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Sci Rep: New study reveals combination therapy for COVID-19.
Time of Update: 2020-10-13
8, 2020 /---Xinface, Scientific Reports, the results of this new study support the use of fda-approved hepatitis C drug EPCLUSA (Sofosbuvir / Velpatasvir) in COVID-19 clinical trials along with other drugs.
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JAMA Dermatol: Concord Hospital's Li Chen found that Tofatib improved nail lesions and palm pustules in patients with SAPHO syndrome.
Time of Update: 2020-10-13
design, location and participants: This open-label, one-arm, forward-looking pilot study included 13 patients with SAPHO syndrome associated with nail lesions and active palm plant pustules recruited from Beijing Concord Hospital from September 2019 to December 2019.
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Dr. Li Chen: Clinical characteristics, diagnosis, imaging characteristics and treatment of SAPHO syndrome.
Time of Update: 2020-10-13
characteristics can be manifested as abnormally radioactive thick stove on the upper chest wall, the typical image is "bull head signs", if the emergence of "bullhead signs" can be diagnosed, but most patients are not typical bovine signs, clinically only about 20% of patients will appear "bullhead signs." , the type of bone scan lesions is of great value to the disease.
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AJIC: Heavy! UV rays with wavelengths of 222nm were found for the first time or could effectively kill SARS-CoV-2!
Time of Update: 2020-10-13
6, 2020 // -- In a recent study published in the international journal American Journal of Infection Control, scientists from Hiroshima University and other institutions found that using ultraviolet light (UVC, a safe range for human use) with a wavelength of 222 nm could be used to effectively kill the SARS-CoV-2 virus.
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Nat Protocol: New technology facilitates fast-moving detection of COVID-19.
Time of Update: 2020-10-13
(Photo: www.pixabay.com) The "Dipstick" technology developed by University of Queensland professors Jimmy Botella and Dr Michael Mason can extract genetic material in as little as 30 seconds and complete molecular diagnosis in 40 minutes.
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Clin Rheumatol: The clinical characteristics of SAPHO syndrome in children were first reported in China.
Time of Update: 2020-10-13
above results show that children with SAPHO syndrome have different characteristics than other groups in terms of sex ratio, frequency of jaw injury and gender distribution of skin lesions, showing more men than women.
same time, studies have also observed that bisphosphonates and TNF-α antagonists showed good therapeutic response in the treatment of SAPHO syndrome in children.
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Studies have revealed cross-species transmission of primate lysovirus.
Time of Update: 2020-10-13
"To the best of our knowledge, this is the first report to suggest that the APOBEC3 protein of great apes may potentially limit the cross-species transmission of the great ape virus and how lysovirus can overcome this species barrier." , this is the first study to shed light on molecular mechanisms.
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eLife: How immune cells control HIV infection.
Time of Update: 2020-10-13
"Our findings suggest that most HIV-specific T-cells in people receiving antiretroviral therapy can detect HIV virus with the ability to rebound after interruption of treatment," concluded Nilu Goonetilleke, a professor in the Department of Microbiology and Immunology.
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STM: New biomarkers help predict rejection after stem cell transplantation.
Time of Update: 2020-10-13
9, 2020 /---MUSC Hollings Cancer Center researcher Dr. Sophie Paczesny and others recently published a new class of immunocellular biomarkers that may reveal which patients are most at risk of transplant anti-host disease (GVHD).
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Cell Mol Life Sci: Research has found that CCL21 is an attractive new target for rheumatoid arthritis treatment.
Time of Update: 2020-10-13
study determined that CCR7 was a hallmark of RA M1 membrane fluid (SF) macrophages, and that its expression in RA monocytes and in-body differentiated macrophages was closely related to disease activity score (DAS28).
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bioRxiv: Artificial lungs help reveal the causes of blood clogs in PATIENTs with COVID19.
Time of Update: 2020-10-13
the chip can hold lung endocial cells, vascular cells and immune system cells, and allow scientists to see directly how SARS-CoV-2 attacks human cells and triggers the formation of blood clots.
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Nature: The new crown candidate vaccine BNT162b1 triggers a strong human antibody response and TH1 T cell response.
Time of Update: 2020-10-13
recently, researchers from Pfizer reported on the safety, toerability and antibody response data from an ongoing placebo-controlled, observer-blind 1/2 phase 2019 coronavirus disease (COVID-19) vaccine (known as BNT162b1) clinical trial (Nature, 2020, doi:10.1038/s41586-020-2639-4).
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Arthritis Res Ther: Serum cetoju single anti-pyrethroid 20-40mg/L is associated with a therapeutic response to inflammatory joint disease.
Time of Update: 2020-10-12
In the NOR-DMARD study, 268 patients with inflammatory joint disease (116 cases of axial spinal arthritis, 91 cases of rheumatoid arthritis and 61 cases of psoriasis arthritis) were treated for 3 months, after which serum samples were collected to determine the levels of Sertoju monoantigen and anti-drug antibodies.
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J Korean Med Sci: In Korean children between 6 and 35 months of age, immunity declined six months after the triple and four-price flu vaccinations.
Time of Update: 2020-10-12
blood clot inhibits antibody titration (a measure of serum protection rate) of recommended influenza strains 6 months after vaccination.
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Cell Biol Int: Intranscing delivery of SDF-1 alpha pre-treated stem cells improves the re-myelinization of cup multiple sclerosis.
Time of Update: 2020-10-12
SDF-1 alpha pre-treatment increases the expression of C-X-C decommoturing factor 4 (CXCR4) on the surface of BMSCs, improves cell survival and reduces in vitro apoptosis.
, the results show that intranscular delivery of SDF-1 alpha pre-treated BMSCs has some effect on improving the re-myelinization of the multi-sclerosis cup model.
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J Allergy Clin Immunol: Patients with high IL-17 asthma have psoriasis immunotypes.
Time of Update: 2020-10-12
, the results show that the high IL-17 asthma ideotope, characterized by bronchial endocrine dysfunction and an increase in antibacterial and inflammatory responses, is similar to the immunoshapype of psoriasis, including the activation of the thrombosis B2 pathline, and should be considered a biomarker of the ideology in further studies, including clinical trials of IL-17.
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Stroke: Antiphospholipid antibodies and ischemic stroke risk.
Time of Update: 2020-10-12
recently published a research paper in the leading journal in the field of cardiovascular disease, a systematic evaluation and meta-analysis designed to assess the association between aPL and RIS.
meta-analysis found that for RIS, the relative risk of aPL was 1.41 (95% CI was 0.91-2.17; I2 was 54%).
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This "dthyma cancer" will "72 change", 75-year-old grandmother, 45-year-old aunt have been recruited ...
Time of Update: 2020-10-12
After blood testing, Wang grandmother's anti-nuclear antibodies, APS-related antibodies and many other rheumatoid indicators are positive, combined with patients many years ago had a "dry syndrome", has rich clinical experience lin Jin director told Aunt Li: "Your mother is suffering from systemic lupus erythematosus." "" ah?
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Clin Oral Investig: Study reveals the role of CHI3L1 in the occurrence and progress of endexual dermatitis.
Time of Update: 2020-10-12
The AD model of mice induced by egg white protein (OVA) was studied in mice with wild type (WT) and BRP-39 invalid mutation (BRP-39-/-) to study Th2 immune response, M2 macrophage activity and skin barrier gene expression.
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J Allergy Clin Immunol: Long-term sub-tongue immunotherapy to treat peanut allergies in children.
Time of Update: 2020-10-12
after completing SLIT dosing, desensitized was assessed with up to 5,000 mg of peanut protein using a double-blind, placebo-controlled food challenge (DBPCFC).
SLIT for extended treatment provides clinically significant desensitization therapy for most children with peanut allergies, taking into account the convenience and good safety of the drug.
