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Breakthrough itch therapy submits new drug applications for priority review
Time of Update: 2021-01-04
Cara Therapeutics today announced that it has submitted a new drug application (NDA) for Korsuva injections to the FDA to treat severe itching in patients with hemodialysis.
: Cara Therapeutics Submits New Drug Application to U.S. Food and Drug Administration for KORSUVA™ Injection in Hemodialysis Patients with Moderate-to-Severe Pruritus.
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Nature sub-journal interpretation: Cholesterol recycling may help support myelin...
Time of Update: 2021-01-04
It is well known that in diseases such as atherosclerosis, the deposition of cholesterol in blood vessels is harmful, and similar problems occur in neurological diseases such as multiple sclerosis, i
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And Yellow Pharmaceuticals began rolling applications for the listing of the new drug Sovantinib with the FDA
Time of Update: 2021-01-04
Sovantini's new drug listing application is based on two successful clinical studies of stage III neuroendocrine tumors in China, as well as data support for Sovantini's treatment of patients with non-pancreatic and pancreatic neuroendocrine tumors in the United States.
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Advances have been made in the study of seasonal plasticity of the sensory cortical layer in adult animals
Time of Update: 2021-01-03
Robert Naumann, a researcher at the Institute of Brain Cognition and Brain Disease at the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, led a team that integrated inter
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Nature: New research reveals how our brains track where we and others go
Time of Update: 2021-01-03
"Early studies have shown that low-frequency brain waves of inner temporal lobe neurons help rodents track their location as they navigate new places," said Mattias Stangl, co-author of the paper and lead author of the paper and a postdoctoral scholar at Suthana Labs.
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Cell: The lymph nodes are governed by a unique resurgency neuron with immunomodulation potential
Time of Update: 2021-01-03
In the new study, the researchers used a variety of methods, including advanced imaging, retrograde tracing, single-cell RNA sequencing, and photogenetics, to map the connections between neurons, immune cells and other types of cells in the lymph nodes of mice.
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The study revealed the brain mechanisms of audio-visual time integration windows in people with split and autism traits
Time of Update: 2021-01-03
By studying the relationship between audio-visual time integration windows and splitting traits and autism traits between 155 college students, the Chen Chu overseas Chinese Research Group of the Mental Health Key Laboratory of the Institute of Psychology of the Chinese Academy of Sciences collected data on static magnetic function imaging, and initially explored the brain function connection patterns related to audio-visual time integration capabilities.
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Nature sub-journal interpretation! Cholesterol recycling may help support myelin repair!
Time of Update: 2021-01-03
December 29, 2020 // -- It is well known that cholesterol deposition in blood vessels is harmful in diseases such as atherosclerosis, and similar problems occur in neurological diseases such as multip
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Rare new drug for children with epilepsy! Fintepla is approved by the European Union to treat patients with ≥-year-old Dravet syndrome!
Time of Update: 2021-01-03
results showed that fintepla significantly reduced the frequency of monthly convulsive seizures (convulsive seizures, CS) compared to placebos in patients who took one or more anti-epileptic drugs that did not adequately control seizures.
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First oral new drug for bladder overactive disorder (OAB) in nearly 10 years! Beta 3 epinephrine-estory agonist Gemtesa is FDA approved!
Time of Update: 2021-01-03
December 24, 2020 // -- Urovant Sciences recently announced that the U.S. Food and Drug Administration (FDA) has approved a daily 75 mg Gemtesa (vibegron, Vibergron) for the treatment of patients with urgency urinary incontinence (UUI), uremia, and frequent urethra (OAB).
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December 18, 2020 Science Journal Essence
Time of Update: 2021-01-03
Revealing new mechanisms that mediate microRNA degradation, it is expected to lead to the development of new treatments for a variety of diseases: 10.1126/science.abc9546 In a new study, researchers from the University of Texas Southwestern Medical Center have discovered a mechanism by which cells degrade tiny RNA (microRNA, miRNA), a genetic molecule that regulates the amount of protein in cells.
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Nature Take Stock: Top 10 Life Sciences Cover Articles for 2020
Time of Update: 2021-01-02
researchers found that the loss of P53 could cause miR-34a to be missing from the vesicles secreted by tumor cells in head and neck cancer, allowing cancer-related sensational neurons to be reprogrammed as epinephrine-energy neurons to promote tumor growth.
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Cell Death Differ: The absence of TfR2 in Parkinson's models has a neuropersonal protective effect
Time of Update: 2021-01-02
TfR2 deficiency has a protective effect on mice treated with 52-week-old mptp, reducing iron load by chelation has been considered a viable treatment strategy for disease improvement.
researchers have found that the absence of TfR2 can act as a nerve protection by fighting dopamine neuron degeneration, PD, and iron overload associated with aging.
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The European Union approved Findepla for the treatment of Dravet syndrome
Time of Update: 2021-01-02
European Commission (EC) has approved Zogenix's Fentepla (fenfluoramine) for the treatment of seizures associated with Dravet syndrome, and Fintepla as an additional therapy for other anti-epileptic drugs.
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New medicine for nerve pain! The first three total Tarlige (mirogabalin) treatment of spinal cord injury after the central nervous pathological pain phase 3 clinical success!
Time of Update: 2021-01-02
December 28, 2020 // -- Daiichi Sankyo, a Japanese pharmaceutical company, recently announced that a Phase 3 study to assess the treatment of spinal cord injury (SCI) by Mirogabalin has reached its main end.
() Original source: Daiichi Sankyo Announces Phase 3 Study Results of mirogabalin of central neuropathic pain after spinal cord injury
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The study found that individual differences in the average gaze time in the first round of reading were associated with resting function connections
Time of Update: 2021-01-02
li Xingshan, a researcher at the Key Laboratory of Behavioral Science of the Chinese Academy of Sciences, studied the problem and used eye tracking and resting magnetic resonance imaging to explore the correlation between the first round average gaze time of an individual in chapter reading and the connection of individual resting state function.
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JNNP: Neuropathy Around ALS: Esothypetic Association
Time of Update: 2021-01-02
in a multi-center study, 88 ALS patients were surveyed, 12.5 percent of whom developed sensory multiple neuropathy (PNP), independent of age, course and site of onset.
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Metab Eng: Treat Parkinson's with tomatoes? British scientists have developed an improved version of tomatoes that could be a source of drugs for Parkinson's disease
Time of Update: 2021-01-02
Cathie Martin, a professor in the Department of Metabolic Biology and Biochemistry at Norwich Research Park in the UK, and her co-partners recently developed a genetically modified tomato that could provide a drug for Parkinson's disease.
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Lancet Psychiatry |。 One million people found that statin use was not associated with suicide, anxiety or seizures
Time of Update: 2021-01-02
addition, the use of statins alone (i.e., not assisted SSRI treatment) may have protective effects on depression, psychiatric hospitalization, and suicidal behavior, but the results are inconsistent.
significance of this study is that the use of statins is not associated with suicide, anxiety or seizures.
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Lancet: Migraines! The Lancet's latest article reveals that Remegis is safe and effective in preventing migraines
Time of Update: 2021-01-02
team conducted a multicenter, randomized, double-blind, placebo-controlled trial at 92 research centers in the United States to assess the safety and effectiveness of remegis in migraine prevention treatment.
