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How is dizziness/vertigo treated?
Time of Update: 2021-04-14
"Medical Neurology Channel" has planned a series of dizziness/vertigo mind maps, and previously released the most comprehensive mind map of "Dizziness/Dizziness Diagnosis", hurry up and collect!
This article Source: medical profession Neurology Channel author: Xin flower flat paper drawing: River Sub Editor: Mr.
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Molecular Psychiatry | Wu Qi's team reports a novel neural circuit regulation mechanism and targeted combination therapy for the co-occurrence of obesity and anxiety and depression
Time of Update: 2021-04-14
After correcting the functional defects caused by the high-fat diet in the loop through a series of genetic or pharmacological methods, the group of researchers first found that the anxiety and depression symptoms completely disappeared, and then surprisingly found that the animal's food intake was strongly suppressed , And eventually lead to obesity symptoms are almost completely eliminated.
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"Sleep and sleep" sleep disorder, a table tells you how to treat it
Time of Update: 2021-04-14
Narcolepsy is a type of sleep disorder, manifested as pathological sleep (also called excessive daytime sleepiness) or a group of clinical syndromes accompanied by cataplexy, sleep hallucinations, and sleep paralysis.
In 60% of narcolepsy patients, decomposing paralysis occurs within three to five years after the onset of sleepiness [7].
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How much do you know about the related factors of cerebral microhemorrhage in patients with dominant hereditary Alzheimer's disease?
Time of Update: 2021-04-14
Therefore, in order to study the inherent clinical risks associated with CMHs and determine the characteristics of high-risk individuals with ARIA-H abnormalities, American scholar Nelly Joseph-Mathurin analyzed 511 families from 19 DIAN locations with dominant inherited AD (DIAD).
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Nature: Xu Yajie's team reveals the mechanism of stress-induced hair loss and proposes a method to reverse hair loss
Time of Update: 2021-04-14
All in all, this study shows that cortisol, the stress hormone caused by stress, can control the resting period of hair follicle stem cells by inhibiting GAS6, thereby revealing the specific mechanism of "stress causing hair loss".
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PNAS: Tsinghua University's Yao Jun team discovered that miRNAs regulate brain hippocampal cognitive function and its mechanism
Time of Update: 2021-04-14
On March 29, 2021, the Yao Jun Laboratory of the School of Life Sciences, Tsinghua University, published a titled miR-218-2 regulates cognitive functions in the hippocampus through complement component 3–dependent modulation of synaptic in the Proceedings of the National Academy of Sciences (PNAS) Research paper on vesicle release.
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Hao Junwei's team from Xuanwu Hospital discovers a new mechanism of neuroinflammation regulation after stroke丨Expert perspective
Time of Update: 2021-04-14
Introduction On March 26, 2021, the team of Professor Junwei Hao from the Department of Neurology, Xuanwu Hospital of Capital Medical University published a research paper entitled "Microglial PGC-1α protects against ischemicbrain injury by suppressing neuroinflammation" in Genome Medicine (IF: 10.
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Neurology: Mental and cognitive symptoms are common among Huntington's disease gene carriers
Time of Update: 2021-04-14
0000000000011893" target="_blank" rel="noopener">Impact of Psychiatric and the Timing, Cognitive, and Motor Abnormalities in Huntington Disease neurology.
0000000000011893" target="_blank" rel="noopener">Impact of Psychiatric and the Timing, Cognitive, and Motor Abnormalities in Huntington Disease neurology.
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IEEE J Biomed Health Inform: To detect early mild cognitive impairment, the genetic evolutionary random forest method is promising
Time of Update: 2021-04-14
Xia-an Bi proposed a genetic evolutionary random forest (GERF) algorithm based on genetic data and resting functional magnetic resonance imaging (rs-fMRI) data to discover early mild cognitive impairment (EMCI) dangerous genes and Disease-related brain areas.
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Neurology: Chinese original research-Parkinson's motor phenotype is closely related to cortical folds
Time of Update: 2021-04-14
0000000000011894" target="_blank" rel="noopener">Association of Gyrification Pattern, White Matter Changes, and Phenotypic Profile in Patients With Parkinson DiseaseXie Tang, Yuanchao Zhang, Daihong Liu, Yixin Hu, Lingli Jiang, Jiuquan Zhang neurology.
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JAMA Sub-Journal: Cost-effectiveness of opioid addiction treatment
Time of Update: 2021-04-14
When criminal justice costs are included, all forms of MAT (including buprenorphine, methadone, and naltrexone) save costs compared to no treatment, saving $25,000 to $105,000 in lifetime costs per person.
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Cell Sub-Journal: Long-term social inactivity makes males more violent and females further away from society. This neural circuit is actually "behind the scenes."
Time of Update: 2021-04-14
This indicates that the weakening of the firing activity of pyramidal neurons in the PFC brain area is closely related to the aggressive behavior of male mice and the social disorder of female mice.
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Nature Sub-Journal: Self-developed and mature human cerebral cortical organs
Time of Update: 2021-04-14
Location of neurodegenerative disease genes Note on hCS differentiation: AD: Alzheimer’s disease PD: Parkinson’s syndrome 360 Comment: Scientists at the University of California and Stanford University have innovatively developed cortical organs that can mature themselves and can simulate the body in vitro using an in vitro model The process of neurodevelopment provides a simulation research tool for studying neurodevelopmental insufficiency, psychiatric disorders, neurodegenerative diseases, etc.
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Express | Treatment of Alzheimer's disease, telomerase modulator positive phase 2 clinical results released
Time of Update: 2021-04-14
In a randomized double-blind, placebo-controlled phase 2 clinical trial, a total of 96 Alzheimer's disease patients received placebo or different doses of GV1001 treatment.
Reference: [1] GemVax's highly promising Phase II Alzheimer's disease clinical trial results targeting telomerase published in prestigious Alzheimer's Research & Therapy' journal.
Retrieved March 30, 2021, from -highly-promising-phase-ii-alzheimers-disease-clinical-trial-results-targeting-telomerase-published-in-prestigious-alzheimers-research--therapy-journal-301258354.
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Can you correctly diagnose this patient with shortness of breath and difficulty walking?
Time of Update: 2021-04-14
Before further examination of the second patient, 47 days after the onset of symptoms in this patient, the mother of this patient was hospitalized with acute respiratory failure; her canned green bean botulinum toxin tested positive.
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China's latest consensus on diagnosis and treatment of early-onset Parkinson's disease is released. How much do you know?
Time of Update: 2021-04-14
In view of the early age of onset of EOPD, long course of disease, large heterogeneity of clinical manifestations, relatively atypical symptoms, easy to be overlooked and misdiagnosed, domestic experts in the field have formed a consensus on the diagnosis and treatment of early-onset Parkinson's disease for reference .
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Not to be underestimated, Professor Zhu Lingqiang from Huazhong University of Science and Technology reveals microRNA-mediated memory impairment in Alzheimer’s disease
Time of Update: 2021-04-14
By injecting miR-135a-5p mimics or LV virus that silences Rock2 expression into the hippocampus of 9-month-old AD model mice, the dendritic spine density of neurons returned to normal levels, and the synaptic transmission function also returned to normal.
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Pay attention to the mental and behavioral symptoms of children with epilepsy, and rational drug selection is the key
Time of Update: 2021-04-14
The third-generation anti-epileptic drug, lacosamide, can effectively control epileptic seizures and significantly improve children's bad behavior.
Figure 1: Lacosamide can effectively improve the Connor's Behavior Rating Scale score in children with epilepsy.
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Three major research advances in stroke neuroprotection, worth knowing
Time of Update: 2021-04-14
Results of the stratified analysis of ESCAPE-NA1 study NA-1 is the first drug that has been proven to have neuroprotective effects after AIS.
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Today's "Science": Distressed!
Time of Update: 2021-04-14
Dylan Reid (right) (Credit: Salk Institute, Dylan Reid) Taken together, since cell division cannot repair DNA damage, nerve cells can only rely on their own limited ability , To give priority to repairing those genomic regions that are vital to our function, so that we can avoid various neurological diseases.
