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Consultation analysis (2022.8.30): Considering the nature of the tumor, multiple nodules in both lungs are also showing back pain, is it a danger signal?
Time of Update: 2022-09-14
Basic information:Female 58 years oldDisease Description:Back pain, chest CT after the discovery of ground glass nodules, please give judgment to the director. Image display and analysis:Let's first l
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With a 5-year survival rate of 84%, the "weapon" of the United States to treat endometrial cancer is precision surgery and rational medication!
Time of Update: 2022-09-14
In January, the New England Journal of Medicine published findings showing that the combination of Keytruda+Lenvima significantly prolonged the survival of patients with advanced endometrial cancer compared with the chemotherapy group 。 Specifically, the median overall survival in the Keytruda+Lenvima group was 18.
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Tumor Infiltrating Lymphocytes (TIL): 6 Questions You Need to Know
Time of Update: 2022-09-14
Tumor-infiltrating lymphocyte (TIL) therapy is an experimental cell therapy under development for the treatment of solid tumors, which has the advantages of multi-target, strong tumor tendency and infiltration ability, and small side effects compared with CAR-T cell therapy and PD-1/PD-L1 antibodies.
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Non-apoptotic regulatory cell death in tumor immunotherapy
Time of Update: 2022-09-14
Recently, several studies have revealed the interaction between non-apoptotic RCDs and anti-tumor immunity, and targeted therapies for autophagy, iron death, cytokewal death, and necrotizing apoptosis combined with immunotherapy may exert powerful anti-tumor activity, even for ICi-resistant tumors.
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"Left auxiliary right bow" bidirectional VISTA immune checkpoint: immunotherapy to the left, autoimmune disease therapy to the right
Time of Update: 2022-09-14
summary The emergence of drug resistance in immune checkpoint therapy highlights the complex variability of tumors and the inadequacy of single-target therapy, and multi-target synergistic therapy ha
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Clin Cancer Res: Introduction of irutinib before Venetok therapy is effective in improving prognosis in patients with chronic lymphocytic leukemia
Time of Update: 2022-09-14
CCR-22-0504 The Phase 2 CAPTIVATE study evaluated the efficacy of irutinib in the first-line treatment of chronic lymphocytic leukemia in two cohorts (randomized treatment termination cohort and fixed course cohort guided by tiny residual lesions).
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Research advances in targeted therapy for tumoroglycans
Time of Update: 2022-09-14
Preliminary results from another phase I/II study evaluating BMS-986012 monotherapy or in combination with nivolumab for patients with relapsed/refractory small cell lung cancer (NCT02247349) showed that this monoclonal antibody was well tolerated and showed antitumor activity in some patients.
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Prototype of checkpoint response in tumor immunotherapy
Time of Update: 2022-09-14
prefaceCurrently, the responsiveness of cancer patients to immune checkpoint blockade (ICB) therapy is predicted by different individual measurements with varying degrees of accuracy, including tumor mutation burden, tumor invasive T cell density, dendritic cell frequency, and checkpoint ligand expression.
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Investigative Radiology: Spatial prediction of TACE postoperative drug dose based on cone beam CT scan
Time of Update: 2022-09-14
Doxorubicin levels in tumor specimens were measured by high performance liquid chromatography and correlated with DEB iodine content measured using the embolization treatment planning software based on prototype cone beam CT.
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【Cell Sub-journal】The latest review study of Professor Fang Jingyuan's team of Shanghai Jiaotong University on the prevention and treatment targets of colorectal cancer
Time of Update: 2022-09-14
Recently, Professor Fang Jingyuan's team from Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine published a latest review in Trends in Microbiology, summarizing the biological characteristics and regulatory mechanisms of the development of Clostridium nucleated bacterium in colorectal cancer (CRC), and using Clostridium nucleated as a marker for early warning and prognosis prediction of CRC.
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Exp Dermatol : Dermatometric features of basal cell carcinoma similar to melanoma
Time of Update: 2022-09-14
The objective of this study was to compare atypical non-facial MMS with atypical basal cell carcinoma characteristics with at least one basal cell carcinoma feature in selected cohorts with melanocyte characteristics to identify dermoscopic features to develop scores that would help with differential diagnosis.
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"Friends into Love" is coming! The first oncologist medical humanities slow variety show was launched
Time of Update: 2022-09-14
"Patient-centric" is increasingly becoming one of the standards by which today's healthcare is measured. How to let patients get more care and respect in the treatment process has become an important
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Viruses can also "hide and seek"! According to studies, carcinogenic viruses evade the immune system and accelerate tumor growth!
Time of Update: 2022-09-14
A team of researchers in Florida State University's Department of Biological Sciences and the Institute of Molecular Biophysics have discovered a mechanism used by cancer-causing viruses to evade immune system responses that typically trigger antiviral responses and viral suppression.
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Advances in tumor immunotherapy research targeting TIGIT
Time of Update: 2022-09-14
In clinical development, the FcγR binding region of anti-TIGIT antibodies is active in some molecules and inactivated in others.
In clinical development, the FcγR binding region of anti-TIGIT antibodies is active in some molecules and inactivated in others.
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Bone and Soft Tissue Tumor NGS China Expert Consensus (2021 Edition)
Time of Update: 2022-09-14
View the original text of the guide: Bone and Soft Tissue Tumor NGS China Expert Consensus (2021 Edition)Want to see more guidelines for sarcoma? Click hereBone and soft tissue tumors are rare tumors,
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Tumor Biology: (13) Invasion and metastasis of tumors
Time of Update: 2022-09-14
6 The key role of extracellular proteasesEMT represents the replication biological process by which cancer cells acquire the ability to invade and motility, which includes a number of important effector molecules, the most important of which is matrix metalloproteinase (MMP).
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Cancer Discov: The mechanism of resistance to alkylated drugs in small cell lung cancer was discovered
Time of Update: 2022-09-14
In previous work, the scientists found that a protein called RNF113A is associated with the ability of cancer cells to repair alkylated damage, a pattern of attack by common chemotherapy drugs.
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[PHILIPS 1 case per day] 1 case of parasellar meningeal periangular cell tumor
Time of Update: 2022-09-14
HPC on CT sweep is mostly leaf-splitting, and the tumor is prone to necrosis and cystic changes, showing high and low mixed density, and rarely calcification; Most mass effects are obvious but the edema is mild, and there may be local bone destruction; After the enhancement scan, there is a significant uneven intensification.
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Braz J Otorhinolaryngol: A cell kinetic marker for squamous cell carcinoma and basal cell carcinoma of the skin of the head and neck
Time of Update: 2022-09-14
The objective of this study was to study the proliferative markers ki67, MCM2 and dionyl proteins in head and neck cutaneous basal cell carcinoma and squamous cell carcinoma.
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The incidence of bowel cancer among young people in South Korea is the highest in the world! My country is close behind
Time of Update: 2022-09-14
This article is the original of translational medicine network, please indicate the source when reprintingAuthor: MiaAccording to data from the Korean Society of Colorectal Disease on Sunday, South Korea has the highest incidence of colon cancer among people in their 20s to 40s in the world.
