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New anti-transplant drugs! IL-2 Receptor Targeting Immunotherapy Leukotac is on the market in the United States, significantly prolonging patient survival!
Time of Update: 2020-07-31
July 24, 2020 /PRNewswire/ -- Elsaly Biotech, a subsidiary of Mediolanum Farmaceutici Spa, recently announced that the U.S. Food and Drug Administration (FDA) has agreed to initiate the submission process for leukotac biological product licensing application (BLA) for the treatment of patients with SR-aGvin disease in the class II-IV steroid refractive acute transplantation (SR-aGv).
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In July Nature magazine had to look at the heavyweight highlights.
Time of Update: 2020-07-31
!--webeditor: "Page title"--Time is always fleeting, and in a flash July is coming to an end, and what highlights are nature magazines to study in the coming July? Small editor of the relevant article
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Nat Methods: The development of crispR-assisted new technologies to detect RNA binding proteins in living cells is expected to help research in human diseases in the future.
Time of Update: 2020-07-31
!--:page title"---- Although scientists do not yet fully understand the diversity of RNA molecules, they believe that RNA binding proteins bound to these RNA molecules are directly related to the deve
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Science: Scientists have discovered two ways in which the body ages and provides new insights into how it effectively promotes longevity.
Time of Update: 2020-07-31
27, 2020 // In a study published in the international journal Science entitled "A programmable life-goal-level-the-cell-single-cell in yeast", scientists from the University of California and other institutions have worked to solve the key mechanisms behind the body's aging mystery, in which researchers found two different pathways in the aging process and devised a new way to program these processes to extend the body's lifespan.
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Gastroenterology: Clostridium difficile causes intestinal damage and spread by inducing fibrosis!
Time of Update: 2020-07-31
", "In light of their findings, the researchers decided to investigate whether the team developed powerful antibodies that inhibit the soylysozymeliase system could be used to treat the disease." "We found an antibody that prevents the activation of the lysozyme gen, which greatly blocks the process of infection and tissue damage," said first author Milena Awad.
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New drugs for extra-use of plaque-type psoriasis! FDA approves Wynzora (calcium poisol/ dipropyl acid fentamisopine) cream!
Time of Update: 2020-07-31
, the company announced that the U.S. Food and Drug Administration (FDA) has approved The Wynzora cream (calcium pobutan and glycemic acid fentamitol, w/w, 0.005%/0.064 percent) as a daily external therapy for the treatment of plaque-type psoriasis in adults up to 18 years of age.
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Nat Commun: New technology diagnoses cancer 4 years early! Chinese and foreign scientists develop breakthrough early diagnosis technology for cancer!
Time of Update: 2020-07-31
July 24, 2020 // A team of researchers including Fudan University, Shandong University, the University of California, San Diego, Yuyuan Gene and others has developed a non-invasive blood test that can detect whether a person has five common cancers (gastric, esophagus, colorectal, lung and liver cancer) and can detect cancer four years earlier than current cancer diagnostic methods.
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How can nanoparticles help cancer research?
Time of Update: 2020-07-31
Doi: 10.1038/s41563-019-0566-2 Researchers from the University of Toronto found that it was an active, rather than passive, process that determines which nanoparticles enter solid tumors, a finding that upends previous ideas in the field of cancer nanomedicine and points the way for more effective nanotherapy, the findings of which were published recently in the journal Nature Materials.
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Slow-blocking pulmonary triple therapy! AstraZeneca Breztri Aerosphere (Budigeford) has been approved by the U.S. FDA and is listed in China!
Time of Update: 2020-07-31
data show that in patients with moderate to severe chronic obstructive pulmonary disease (COPD, COPD, COPD), with 2 duped therapy Bevespi Aerosphere (Grun brommyamin/Fumaawmodoro) and PT009 Breztri Aerosphere statistically significantly reduced the moderate to severe acute exacerbation rates by 24% (p.001) and 13% (p-0.003) (bourdnydd/Fumasinfomotro) respectively.
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PNAS: The new findings help develop the COVID19 vaccine.
Time of Update: 2020-07-31
the study provides guidance on how adjorizers can become part of a "universal" influenza vaccine, which is designed to protect people from a wide variety of flu strains.
the second injection, the antibody is more directed at the head, coming from specific natural B cells.
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New anti-inflammatory drugs! Yukbi bimekizumab medium to severe plaque type psoriasis Phase III: better than Novartis Cosentyx (good) !
Time of Update: 2020-07-31
BE-RADIANT is a randomized, multi-center, double-blind, positive-control, parallel group study designed to assess the effectiveness and safety of bimekizumab and Cosentyx in adult patients with moderate to severe chronic plaque psoriasis.
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Science Sub-journal: Inhibiting sting protein pathways can prevent some patients from developing transplant-resistant host disease.
Time of Update: 2020-07-31
July 23, 2020 // --- In a new study, researchers at the University of Miami Miller School of Medicine, the University of Minnesota and the University of Florida found that inhibiting the STING protein pathway protects some patients from graft sversus host disease, GVHD, the most serious complication of bone marrow (stem cell) transplantation.
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JAMA: TLR7 affects the risk of COVID19 in the elderly.
Time of Update: 2020-07-31
their study identified a key role in the immune response of gene TLR7 to SARS-CoV-2.
" (Bioon.com) Source: Researchers identify TLR7 gene this pre pre elders eldersssssssserly patientis patients to severe COVID-19 Original origin: Van der Made, C.
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The use of bats to control the mechanisms of viruses in the body may help develop new treatments for diseases such as COVID-19.
Time of Update: 2020-07-31
!--webeditor: "page title" -- Bats are generally thought to be infected with a number of deadly viruses, including Ebola virus, rabies, SARS-CoV-2 virus esage that causes COVID-19 Although humans expe
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Science is compiled in full! Chinese scientists have structurally revealed a powerful therapeutic antibody and SARS-CoV-2 and SARS-CoV mechanisms.
Time of Update: 2020-07-31
carrying the above amino acid residual base mutations and other reported alternative mutations of the recombinant RBD structure and H014 binding affinity is difficult to distinguish, which suggests that H014 may be currently spread inglia to the global SARS-CoV-2 strain has a wide range of neutrality.
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Cell Rep: Discover a new immune target for the flu vaccine! Broad-spectrum influenza vaccine is within reach!
Time of Update: 2020-07-31
picture source: Lead author Dr Alex Greenshields-Watson, from The University of Cardiff School of Medicine, said: "Unlike the current vaccine's main target external flu proteins, these internal proteins are highly conservative between different flu strains.
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Natno Biotechl: New technology for highly sensitive detection of COVID-19.
Time of Update: 2020-07-31
27, 2020 // --- In a recent study published in the journal Nature Biotechnology, scientists from the National Duke University School of Medicine worked closely with the National Center for Infectious Diseases (NCID), the Singapore Institute of Molecular and Cell Biology (IMCB), to develop a new test kit, "sVNT." sVNT can detect the presence of functional neutralizing antibodies (NAb) in newly coronavirus-infected people, preventing the binding of the coronavirus stingin synthasi and angiotensin-converting enzyme 2 (ACE2) host receptor.
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Gut: In-depth interpretation! Why is the body's intestinal immune response also site-specific?
Time of Update: 2020-07-31
another study found that organ-like organs produced by different fragments of the digestive tract can initiate a specific gene expression process, which depends on the homogeneity of the tissues, and that stomach and intestinal cells must produce different digestive enzymes, but the researchers were surprised to find that special binding sites in the immune system may also be part of this homogeneity.
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Interpretation! How can drug screening and CRISPR technology be combined to help create better cancer drugs?
Time of Update: 2020-07-31
!--webeditor: "page title" -- July 27, 2020 /PRNewswire/ -- A recent study published in the international journal Molecular Systems Biology entitled "Mechanism Drug-of-action discovery" In the most comprehensive analysis of how cancer drugs work at the molecular level, scientists from the Welcombe Foundation's Sanger Institute in the UK analyzed drug response data in combination with CRISPR genetic screening techniques to analyze hundreds of cancer cell lines and gain insight into how drugs target cancer cells more precisely.
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iScience: Revealthe relationship between immune cells and cancer risk!
Time of Update: 2020-07-31
July 25, 2020 /PRNewswire/ -- The immune system "monitors and blocks" the development of cancer, a view known as the Cancer Immune Alert, first proposed early in the last century. since then, epidemi