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CMI(IF=22) The team of Xiaoyong Man of Zhejiang University revealed that the epidermal immune microenvironment plays an important role in the development of psoriasis
Time of Update: 2023-01-06
Original link: style="margin-right: auto;margin-left: auto;outline: 0px;width: 30px;display: inline-block;">—END—The content is [iNature]The skin acts as the first battleground for the host, as well as a physical and immune barrier, involved in defending against exogenous pathogens and physical dangers, and maintaining tissue homeostasis.
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What does the ACR/EULAR RA mitigation standard update optimize? Research Express
Time of Update: 2023-01-06
0 is more consistent with SDAI or CDAI mitigation standards Among the 2048 trial participants included in the study (1101 with early RA and 947 with confirmed RA), after six months of treatment, the response rate using Boolean 2.
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The Immunity TCR-Engine can be used to design synthetic TCRs with enhanced potency and specificity
Time of Update: 2023-01-06
Written by | T cells genetically modified to express TCR that recognize tumor-associated antigens are helpful for cancer immunotherapy, but usually because of the risk of cross-reactivity with off-tar
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Ding dong! Check the 2022 ACR Today Hot Express to unlock the latest data of the Hopkins Lupus Queue
Time of Update: 2023-01-06
Chinese Journal of Internal Medicine,2020(03):172-173-174-175-176-177-178-179-180-181-182-183-184-185 [6]RealWorld Effectiveness of Belimumab in Patients with SLE in the United States[7] Unfavorable Outcomes Associated with Current Standard of Care in the Management of Patients with Systemic Lupus Erythematosus[8] Association Between Cumulated Hydroxychloroquine in Systemic Lupus Erythematosus and Development of Cardiac Conduction Alterations: A Multiple Logistic Regression Analysis[9] World Health Organization.
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Obstetricians tell you that pregnant women with rheumatism do this for testing and management
Time of Update: 2023-01-06
Conclusion: Through the use of a variety of clinical examinations and monitoring and treatment methods, rheumatism is no longer a contraindication to pregnancy and childbirth in such pregnant women.
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The latest paper of the 2022 Nobel Prize winner: targeting sugar molecules on the surface of cancer cells to enhance the effect of immunotherapy
Time of Update: 2023-01-06
Link to the paper: style="color: rgb(136, 136, 136);font-size: 12px;" _mstmutation="1" _istranslated="1"> open reprint Welcome to Moments and WeChat groups SourceChina Biotechnology NetworkAs we all know, the immune system is the body's defense network, with various abilities to remove abnormal cells.
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Focus on the cutting-edge progress in the field of lupus, ACR2022 first day conference wonderful research report!
Time of Update: 2023-01-06
In a retrospective study of 442 patients [1], belilumab combination therapy for 12 months significantly reduced SLEDAS disease activity scores in SLE patients compared with usual care (SoC) (Figure 1), and more patients achieved treatment goals of low disease activity (LDA) or remission (Figure 2), suggesting that belimumab helps patients with SLE achieve LDA (HR).
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How is xerostomia diagnosed, treated and prevented? 2022 ACR Essence Express There are benefits at the end of the article
Time of Update: 2023-01-06
Figure 1: Dry oral mucosa/erythema care for patients with dry mouth should focus on the complications of xerostomia, particularly those with severe saliva flow deficit.
Figure 1: Dry oral mucosa/erythema care for patients with dry mouth should focus on the complications of xerostomia, particularly those with severe saliva flow deficit.
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Express Potential "first-in-class" therapy! More than $100 million to help bifunctional antibodies enter Phase 3 clinical trials
Time of Update: 2023-01-06
The funds raised will be used primarily to advance its lead project, obexelimab, a bifunctional antibody into a global Phase 3 clinical trial to review the efficacy and safety of this drug in the treatment of immunoglobulin G4-related disease (IgG4-RD).
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Guangdong University of Technology ES&T: Chloropolycyclic aromatic hydrocarbons induce THP-1 macrophage immunosuppression—characterized by disorders of amino acid metabolism
Time of Update: 2023-01-06
Chlorinated PAHs induce immunosuppression in THP-1 macrophages characterized by disrupted amino acid metabolismFirst author: Li XinyanCorresponding author: Luan TiangangAuthor: Guangdong University of TechnologyBy Xinyan Li, Mei Ma, Bilin Zhao, Na Li, Ling Fang, Donghong Wang, Tiangang Luan*Research highlightsIn this study, high-throughput multi-target immunotoxicity detection and non-targeted metabolomics technology were integrated to jointly evaluate the immunotoxicity of chlorinated polycyclic aromatic hydrocarbons and explore the immune metabolism mechanism.
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2022 ACR essence content highlights, see is earn!
Time of Update: 2023-01-06
*For medical professionals onlyJoin hands with big coffee, learn rheumatism academic feast together!The 2022 American College of Rheumatology Annual Meeting (ACR) was held on November 10~14, Eastern T
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When is lupus started with immunosuppressants? How to choose 7 drugs?
Time of Update: 2023-01-06
Download the decision assistant App, the guide is free at any time ~ References: [1]2020 Chinese Systemic Lupus Erythematosus Diagnosis and Treatment Guide ▼▼▼Click to read the original article to download the AppImmunosuppressants are recommended in patients with systemic lupus erythematosus (SLE) who do not respond well to hormonal plus hydroxychloroquine, or who are unable to adjust the dose of the hormone below a relatively safe dose.
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What should I do if there is organ involvement in lupus? The guide summarizes these 6 tips
Time of Update: 2023-01-05
Download the Decision Assistant App, the guide is free at any time ~▼▼▼Click to read the original article to download the AppFor medical professionals onlyOpen the "Clinical Decision App" and talk to authoritative guides at home and abroad!
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Wen "bone" knowledge, let's talk about the "new news" of osteoarthritis, an "old acquaintance"
Time of Update: 2023-01-05
"In October 2022, the latest "Osteoarthritis Diagnosis and Treatment Specification" [2] issued by the Rheumatology Branch of the Chinese Medical Association advocates that OA is divided into five subtypes: load-based, structure-based, inflammation-based, metabolism-based and system-factor-based [3]。 Professor Xu Jian believes that the proposal of this classification method shows that our understanding of OA has changed significantly and improved, which can help us better distinguish between OA and RA.
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How do RA patients eat and exercise? The first ACR guide tells you!
Time of Update: 2023-01-05
Come to the "doctor's station" and take a look 👇*For medical professionals onlyACR's first guide to integrated management interventions for RA!The annual American College of Rheumatology (ACR) is one of the world's largest and most influential international conferences, bringing together world-class basic science and clinical researchers, clinicians, and nursing research groups.
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Pulmonary hypertension in connective tissue disease: epidemiology, pathogenesis, and treatment
Time of Update: 2023-01-05
Epidemiology of pulmonary hypertension in connective tissue diseaseREVEAL is a multicenter (55-center) observational PH registry study designed to characterize the patient population with PH in the US.
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The combination of traditional Chinese medicine and western medicine in the prevention of rheumatoid arthritis
Time of Update: 2023-01-04
J Intern Med. Traditional medicine remains an important part of healthcare around the world.
J Intern Med. Traditional medicine remains an important part of healthcare around the world.
J Intern Med. Traditional medicine remains an important part of healthcare around the world.
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These 4 golden nursing rules, lupus nephritis patients have to know!
Time of Update: 2023-01-04
Kepujun summarized the red and black list of the diet of lupus nephritis patients for everyone [11], come and see if you eat right?Red list appropriate intake of high proteinPatients with systemic lupus erythematosus with kidney damage often lose a large amount of protein from the urine, which can cause hypoproteinemia, so adequate high-quality protein supplementation is essential.
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Five major abnormal mechanisms of T cells in systemic lupus erythematosus
Time of Update: 2023-01-04
T cell phenotypic changes CD4+ T cells regulate the immune response by providing co-stimulatory signals and cytokines, and are key drivers of SLE autoantibody response, and the cytolytic activity of CD8+ T cells can cause functional impairment in SLE patients.
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26 common autoimmune diseases
Time of Update: 2023-01-04
To date, more than 80 autoimmune diseases have been identified, ranging from systemic (such as systemic lupus erythematosus, which can affect the skin, joints, kidneys, and central nervous system, etc.
