative colitis (UC) in etrolizumab. results of four doub
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Lilly launches phase III clinical trial of new coronavirus and antibody.
Time of Update: 2020-09-12
Like the new crown vaccine, antibody-based new crown drugs are advancing at an unprecedented rate. antibody drugs have the potential to help prevent new coronavirus infections and treat COVID-19 in o
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Regeneron "cocktail" therapy can effectively protect animals and speed up the elimination of viruses
Time of Update: 2020-09-12
In this paper, researchers found that REGN-CoV2, in two animal models, Rhesus Monkeys and Golden Hamsters, was able to rapidly improve the virus's removal rate as a preventive therapy, in addition to rapidly increasing the rate of virus removal after an animal be infected with the new coronavirus, as a preventive therapy to improve the protection of animals, significantly speeding up the subsequent virus removal in the test.
