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    Home > Active Ingredient News > Immunology News > A new immune subject of plant-perceived lynx polymorphism whiplash has been revealed.

    A new immune subject of plant-perceived lynx polymorphism whiplash has been revealed.

    • Last Update: 2020-09-13
    • Source: Internet
    • Author: User
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    The study by Alberto Macho of the Shanghai Center for Plant Adversity Biology at the Center for Excellence and Innovation in Molecular Plant Science of the Chinese Academy of Sciences reveals that soybeans have evolved a lithum-sensing polymer protein, a classic example of plant-bacterial co-evolution.
    published online July 28 in nature-newsletter.
    plant diseases caused by bacterial pathogens are an important factor threatening world food security.
    The pathogen of plant bruising disease, the bruising bacteria, can infect more than 250 plants in 50 departments, including some important food crops, such as potatoes, tomatoes, tobacco, bananas, green peppers and eggplants, resulting in huge economic losses.
    plant immune system is able to detect conservative bacterial pathogen molecules and initiate an immune response to suppress disease.
    is the most widely studied bacterial pathogen molecule and is the component that forms bacterial whiplash.
    although most bacteria's whiplash proteins can be identified by plants and stimulate an immune response, the whiplash proteins of chrystosis bacteria have undergone polymorphic changes, successfully avoiding the identification of conventional receptors in plants.
    compared with pathogenic fflg22, there are 9 polymorphic bits in the Fpg22 table and can evade the identification of athropomorphic mustard and tobacco. the crystal structure of
    pathogenic flog22 and the athropomorphic mustard FLS2/BAK1 receptor has been analyzed, and according to the known structural information, the study carried out the modeling of the congenital structure and the analysis of the fixed-point mutation, and determined that the polymorphism of 18-21 amino acids in the flg22 of the chrysanthemum bacteria played a key role in avoiding immunity.
    more interesting, the study was the first to find that soybeans were able to identify the polymorphism of the syndicate fleg22 and successfully identified the syndicate fleg22 subject GmFLS2/GmBAK1.
    the same time, the researchers modeled the yrobial fling22/GmFLS2/GmBAK1 structure according to the known ffl22/AtFLS2/AtBAK1 ternial structure, and locked the important bits of soybean subject identification, GmFLS2-Q368 and GmFLS2-R483.
    addition, the study found that the expression of GmFLS2/GmBAK1 can enhance the resistance of tomatoes to lycoper, and has good application prospects.
    experts say the study is the first to reveal the allegiance variants in soybeans that identify bacteria polymorphic whiplash, and proves that the identification of this polymorphic whiplash protein can enhance plant disease resistance and provide a new strategy for improving crop resistance to bruising bacteria.
    In addition, revealing the key residuals responsible for escaping and acquiring perception in GmFLS2 in flog22 provides guidance for synthetic biology methods to customize immune subjects and expand the range of subject identification, making it possible to identify motivators of polymorphic pathogens.
    the first author of this paper, Alberto Macho Research Group Ph.D. student Wei Yali is understood to be the first author of this article, Alberto Macho researcher is the communication author of this article.
    the research was supported by the Chinese Academy of Sciences and the National Natural Science Foundation of China.
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