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Science Advances: What robs older people of their immunity?
Time of Update: 2020-08-24
, the researchers finally determined that the CD4 and FoxP3-T cells that produced IL-10 in older mice were primarily Tfh cells.
researchers found that antigen-specific Tfh10 cells, the main population of T-cells that produce IL-10, appeared after vaccination in older mice.
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Novarhua IL-17A monoantire resistant to Cosentyx: EU-approved first-line treatment for children with psoriasis.
Time of Update: 2020-08-23
: The approval is based on two phase 3 studies of children and adolescents aged 6-18.
, 59.5 per cent of children received completely transparent skin (PASI 100) at week 12 and 67 per cent at week 24.
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Cancer Res: HDAC6 inhibitors may be able to effectively control the growth and cancer metastasis of triple-negative breast cancer.
Time of Update: 2020-08-20
the first time in the study, researchers found that HDAC6 inhibitors not only improve patients' responses to immunotherapy, but also reduce breast cancer and have minimal toxic effects; Original origins from : Debarati Banik, Satish Nopalonele, Melissa Hadley, et al, HDAC6 Plays a Noncanonical Role in The Regulation of Antitumor Immune Responses, Fellon, and SOrs OfoCancer, Cancer Research (2020).
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Cancer Res: Reveals the molecular mechanisms by which ovarian cancer grows and evolves in the body.
Time of Update: 2020-08-20
the study entitled "Multi-omic analysis of the subtype evolution and heterogeneity in high-grade serous ovarian carcinoma" has some basic scientific significance, in which the researchers present their own decades-long insightinto into the process of tumor development and the practical implications of these ideas for the development of cancer subtype targeted therapies.
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Cell Metabol: Acetate or the ability to regulate the function of immune cells to effectively eliminate pathogen infection.
Time of Update: 2020-08-20
Photo Source: CC0 Public Domain Immune Cells Protect the Body and Effectively Eliminate Pathogens when InfectionS Occur, while the Soldiers (Immune Cells) that Make Up This Team Perform Better only in enemy attacks, and the mixing of molecules and metabolites at the infected site plays a decisive role in how immune cells function.
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Nat Commun: Scientists are hoping to develop new treatments for malaria.
Time of Update: 2020-08-20
image source: Australian National University malaria is caused by the malaria parasite, mainly through the bite of infected mosquitoes to humans, the researchers say, the malaria parasite is evolving to develop some resistance to current drugs, which may be a major threat to effective control and elimination of malaria, in the article, the researchers focused on a protein called PfCRT, which is critical to the generation of malaria parasite strains, but also a potential new drug target.
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J Allergy Kleinol: Skin flora regulates skin and lung allergic inflammation.
Time of Update: 2020-08-11
To further assess the importance of microbiome in the development of the skin immune environment, the authors conducted transcriptional analysis of immature skin from adult SPF and GF mice.
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Two NEJM papers show that the experimental new crown vaccine mRNA-1273 has broad prospects.
Time of Update: 2020-08-06
!--:page:--2 ---9 (UPI) -- In a new study, researchers from the National Institutes of Allergy and Infectious Diseases (NIAID) affiliated with the National Institutes of Health (NIH) reported that two experimental vaccines to prevent 2019 coronavirus disease (COVID-19) induce a powerful immune response and quickly control the respiratory tract in the respiratory monkeys exposed to CO-Co-SARSV-2.
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Cancer Discov: Accidental discovery! Immunotherapy can identify and treat chemotherapy-resistant tumors!
Time of Update: 2020-08-06
they believe the differences in these genes are large enough to train the body's immune system to identify and kill cancer cells that repair the BRCA gene -- opening up an exciting new way to treat cancers that are resistant to existing drugs.
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Nat Commun: New research could help treat brain infections and neurodegenerative diseases.
Time of Update: 2020-08-06
these small glial cells release the unique immune molecule IL-1 alpha, which collects immune cells from the blood to control parasites in the brain.
the researchers determined that small glial cells break up and collect immune cells, called macrophages, to control toxoplasmosis infection.
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World Hepatitis Day, 28 July 2020, the latest research progress on hepatitis.
Time of Update: 2020-08-06
!--.) -29 July 2020 /--- July 28, 2020 is the tenth "World Hepatitis Day" as established by the World Health Organization. to call on the whole society to pay common attention to the prevention and t
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Lancet's paper is detailed! The future of chAdOx1's new crown candidate vaccine is bright.
Time of Update: 2020-08-06
!--Webeditor:page title"--29 July 2020 /--- In a new study, a Phase 1/2 clinical trial of a candidate vaccine for SARS-CoV-2 in the United Kingdom, which causes COVID-19, reported promising early results.
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China's special dermatitis new drug! Pfizer Shutmin (Cliborro): The first non-hormonal external PDE4 inhibitor, approved by the National Drug Administration!
Time of Update: 2020-08-06
Dabitor ® is the world's first and only approved treatment of adults with moderate to severe adhesion dermatitis targeted biologics, to fill the domestic clinical lysacitof, can quickly, significantly, and continuously improve the degree of epithelial and itching symptoms of patients with aspecific dermatitis.
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Scientists map the properties of neutrophils on a single-cell scale.
Time of Update: 2020-08-06
results show that although the heterogeneous cell population defined by single-cell RNA sequencing has a high correlation with the classical morphological credit group as a whole, single-cell sequencing techniques can identify more mature subgroup cell populations with the same morphology and different transcription groups, which increase the understanding of the heterogeneity of the mature granulocytes of bone marrow.
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Vaccines: A method for quickly detecting COVID19.
Time of Update: 2020-08-06
"So the virus can be identified with antibodies against Sars-Cov-2," explained lead author Toni-Luise Meister of the Department of Molecular and Medical Virology at Bochum Ruhr University.
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Lancet's paper is detailed! Phase 2 clinical trialshows that the new new crown candidate vaccine developed in China has great potential.
Time of Update: 2020-08-06
!--:page title"--29(2 ---9) -- A Phase 2 clinical trial in China for the Ad5 vector COVID-19 candidate vaccine in China has shown that the vaccine is safe and induces an immune response, according to
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Respiratory syncytial virus (RSV) innovative drug! AstraZeneca/Sanofinirsevimab: Single injection for up to 5 months of long-lasting protection!
Time of Update: 2020-08-06
results showed that in the RSV epidemic season, in healthy premature infants, nirsevimab single-dose intramuscular injection significantly reduced the treatment and hospitalization rates of lower respiratory tract infections (RSV-LRTI) caused by RSV compared to placebos.
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Nature papers read in detail! In some healthy people, SARS-CoV-2 reactive T cells exist.
Time of Update: 2020-08-06
!--:page title"----- In a new study, researchers from the SchallitSchool School of Medicine in Berlin, Germany, and the Max Planck Institute for Molecular Genetics found that some healthy people have immune cells that recognize the new coronavirus SARS-CoV-2.
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Nature: A single dose of Ad26.COV2.S vaccine has made rhesus monkeys strongly resistant to the new coronavirus.
Time of Update: 2020-08-06
Barouch, an immunologist at the Beth Israel Deacon Medical Center (BIDMC), reported that a leading COVID-19 vaccine developed by BIDMC in collaboration with Johnson and Johnson causes neutralizing antibodies and strongly protects non-human primates from SARS-CoV-2.
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Science: 100-year-old sex parasitic mystery finally solved! Sacrifice immune function in exchange for permanent male and female conjoinedness.
Time of Update: 2020-08-06
"In addition to the removal of this unusual MHC gene, we found that the function of killer T cells that actively remove infected cells or attack foreign tissue during organ rejection is severely impaired, if not completely lost," said Jeremy Swann of the Max Planck Institute for Immunobiology and Epigenetics, the first author of the paper.
