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Nat Commun: Injection of synthetic RNA viruses to treat cancer and address the limitations of oncolytic viruses
Time of Update: 2022-10-12
The research team has developed a completely synthetic RNA virus, Synthetic RNA virus, which delivers the RNA viral genome (vRNA) through lipid nanoparticles (LNP), which will solve the limitations of repeated intravenous administration of oncolytic viruses and improve the therapeutic potential of oncolytic viruses.
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Sci Rep: Worthy of being an "angel in cancer"?
Time of Update: 2022-10-12
86), and a history of thyroid cancer may be a protective factor for liver cancer death in PLC patients (Table 3) .
86), and a history of thyroid cancer may be a protective factor for liver cancer death in PLC patients (Table 3) .
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DCR: Downgraded treatment for advanced rectal cancer – chemotherapy after short-term radiotherapy is an alternative to long-term chemoradiotherapy
Time of Update: 2022-10-12
This study confirmed that short-course radiotherapy + delayed surgery after chemotherapy resulted in decreased T and tumor regression scores compared with long-course chemoradiotherapy, but the pathological periphery, distal resection margin, lymph node rate, and perioperative incidence were similar in both groups.
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Cell: Based on 35 cancer types, the mechanism of cancer-microbial interaction has been discovered
Time of Update: 2022-10-12
On September 29, a study conducted by foreign scientists comparing fungal communities within tumors with matched bacterial and immune groups revealed a co-occurring dual-domain ecology, often with a loose rather than competitive microenvironment and different immune responses.
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A complete review of the nine major drug targets for non-small cell lung cancer
Time of Update: 2022-10-12
At present, EGFR-TKI has developed into the fourth generation, and a total of 8 drugs have been launched .
At present, EGFR-TKI has developed into the fourth generation, and a total of 8 drugs have been launched .
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JEADV: Treatment, curettage or cryopectomy for basal cell carcinoma?
Time of Update: 2022-10-12
Recently, a single-center, non-inferiority clinical trial published aims to compare the effectiveness of curettage and cryotherapy sBCCs in terms of overall clinical clearance and wound healing time after 1 year.
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【Case Sharing】Atypical sarcoidosis
Time of Update: 2022-10-12
4. Pathological examination: granulomatous lesions of cervical lymph nodes, small granulomas, no case-like necrosis, fibroscopy clamping bronchial biopsy: (right upper lobe opening biopsy) chronic inflammation of the mucosa, interstitial fibrous tissue hyperplasia, (brush) no tumor cells (see Figures 5 and 6)5.
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Radiology: Microcalcification and peritumoral edema predict the prognosis of neoadjuvant chemotherapy for Luminal breast cancer
Time of Update: 2022-10-12
10 years after surgery, the patient is still alive without distant metastasesIn this study, predictive models that combined imaging and clinicopathological variables showed good resolution for the prognosis of patients with Luminal breast cancer receiving neoadjuvant chemotherapy.
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Deepening the Impression - A Case of Inflammatory Myofibroblastic Tumor of Esophagus and Gastric
Time of Update: 2022-10-12
CT examination showed that the esophageal wall in the lower esophagus and the gastric wall in the cardia area were significantly thickened unevenly, and the esophageal cavity was narrowed; a mass of high-density shadow was seen at the fundus of the stomach, no tumor grew significantly outside the wall, and no obvious surrounding lymph nodes were found ( Figure C) .
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World J Urol: Evaluation of the effect of gemcitabine-carboplatin and gemcitabine-cisplatin in the treatment of muscle-invasive bladder cancer
Time of Update: 2022-10-12
Sep 2022 Cisplatin chemotherapy is recommended for patients with muscular-invasive bladder cancer (MIBC), followed by radical cystectomy (RC).
Sep 2022 Cisplatin chemotherapy is recommended for patients with muscular-invasive bladder cancer (MIBC), followed by radical cystectomy (RC).
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JEM Fu Yangxin/Peng Hua collaborated to develop a new generation of tumor-specific anti-PD-1-IL-15 immunotherapy drugs
Time of Update: 2022-10-12
As a new method of tumor treatment that has developed rapidly in recent years, tumor immunotherapy has made the situation of tumor treatment look new by mobilizing the body's own immune system to figh
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J Clin Oncol: Toripalimab combined with chemotherapy for the treatment of advanced non-small cell lung cancer
Time of Update: 2022-10-12
Progression-free survival rates in both groupsAt the time of the final PFS analysis, PFS was significantly longer in the Toripalimab group than in the placebo group (median PFS: 8.
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Nature sub-journal: Earlier detection of lung cancer at the cellular level!
Time of Update: 2022-10-12
RELATED: Researchers at the Abramson Cancer Center at the University of Pennsylvania have found a way to identify lung cancers at the cellular level in real time during biopsies, offering hope for earlier, more confident disease detection .
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DCR: Analysis of long-term bowel dysfunction and decreased quality of life in patients after colon cancer surgery
Time of Update: 2022-10-12
The objective of this study was to compare long-term differences in bowel function and quality of life in patients undergoing right or left hemicolectomy or sigmoidectomy.
The objective of this study was to compare long-term differences in bowel function and quality of life in patients undergoing right or left hemicolectomy or sigmoidectomy.
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Recommended reading: Consensus of Chinese female breast cancer prevention experts
Time of Update: 2022-10-12
Guideline name: Expert consensus on breast cancer prevention in Chinese womenEnglish:Publisher: Breast Professional Committee of China Research Hospital AssociationPublished:2022-08-15Brief introducti
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Cell: Not only bacteria, but also fungi are generally lurking in tumors, and they also accelerate the development of cancer?
Time of Update: 2022-10-12
In the first Cell paper, to understand whether fungi have changed in cancer patients, researchers at the Weizmann Institute of Science in Israel and the University of California, San Diego, classified and studied fungi in more than 17,000 tissues and blood samples from 35 cancer types.
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The safety, pharmacokinetics and pharmacodynamics of the cancer drug candidate E-602 invented by Nobel laureates in non-human primates
Time of Update: 2022-10-12
Sialic acid is a special glycan that can be recognized by a range of surface proteins that are found primarily on innate immune cells but also on activated T cells at the tumor site. These proteins, c
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J Clin Oncol: Letrozole plus Abbesilil for recurrent ER-positive endometrial cancer
Time of Update: 2022-10-12
The study is a phase II, two-stage clinical trial designed to evaluate the efficacy and safety of letrozole plus abbesilil in recurrent ER-positive endometrial cancer.
The study is a phase II, two-stage clinical trial designed to evaluate the efficacy and safety of letrozole plus abbesilil in recurrent ER-positive endometrial cancer.
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European Radiology: Which imaging metric enables accurate prediction of invasive breast cancer?
Time of Update: 2022-10-12
Lesion size: front and back (AP), left and right (RL) and up and down (SI)This study shows that the volume doubling time of mammography screening lesions is an important indicator to distinguish benign lesions from invasive breast cancer.
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Nature Metabolism: Qiao Wu's team at Xiamen University revealed a new mechanism by which hepatic stellate cell exohexohrokinase HK1 accelerates the process of liver cancer
Time of Update: 2022-10-12
Hepatocellular carcinoma (HCC) is the most common hepatic malignancy, and more than 80% of clinical liver cancers are developed from liver fibrosis or cirrhosis, suggesting that liver fibrosis can dir
