JCI: Previous infection with other types of coronavirus may alleviate the condition of neo-coronary pneumonia.

March 20, 2020 /--- -- A new study suggests that a previous infection with the coronavirus that causes the "common cold" may reduce the severity of severe acute respiratory syndrome (SARS-CoV-2) infection.
study, led by researchers at Boston Medical Center and Boston University School of Medicine, also showed that previous non-SARS-CoV-2 coronavirus infections built up immunity did not protect patients from COVID-19 infections.
the findings, published in the journal Clinical Investigation, provide important insight into the immune response to SARS-CoV-2, which could have a significant impact on the development of the COVID-19 vaccine.
(Photo: www.pixabay.com) The COVID-19 pandemic killed more than 200,000 people in the United States and more than 1 million worldwide.
more and more studies are looking at specific ways in which SARS-CoV-2 virus affects different populations, including why some people are infected and have no symptoms, and why infection increases mortality.
in order to determine which type of vaccine (mRNA, viral vector) is most effective in preventing SARS-CoV-2 infection, scientists at several institutions are currently working on research and development in this area.
although SARS-CoV-2 is a relatively new pathogen, there have been many other types of coronavirus that have been endemic in humans and cause the "common cold" and pneumonia.
these coronavirus and SARS-CoV-2 share some genetic sequences, these coronavirus immune response can cross-react with SARS-CoV-2.
study, researchers looked at electronic medical records of individuals who performed respiratory board tests (CRP-PCRs) between May 18, 2015 and March 11, 2020.
CRP-PCR detects a variety of respiratory pathogens, including local "common" colds.
also examined data from individuals tested for SARS-CoV-2 between March 12, 2020 and June 12, 2020.
After adjusting for age, gender, body mass index and diabetes diagnosis, patients hospitalized with COVID-19 who had previously tested positive for CRP-PCR for coronavirus were significantly less likely to enter intensive care units (ICUs) and less likely to need mechanical breathing during COVID.
were also significantly more likely to survive in COVID-19 hospitalizations who had previously tested positive for the "common cold" coronavirus.
, a professor at Boston University Medical Center, said: "Our results suggest that people who have previously shown signs of coronavirus infection from the common cold have mild coVID-19 symptoms."
"People are often infected with coronavirus that is different from SARS-CoV-2, and these findings can help identify patients who are at lower and higher risk of complications after infection with SARS-CoV-2," said co-author Professor Joseph Mizgerd.
. (bioon.com) Source: Previousapp with other types of coronaviruses may lessen severity of COVID-19 Original source: Manish Sagar et al, Recent endemic coronaus coronaus is associated with less with severe COVID-19, Journal of Clinical (2020). DOI: 10.1172/JCI143380.