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Low doses of amycin may overcome leukemia resistance
Time of Update: 2020-12-30
a new study published online April 20 in Nature Cell Biology, Researchers in China and the United States report on a new approach that could overcome leukemia resistance: the use of low-dose, chemotherapy drug ammoxin, widely used to treat multiple cancers.
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The most "true" slow plus acute liver failure mouse model was successfully constructed
Time of Update: 2020-12-30
The team of Professors Xiang Xiaogang and Xie Qing of Ruijin Hospital, affiliated with Shanghai Jiaoxuan University School of Medicine, worked with Professor Gao Bin of the National Institute of Alco
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Eya2 has been expressed in human prostate cancer and regulates polyene yew alcohol sensitivity and mitochondrial membrane protons through akT/Bcl-2 signaling paths
Time of Update: 2020-12-29
In addition, data from the Oncomine database showed elevated levels of EYA2 mRNA expression in prostate cancer tissue compared to normal tissues.
Therefore, data from the TCGA prostate queue show that EYA2 mRNA is positively related to the expression of Bcl-2 and MMP7.
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Research reveals the co-evolution of human and immune diseases
Time of Update: 2020-12-29
Lead author Jorge Dominguez-Andres, a researcher at the Netherlands Institute of Molecular Life Sciences, and others collected data from genetic, immunology, microbiology and virology studies and determined how the DNA of people in different communities who are usually infected with bacterial or viral diseases changes, leading to inflammation.
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FightING AIDS, bringing about change in the community Springer Nature is with you
Time of Update: 2020-12-29
The article published in this journal focuses on addressing basic public health issues related to impoverished infectious diseases, including all aspects of pathogen and parasite vector biology, such as diagnosis, testing, treatment, case management, epidemiology and modeling.
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Progress has been made in the study of swine fever and natural immunity
Time of Update: 2020-12-29
Chen Jinding's preliminary research confirmed that autophagy, as an inherent protective mechanism of cells, not only can not effectively remove the swine fever virus in the cells, but is held hostage by swine fever virus to promote the replication and release of sub-viruses, swine fever virus-induced autophagy inhibits apoptosis by lowering the RLR signal.
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Green tea combined with exercise can help relieve fatty liver
Time of Update: 2020-12-29
study also found that green tea extract combined with exercise increased gene expression associated with new mitochondrial formation in mice, which helped to explore specific mechanisms for the combination of green tea extract and exercise to relieve fatty liver.
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Columbia University and MIT have jointly discovered new pathological mechanisms for diseases of the hemagtic system
Time of Update: 2020-12-29
February 26, 2020, the Chasan team at Columbia University and the Eliezer Calo team at the Massachusetts Institute of Technology published a research paper online in Nature entitled DNA-PKcs has KU-function in the rRNA processing and haematopoiesis, revealing the new function of DNA repair protein DNA-PK in RNA processing and hematopoilation.
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Scientists have found new drug targets for antiviral infections in the body
Time of Update: 2020-12-29
The Center for Excellence and Innovation in Molecular Cell Science of the Chinese Academy of Sciences (Institute of Biochemistry and Cell Biology) Wang Hongyan Research Group, in cooperation with Wei
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Scientists have discovered a new model of phospholipids regulating the fate of pot stem cells
Time of Update: 2020-12-29
according to , the study found that phospholipids play a dynamic remodeling function in the process of reprogramming somatic cells to induce popotential stem cells (iPSCs), and identified phosphatidylethanolamine as a key lipid molecule in multipotential access and maintenance, which is the key event of reprogramming through signal transduction regulation "interstitial-supersethic conversion (MET).
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A pharmaceutical factory smaller than a boxing ring was born
Time of Update: 2020-12-29
a small, fully automated assembly line can produce 4,800 pills an hour to meet a broader supply of drugs, according to a study published in Chemical Communications.
To save the space, time and resources needed to produce the drug, the researchers built a complete pharmaceutical plant of just 30.7 square meters.
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World AIDS Day 2019: Working together to fight AIDS A selection of BMC studies
Time of Update: 2020-12-29
The AGEP study recruited Zambian girls aged 10-19 and divided them into four groups, three of which participated in a two-year "safe space" conference hosted by older women in the community, focusing on health, life and financial skills.
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Inhalation of particles produced by fuel may cause brain tumors
Time of Update: 2020-12-29
They found that an increase in air pollution of 10,000 nanoparticles per cubic centimeter could lead to one more brain cancer case per 100,000 people.
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Progress has been made in the treatment of neuroblastoma
Time of Update: 2020-12-29
researchers at the University of Seville and the Institute of Biomedical Research in Seville, Spain, recently determined that a protein called CD44 can identify cancer stem cell populations that cause neuroblastoma invasiveness and low survival.
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The near-atomic resolution structure of human herpes virus has been analyzed
Time of Update: 2020-12-29
HHV-6 virus infection causes widespread harm, but there is currently no high-resolution structure of the virus, as well as structure-based drugs or vaccine antiviral programs.
Due to its high bonding with host cells, HHV-6B is difficult to achieve in-body proliferation culture, which has become a major problem in the analysis of atomic resolution structure.
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The study confirmed the new target of analgesy
Time of Update: 2020-12-29
in the field of pain treatment, traditional opioids have better analgesic effect, but because of their addictive drug abuse has produced serious problems, resulting in huge economic losses, medical b
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Sea ice melts or accelerates the spread of disease
Time of Update: 2020-12-29
reduction in Arctic sea ice caused by climate change could allow pathogens that infect marine mammals to spread more frequently between the North Atlantic and the North Pacific, according to a recent study published in Scientific Reports.
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Different foods are associated with different types of stroke
Time of Update: 2020-12-29
food is associated with different types of stroke risk, according to a study published February 23 in the European Heart Journal.
But eating an additional 20 grams of eggs a day increases the risk of hemorrhagic stroke by 25 percent, equivalent to two out of every 3,000 people over a 10-year period.
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The study found new genes associated with alcohol dependence
Time of Update: 2020-12-29
to this end, the researchers tested methylation levels in human brain tissue samples and conducted an observational genetic group association study (EWAS) to screen the differential methylation region (DMR) associated with alcohol dependence, where DMR-DLGAP2 is located upstream of the DLGAP2 gene.
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The study found a new target for the prevention and treatment of diabetic perennia neuropathy
Time of Update: 2020-12-29
These studies show that the absence of the Sarm1 gene can alleviate diabetic exostial neuropathy in mice, and suggest that mitigating axon degenerative lesions, such as targeting Sarm1, may be an effective strategy to prevent and treat diabetic exostial neuropathy.
