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World J Urol: Evaluation of the effect of gemcitabine-carboplatin and gemcitabine-cisplatin in the treatment of muscle-invasive bladder cancer

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Cisplatin chemotherapy is recommended for patients with muscular-invasive bladder cancer (MIBC), followed by radical cystectomy (RC

Recently, researchers from the Netherlands published an article in World J Ulol comparing the clinical outcomes of preoperative gem-carbo and gem-carbo after 3 cycles of ≥ treatment

The study included 1865 patients

A total of 747 patients treated with gem-carbo (n=147) and gem-cis (n=600) were included in the

Comparison of overall survival between the two treatment groups

In summary, some MIBC patients who do not meet the conditions for cisplatin use obtain pCR in gem-carbo treatment, and if the patient can undergo ≥ 3 cycles and receive RC treatment, their survival outcomes may be comparable

Original Source:

Sarah M H Einerhand ， Anna J Black ， Homayoun Zargar et al.

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