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Nat Commun: Oghidini, in conjunction with drug-resistant signal suppression, significantly improves the prognosm of EGFR mutant lung cancer.
Time of Update: 2020-10-04
Map of the potential mechanisms by which oxytinib induces FOXA1 and IGF-1R expression The researchers found that cells with low expression levels of AXL were more sensitive to oxytinib than cells with high expression levels of AXL in EGFR mutant lung cancer (EGFRmut-LC) cells, but Ohithini resistance appeared in a small number of populations.
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The hoarseness test turned out to be throat cancer, and the doctor warned against these symptoms.
Time of Update: 2020-10-04
And for the larger one-sided T2 or T3 sound door throat cancer, some of the patients can also use the oral laser microscopic surgery, but need to remove a wider range of throat tissue, postoperative tissue defects are more, if not repaired in time, after treatment of the pronunciation effect is relatively poor, hoarse voice serious, patients talk laborily and difficult to identify speech content.
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Clin Cancer Res: Antimalarial drug chloroquine increases the sensitivity of GNAQ/11 mutant melanoma to MEK1/2 inhibitors!
Time of Update: 2020-10-04
This study aims to evaluate the role of chloroquine (lysosome inhibitors, antimalarial drugs) or hydroxychloroquine combined MAP kinase pathps to inhibit the effects of GNAQ/11 mutant cells in and outside the body, and to clarify the mechanism of action of MEK1/2 inhibitors combined with chloroquine induced cytotoxicity.
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Real-world research has released the world's first cancer electric field treatment to benefit Chinese patients.
Time of Update: 2020-10-04
On September 12, 2020, at the 4th Annual Meeting and 4th China Cerebral Glioma Academic Conference of the Professional Committee of the Chinese Physicians Association, a forward-looking, one-arm obser
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2020 CSCO Conference opens, wonderful non-stop!
Time of Update: 2020-10-04
Professor Wang Jie of the Oncology Hospital of the Chinese Academy of Medical Sciences interpreted the RATIONALE 307 study: a Phase III study of patients with advanced squamous non-small cell lung cancer treated with pure chemotherapy first-line chemotherapy, which was first published at this year's ASCO Conference and the latest results were presented at this year's ESMO Conference.
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Blood:piRNA-30473 promotes DLBCL occurrence and poor prognosmation by regulating m6A RNA methylation.
Time of Update: 2020-10-04
, the piRNA-30473/WTAP/HK2 axis is involved in the occurrence of DLBCL by regulating m6A RNA methylation.
, using a comprehensive analysis of clinical data and data sets from the study, the researchers found that the m6A regulatory gene piRNA-30473 and WTAP improved survival prediction in DLBCL patients.
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Rongchang Bio-Virdixito monoanti (RC48) treatment of urethra skin cancer was recognized by the FDA breakthrough therapy.
Time of Update: 2020-10-04
the FDA's breakthrough therapy determination means that the clinical data of the new drug show significant efficacy compared to existing treatments, which will accelerate the process of clinical development and meet the needs of patients at an early time.
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J Vasc Surg: 20 years of single-center follow-up results, the first generation of stent cavity repair aneurysm overall results.
Time of Update: 2020-10-04
to explore the prognosis for the first generation of stent implants (Vanguard) to treat patients with abdominal aortic aneurysms (AAA), researchers from Finland shared the results of a 20-year follow-up at a single center.
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CA Cancer J Clin: Revealing the cruel truth that cancer is getting younger! The number of cancer cases among young people has been increasing in the last 10 years.
Time of Update: 2020-10-04
the age group 20-29, the incidence of cancer is 42 and 55 cases per 100,000 population, respectively, and the incidence of cancer among women is 30 per cent higher than that of men.
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Terisha reduced the risk of brain recurrence by 82% in the early EGFR mutation lung cancer-assisted treatment.
Time of Update: 2020-10-04
A preset exploratory analysis of a Phase III ADAURA clinical study based on positive results showed that AstraZeneza's Terisa (chemical name: Ogini Osimertinib, trade name: Terisa Tagrisso) was in the early stages of undergoing a complete tumor excision (Complementary treatment in patients with non-small cell lung cancer (NSCLC) of EGFRm, a prefrontal growth factor change (EGFRm) in IB, II and IIIA periods, can lead to clinically significant improvements in the disease-free survival of the central nervous system (CNS) (DFS).
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Is the smelly chemotherapy life-saving or life-saving? The expert told us the story of a magical mother-of-two...
Time of Update: 2020-10-04
In recent years, tumor has become a hot topic about the treatment of tumor chemotherapy, radiotherapy, surgery are common means of chemotherapy, most people can not help but hair loss, nausea and vomi
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Acta Neuropathologica: C11orf95-RELA reprogrammed the 3D epigenome of the on-screen chamber membrane tumor.
Time of Update: 2020-10-04
paper, the authors' team found that the C11orf95 component of the fusion protein determines DNA binding activity, while the RELA component is necessary to drive gene expression associated with tratermoblastoma.
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NEJM: Oghidini as an EGFR mutation-positive NSCLC postoperative auxiliary therapy, patients significantly benefit.
Time of Update: 2020-10-04
Data updated by 's hypothetical CNS and non-CNS recurrence rates ADAURA studies show that reduced risk of local and distant recurrence, as well as improvements in CNS DFS, further support for Oghidini-assisted therapy as an efficient, practice-changing treatment strategy for EGFR gene mutation-positive I.B.III.A NSCLC patients after tumor complete removal.
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Nat Commun: VAV2 promotes the regenerative proliferation of squamous cell carcinoma in the skin and head and neck.
Time of Update: 2020-10-04
cancer-promoting effects of the VAV2 signal was found by researchers who found that the catalytic dependence and RHO GTPase dependence function were mediated by c-Myc and YAP/TAZ dependent regenerative proliferation and cell non-differentiation-related transcription.
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Lancet oncol: The long-term efficacy of postoperative ancillary therapy for the maintenance of high-risk melanoma is significantly better than that of Ipi monoanti.
Time of Update: 2020-10-04
4-year recurrence-free survival rates in the Navu monoantigroup and the Ipi monoantigroup were 51.7% and 41.2%, respectively (risk ratio of 0.71, 95% CI 0.60-0.86, p=0.0003).
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Medical College Oncology Hospital Zhang Wei: Don't think it's just an aid, it may affect the whole cancer war.
Time of Update: 2020-10-04
"The rate of nausea and vomiting is still relatively high during anti-tumor treatment, and I want more people to know that we already have a lot of good anti-spitting drugs and need to explore a more
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Brit J Cancer: Relationship between antibiotic use and colorectal cancer risk.
Time of Update: 2020-10-04
There have been no studies to report a correlation between oral antibiotics and colorectal cancer (CRC) that varies with the antibiotic spectrum and colorectal cancer type, and whether there is a nonlinear dose-dependent relationship.
the correlation between antibiotic use and CRC risk appears to vary between broad-spectrum and narrow-spectrum antibiotics.
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Clin Cancer Res: The efficacy of the second-generation yew-alkane Kabatsai treatment for metastatic stomach cancer.
Time of Update: 2020-10-04
(effects of HER2 state on the efficacy of kabatha) (effects of M2 macrophage characteristics on the efficacy of kabatha) HER2 amplification or over-expression was associated with increased course control, PFS, and overall survival.
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CSCO 2020 Look: What's the busiest PI, do you know?
Time of Update: 2020-10-04
In the field of oncology in China, gastric cancer experts have "North Shen, South Li" Ya, "North Shen" refers to Professor Shen Lin of Peking University Cancer Hospital, "South Li" refers to The Shanghai Oriental Hospital well-known oncologist, former chairman of CSCO Professor Li Jin.
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Despite the smoke has a second trick, reduce the risk of lung cancer, shaking sound public welfare challenge perfectly closed.
Time of Update: 2020-10-04
In order to promote the concern of all sectors of society on the dangers of tobacco and small cell lung cancer, and to call on the general public, especially young people, to stay away from tobacco an