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eneuro: New discovery! Diabetes drugs may slow the progression of Parkinson's disease!
Time of Update: 2020-12-19
in this study, entitled "Alpha-synuclein aggregates increased conductance of substantia nigra dopamine neurons, an effect partly reversed by the KATP channel resedor glibenclamide", the researchers found that by introducing a low-concentration structure-determined α synaptic nucleoprotein aggregate into a single dopamine neuron, the cell membrane's channels are turned on, greatly reducing the neurotic excitability of the cell membrane.
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bioRxiv: By editing key genes in human nerve cells, it is expected to alter their risk of Alzheimer's disease
Time of Update: 2020-12-19
People who express the gene mutation are four times less likely to develop Alzheimer's disease, and in the study, researchers edited human brain cells to make individuals carry the gene mutation A673T, which they found may reduce an individual's risk of developing Alzheimer's disease.
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J Neurosci: Why does stress cause infertility in humans? RFRP neurons in the brain may be the key!
Time of Update: 2020-12-19
December 7, 2020 // -- In a recent study published in the international journal The Journal of Neuroscience, scientists from the University of Otago and others found a missing link between stress and infertility, and by conducting research in the lab, they confirmed that a group of nerve cells called RFRP neurons at the bottom of the brain may activate under stress conditions in the body and then inhibit the function of the reproductive system.
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Sci Rep: Reveals the key role that gut bacteria play in the body's normal sleep
Time of Update: 2020-12-19
In the study, researchers gave a group of mice up to four weeks to ingest a mixture of antibiotics that removed their gut microbes, and then compared the differences between the mice and the control mice who ate the same diet, the digestive process that breaks down food into small pieces of metabolites.
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Science: New high-resolution implants make it possible to restore vision through electrical stimulation of the brain
Time of Update: 2020-12-19
new study, researchers from research institutions such as the Netherlands Institute of Neuroscience found that newly developed high-resolution implants make it possible for the visual cortical layer to recognize artificially induced shapes and perceived objects.
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4, 2020 in the journal Science
Time of Update: 2020-12-18
6.Science: 200 scientists around the world have teamed up to reveal the common weaknesses of SARS-CoV-2, SARS-CoV-1 and MERS-CoV coronavirus doi:10.1126/science.abe9403, a study published in the international journal Science Scientists from Georgia State University and others have found common weaknesses in three deadly coronavirus: SARS-CoV-2, SARS-CoV-1 and MERS-CoV, such as frequently hijacking signaling path paths in cells, which may hopefully help researchers find potential targets and treatments to effectively and widely suppress coronavirus infections.
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Sci Adv: New study could help treat Alzheimer's disease
Time of Update: 2020-12-18
before identifying the specific pathological characteristics of the disease, researchers at Case Western Reserve University have identified new ways to target potential treatments aimed at reducing the degradation of whiteness that impairs the normal functioning of brain circuits.
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Lancet Neurology: Application of methiciltic acid in patients with cerebral hemorrhage (STOP-AUST): A multi-center, randomized, placebo-controlled Phase 2 trial
Time of Update: 2020-12-18
Globally, 18 million people suffer from the after-effects of cerebral hemorrhage, and 3 million people die each year from the disease, accounting for 5 per cent of all human deaths. the clinical prog
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PLoS Biol: Use video games to reveal the origins of emotions
Time of Update: 2020-12-18
results, published in the journal PLOS Biology, show that different emotional components distribute multiple neural networks in parallel throughout the brain, and that their instantaneous synchronization produces emotional states.
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Cell Stem Cell: Accident! Free fundamentals are good for the brain and can promote the production of new nerve cells by neural stem cells
Time of Update: 2020-12-18
, "These stem cells are an important basis for neuroplasticity, which we call the brain's adaptability," said Professor Kempermann.
team was able to confirm in mice that neural stem cells contained large amounts of free fundamentals compared to adult nerve cells.
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Lancet Neurology: The biological and clinical characteristics of gene carriers are far from the rate expected in the Huntington's Disease Youth Study (HD-YAS): a cross-sectional analysis
Time of Update: 2020-12-18
Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysis.
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Pathogens: A new study shows the first case in which new coronary pneumonia triggers a recurrence of Green-Barre syndrome
Time of Update: 2020-12-18
a new study, researchers from the Robert Wood Johnson School of Medicine in Rutgers reported the first case of COVID-19 triggering a recurrence of Greene-Barre syndrome.
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AES 2020: Real-world evidence of the anti-epileptic drug FYCOMPA
Time of Update: 2020-12-18
epilepsy is that a patient continues to have repeated seizures without induced causes.
the rate of seizures in patients with systemic epilepsy (SGS) in an ex post-mortem analysis of phase III FREEDOM studies.
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Stroke: Relationship between the severity of non-alcoholic fatty liver disease and the risk of ischemic stroke
Time of Update: 2020-12-17
In a recent study published in TheStroke, an authoritative journal in the field of cardiovascular disease, researchers aim to proactively assess whether non-alcoholic fatty liver disease (NAFLD) and its severity can predict the occurrence of community-based ischemic stroke (IS).
excluding alcoholism and other liver diseases, the researchers recruited participants with no history of stroke, cancer, or myocardial infarction.
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JCEM: Effect of thyroid state on local brain capacity
Time of Update: 2020-12-17
In a study published in Metabolism, researchers used the International Classification code 10, the multigene thyroid score (pT value) of different thresholds associated with thyroid traits in the British biolibrary, and image-derived esoteric (n-18825) to investigate the effects of thyroid disease diagnosis and genetic risk of thyroid status on the volume of gray matter in the small brain and subder cortical layer.
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J Pineal Res: Luo Chengliang/俤/Tao Luyang team has made important breakthroughs in the field of brain trauma and iron death
Time of Update: 2020-12-17
above results show that under physiological conditions, Fth-KO mouse cortical iron metabolism is broken, which in turn shows that the iron storage function of neuron ferrite played an important role in maintaining iron stability in the brain.
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Lancet Neurology: Clinical Characteristics and Prognostics of Patients with Traumatic Brain Injury in China: A Forward-Looking, Multi-Centered, Longitudinal Observational Study
Time of Update: 2020-12-17
study, we analyzed the epidemiological characteristics, treatment and prognostics of TBI patients hospitalized in China.
Clinical characteristics and outcomes in patients with traumatic brain injury in China: a prospective, multicentre, longitudinal, observational study.
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Arch Phys Med Rehabil: Strength or oxygen training can effectively improve the daily activity of people with Alzheimer's disease
Time of Update: 2020-12-17
results showed significant improvements in Bartel index, mini-psychiatric examination, Montreal cognitive assessment, and plasma monocytical chemically active protein-1 levels in patients in the strength training group after completing the project.
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Nat Commun: An observational genomic meta-analysis of PTSD in 10 military and civilian queues
Time of Update: 2020-12-17
the study included 10 military and civilian queues, including data on DNA methylation from 1,896 PTSD cases and trauma exposure controls.
after multiple comparison adjustments, the four CpG site points in the aromatic hydrocarbon inhibitor (AHRR) were associated with PTSD, and the degree of DNA methylation in PTSD cases was lower than that of the control group.
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JAMA Neurol: Ezogabine's effect on the excitability of motor neurons in the cortical and spinal cords of ALS patients
Time of Update: 2020-12-17
Through transcranial magnetic stimulation and threshold tracking of nerve conduction studies, the excitability of motor neurons in the cortical and spinal cords in ALS patients was demonstrated to be high, although the excitability indicator has not yet been used as a biomarker for pharmacoetics in clinical trials.
