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How long can immunity last after a new coronavirus infection?
Time of Update: 2020-10-23
In order to determine whether antibodies can exist in the human body for a long time after the new coronavirus infection, the National Translational Medical Center of Ruijin Hospital, Shanghai Hematology Research Institute, National Key Laboratory of Medical Genomics, Shanghai Public Health Clinical Center and China Food and Drug Inspection Research Institute have carried out long-term monitoring of new crown infection.
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Science Sub-Journal: Reveals that IL-21 played a key role in the immune response to neurological viral infections.
Time of Update: 2020-10-23
study was recently published in the journal Science Immunology under the title "IL-21 from high-affinity CD4 T cells drives derivion of brain-resident CD8 T cells in the persistent viral." lukacher lab observed T-cells soaked in the brains of mice infected with MuPyV, pictured from Penn State.
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Nat Commun: Scientists reveal new molecular mechanisms for metastatic prostate cancer.
Time of Update: 2020-10-23
12, 2020 // -- In a recent study published in the international journal Nature Communications, scientists from the University of Tampere and others have revealed a special mechanism that may help expl
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Hypertension: Scientists hope to use artificial intelligence to screen people at high risk for cardiovascular disease.
Time of Update: 2020-10-23
Oct 12, 2020 // -- Now there is growing research evidence that bacteria living in the body's digestive tract can have far-reaching effects on the body's cardiovascular health; in a recent study publis
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New anti-inflammatory drugs! Long-term expansion of Johnson and Johnson Stelara's treatment of Crohn's disease (CD): 5 years of treatment to maintain high efficacy!
Time of Update: 2020-10-23
Key results showed that in LTE studies, more than half of patients who were randomly assigned to receive SC Stelara Q8W and continued to receive this dose in LTE studies maintained clinical response (57 percent) and clinical remission (55 percent) over a five-year period of treatment.
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New Crown Outbreak: 38.08 million! AstraZeneta Antibody Cocktail Therapy AZD7442 enters Phase 3 Clinical: Treatment and Prevention COVID-19!
Time of Update: 2020-10-23
, AstraZeneca announced that it will launch two Phase III clinical trials in the coming weeks to evaluate two combination therapies for long-acting antibodies (LAAB), the COVID-19 antibody cocktail therapy AZD7442.
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Target C3 nephropathy (C3G) the underlying cause! Novart's powerful selective factor B inhibitor iptacopan is eligible for EU priority drugs!
Time of Update: 2020-10-23
Oct 11, 2020 // -- Novartis recently announced that the European Medicines Agency (EMA) has granted iptacopan (LNP023) priority drug eligibility (PRIME) for the treatment of C3 nephropathy (C3G).
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Regeneron neutralizing antibody combination therapy becomes the first FDA approved Ebola therapy
Time of Update: 2020-10-22
Today, the FDA announced the approval of Regeneron's development of a medium-antibody cocktail therapy Inmazeb (atoltivimab, maftivimab and odesivimab-ebgn, formerly called REGN-EB3) for the treatment of Ebola virus infection in adults and children.
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elife: Research reveals pathogenic mechanisms of malaria parasites.
Time of Update: 2020-10-22
.com Source: Scientists shed new light on mechanisms of malaria parasite motility Original source: Dihia Moussaoui et al, Full-length Plasmmodium falciparum myosin A and essential light light chain PfELC structures provide new anti-malarial targets, eLife (2020).
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Sci Rep: Study reveals the underlying mechanisms of joint damage.
Time of Update: 2020-10-22
now, a new interdisciplinary study suggests that the accumulation of proteins used to lubricate joints may actually be a precursor to joint disease.
Reesink's study found an increase in lubricin in the joints in canines with torn knee ligaments, contrary to traditional medical assumptions.
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Nat Microbiol: New discoveries by Chinese scientists! Antimicrobials or promising treatments for SARS-CoV-2 infections!
Time of Update: 2020-10-22
used Syrian hamsters as a target, the researchers found that one of the drugs, called RBC, ranitidine bismuth citrate, could be used as a potential anti-SARS-CoV-2 infection agent.
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Analy Chem: Scientists have developed new tools to study the function of the human body's immune system.
Time of Update: 2020-10-22
15, 2020 // -- In a recent study published in the international journal Analytic Chemistry, scientists from the University of Alberta and other institutions developed a new tool to help study the function of the human body's immune system, and the results may help improve understanding of the pathogenesis of cancer and neurodegenerative diseases such as Alzheimer's disease.
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PNAS: Pig coronavirus can replicate in human cells.
Time of Update: 2020-10-22
Edwards, the study's first author, tested several types of cells by infecting cells with a synthetic strain of SADS-CoV to understand how high the risk of cross-species contamination is.
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Gastroenterology: Scientists hope to develop a new precision medicine treatment for pancreatic cancer.
Time of Update: 2020-10-22
study, researchers developed new molecular markers to predict which patients would react to drugs that target DNA damage by using cell lineages and organs from the body of pancreatic cancer patients.
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Cell Rep: Glucotoxin promotes tissue regeneration.
Time of Update: 2020-10-22
study found that a toxic mixture of Staphylococcus acobacteria that destroys cells and tissues also has a positive effect: bacterial toxins stimulate specific immune cells to produce specialized messengers that help reduce inflammation and promote tissue healing.
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Nutrients: Ingesting complete fruits such as kiwis may effectively enhance the body's vitality, which is inextricable to vitamin C!
Time of Update: 2020-10-22
the study, researchers conducted a placebo-controlled intervention trial to test whether increasing vitamin C intake through whole fruits or pills improved the body's vitality and enthusiasm for life.
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NSAIDs are potentially drugs that inhibit the progression of radiology in central spina bna bna bnabitis.
Time of Update: 2020-10-21
article reviews clinical studies related to NSAIDs and biological agents delaying the progression of SpA radiology, as well as genetic, animal, and clinical evidence of nsaIDs' effects on bone formation, and looks ahead to future research.
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NEJM: RNA identification of PRIME cells can be used to predict rheumatoid arthritis flares.
Time of Update: 2020-10-21
the study, published in the New England Journal of Medicine, was entitled "RNA Finding of PRIME Cells Predicting Rheumatoid Arthritis Flares." rheumatoid arthritis is an immune system disease that causes inflammation of joints, especially around the hands and feet.
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Ann Rheum Dis: Advanced interstitiotic pulmonary disease in patients with systemic sclerosis.
Time of Update: 2020-10-21
study used data from the European Steyring and Research (EUSTAR) database to determine the overall course, progression patterns and risk factors for progressive interstitiac pulmonary disease (ILD) in SSc-ILD patients.
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Targeting a new nanoantibody for ADAMTS5 osteoarthritis, Merck awarded it to Novartis for 50 million euros.
Time of Update: 2020-10-21
Merck KGaA has signed a licensing agreement with Novartis to develop clinical studies of osteoarthritis drugs.
: Under the terms of the deal, Merck will license the M6495 to Novartis for further evaluation of osteoarthritis patients.
