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Lupus patients got cancer after taking this medicine
Time of Update: 2021-04-23
Another possibility in this case is that the patient already had renal cell carcinoma during the active stage of lupus nephritis, but the latter was not detected by ultrasound, and subsequent cyclophosphamide treatment may accelerate the growth of the cancer.
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Neurology: Vitamin D, smoking and EBV can predict long-term cognitive function in patients with multiple sclerosis
Time of Update: 2021-04-23
In the new study, the researchers extended the follow-up period to 11 years, and examined whether vitamin D, smoking, and anti-EBNA-1 antibodies can help predict long-term cognitive function and axons early after the first manifestation of relapsing-remitting MS For completeness, the research results have been published in Neurology.
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worth collecting! How to manage the 4 stages of gout well to avoid recurring attacks? The article "The Lancet" is clear
Time of Update: 2021-04-23
Urate-lowering therapy is usually recommended for the following patients: appearance of tophi, imaging evidence of joint damage caused by gout, frequent attacks of gout (≥2 times within a year) and urinary tract stones; high serum uric acid concentration (> 480 µmol/L) ) Or young patients (<40 years old) with comorbid diseases (kidney or heart disease).
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Why does imaging progress in patients with rigidity?
Time of Update: 2021-04-23
Studying the progression of AS imaging and its characteristics, and exploring its pathological bone remodeling mechanism is of great significance to the early diagnosis and treatment of the disease.
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Tips: What is rheumatic fever?
Time of Update: 2021-04-23
Symptoms pericardial scar endocardium myocardiumThe inflammatory lesions of rheumatic fever involve the collagen fibers of the connective tissues of the whole body.
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How to choose medication for acute gout attacks?
Time of Update: 2021-04-23
According to the "2016 Chinese Gout Diagnosis and Treatment Guidelines", there are three types of drugs to choose from during the acute attack: colchicine, non-steroidal anti-inflammatory drugs, and glucocorticoids.
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For these patients at high risk of AS structural damage, the long-term benefits of treatment are the key!
Time of Update: 2021-04-23
A number of studies have explored the predictive factors of long-term structural damage in AS, which may bring new inspiration for clinical treatment.
A number of studies have explored the predictive factors of long-term structural damage in AS, which may bring new inspiration for clinical treatment.
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Sub-Journal of "Nature": High-fructose diet damages the immune system!
Time of Update: 2021-04-23
The researchers first determined that the phenotype of bone marrow-derived macrophages (BMDMs) in mice is similar to that of human monocytes, and that they can also exhibit consistent metabolic changes and increased expression of pro-inflammatory cytokines under fructose culture.
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Real-world therapeutic research of systemic lupus erythematosus
Time of Update: 2021-04-23
SLE is a very complex disease, and a clear treatment goal can help doctors adjust the treatment plan in a targeted manner during follow-up.
This time, we will share the real-world treatment research of SLE patients collected by the CSTAR database.
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Research discovers new mechanisms to improve antibody response rate and vaccine protection
Time of Update: 2021-04-22
The study found that granular antigens such as hepatitis B vaccine specifically induce a type of macrophages in lymph nodes, medullary sinus macrophages (MSM), to produce a kind of interleukin-1 receptor antagonist (IL- 1Ra) cytokines are the "culprit" that inhibits the production of high levels of antibodies by B cells.
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Terrible!
Time of Update: 2021-04-22
In food allergies, the body will treat certain proteins such as casein and whey in milk as invaders and cause an immune response.
cn/ipsen/sporty/show-details/3074/2">digested thereby leading to a series of symptoms, a condition called lactose intolerance can cause bloating, abdominal cramps and Diarrhea, but not life-threatening.
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RA first-line medication, methotrexate vs leflunomide, are you really using it right?
Time of Update: 2021-04-21
For severe liver and kidney damage, alcohol or drug abuse, bone marrow suppression, hepatitis B or hepatitis C virus infection activities Patients in the early stage should avoid the use of MTX.
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Professor Li Zhanguo: Only by doing so can patients with osteoarthritis delay the progression of the disease!
Time of Update: 2021-04-21
Figure 1 The incidence of OA in various provinces in China A multi-center cross-sectional study involving 1066 patients summarized the current status of OA treatment in China.
Patients with joint pain often have indications for the use of disease-modifying osteoarthritis drugs (DMOADs), but currently only 37.
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For the initial treatment of lupus nephritis with glucocorticoids, should I choose a high dose or a medium dose?
Time of Update: 2021-04-21
The results showed that the high-dose group had a higher complete remission rate than the medium-dose group at 12 months (61.
In conclusion, in patients with new-onset LN, a higher initial dose of prednisone (median 45 mg/d) can significantly increase the complete renal response rate at 12 months.
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Immunity | Viruses are diverse, immunity is similar
Time of Update: 2021-04-20
These four modules respectively show the similarities and differences of the immune response between severe and mild viral infections, regardless of whether they are infected with common influenza viruses or new coronaviruses.
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Nature Immunology is heavy!
Time of Update: 2021-04-20
This study clarified in detail the new mechanism of MDM2-STAT5 signal axis regulating T cell-mediated tumor immunology.
At present, there is an urgent need for targeted drugs that can block the MDM2-p53 interaction and enhance T cell-mediated immunity while eliminating tumor cells.
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Both efficacy and safety, suitable for the treatment of Chinese RA patients-the latest phase IV clinical research results announced!
Time of Update: 2021-04-20
Figure 3: Evaluation of the efficacy of IGU at the 12th and 24th week (A) ACR response rate; (B) DAS28 disease activity patient distribution 2 Safety analysis The occurrence of AE, SAE and ADR during the entire study period The rates were 51.
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After using anti-tumor drugs, I did not expect to get rheumatism!
Time of Update: 2021-04-20
He was diagnosed with "myositis, myocarditis" and was given methylprednisolone 80 mg qd intravenous infusion for 16 days, as well as treatments such as heart rate control, liver protection, anti-inflammatory, stomach protection, and blood pressure reduction.
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Nature: Significant progress!
Time of Update: 2021-04-20
The title of the paper is "Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH".
html Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
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When lupus nephritis "runs" high blood pressure, what are the harms?
Time of Update: 2021-04-20
Factors related to poor kidney prognosis include age, genetic characteristics, high serum creatinine, high blood pressure and severe infections.
At the same time, hypertension is an independent risk factor for poor prognosis such as death, end-stage renal disease and doubling of serum creatinine in patients with LN.
