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Lupus: Bellevue single against PK Tattisip, who can win?
Time of Update: 2020-05-29
Systemic lupus is a complex systemic autoimmune disease with diverse clinical manifestations, including large-scale red rash, fever, pain, often leading to multi-organ, multi-system damage, is a ma
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Phase III ADVANCE Study on Otezla's Treatment of Mild Moderate Plaque Psoriasis: Positive Results
Time of Update: 2020-05-29
Amgen announced today that the ADVANCE trial, a multicenter, randomized, placebo-controlled, double-blind Phase III study designed to assess the effectiveness and safety of Otezla ® (apremilast) tr
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Ann Rheum Dis: Long-term efficacy and safety of Sukindan resistance to refractory macauca mucosa and joint phenotypes
Time of Update: 2020-05-29
The study was designed to assess the efficacy and safety of Sukindan resistance to patients with white plug disease mucosa and joint phenomenades that are resistant to conventional and biological t
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Ann Rheum Dis: Initial joint use of Alyson Tan and Dallanon to treat connective tissue disease-associated pulmonary hypertension (CTD-PAH)
Time of Update: 2020-05-29
The study was designed to assess the effectiveness of the initial combination therapy (COMB), as well as baseline characteristics and risk stratification, in the primary group of connective tissue
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Arthritis Rheumatol: The efficacy and safety of the new JAK3/TEC inhibitor PF-06651600 (ritlecitinib) for moderate to severe rheumatoid arthritis
Time of Update: 2020-05-29
The 2a-phase, eight-week double-blind parallel group study assessed the efficacy and safety of PF-06651600 (ritlecitinib) in patients with rheumatoid arthritis (RA), a nonverse inhibitor in the fam
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Gastroenterology: Microcolitis and Risk of Inflammatory Bowel Disease
Time of Update: 2020-05-29
Colitis under the microscope has a common mechanism for causing disease with inflammatory bowel disease (IBD) Researchers recently used data from a national queue study to examine the relationship
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Ann Rheum Dis: Ultra-early randomized controlled trial using Inasip and MTX vs MTX in combination with Inasip delayed treatment ra
Time of Update: 2020-05-29
This study was designed to confirm that methotrexate in the methotrexate ( ETN-MTX ) is better than MTX targeted therapy ( MTX-TT ) in the ultra-early stage of rheumatoid arthritis ( ERA ) ( 30%
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J Rheumatol: The Challenge of Very Early Systemic Sclerosis: A Mix of Mild and Early Diseases?
Time of Update: 2020-05-29
In order to address the hypothesis that very early systemic sclerosis (SSc) is a group of mild or early patients with heterogeneousness, the degree of heterogeneity in clinical, epidemiological, an
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Ann Rheum Dis: The efficacy and safety of hedonist mono-anti-subcutaneous administration to treat hip or knee osteoarthritis
Time of Update: 2020-05-29
In a study that included 24 weeks of treatment and 24 weeks of safe follow-up, the efficacy of neurogrowth factor inhibitors, tanyzumab, for the treatment of hip or knee osteoarthritis (OA) was ana
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J Rheumatol: rituximaandaandiphosphamide therapy antisynthetic syndrome associated with ILD
Time of Update: 2020-05-29
Anti-synthetic enzyme syndrome (ASyS) correlation interstitial pulmonary disease (ILD) has a poor prognosis Intravenous cyclophosphamide (CYC) and rituxima (RTX) are the main treatments for moderat
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Nano Lett: Nanostructure surfaces with different elastic modules regulate the immune response by stretching macrophages
Time of Update: 2020-05-29
Reasonable immune response is the key to the successful implantation of biological materials into the human body, and the design and manufacture of biomaterials to regulate immune response is the f
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Ann Rheum Dis: High prevalence of postpartum arthritis-like MRI lesions in women
Time of Update: 2020-05-29
Bone marrow edema (BMO) on MRI of the sic) joint (SIJs) is a hallmark of the central axis spinal arthritis (SpA), but this injury occurs in healthy subjects in the event of increased mechanical str
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NATURE: Bohai/Zhong Yi/Hu Wei Group Joint Discovery: Brain-Spleen Axis Directly Regulates Vaccine-mediated Antibody Immune Response
Time of Update: 2020-05-29
It has been speculated that brain activity may directly control the adaptive immune response of lymphatic organs, but so far there is little evidence of this recently, researchers in China found
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Ann Rheum Dis: Is rheumatoid arthritis targeted therapy really effective? Patient Queue Longitudinal Analysis (RA BIODAM)
Time of Update: 2020-05-29
The study aims to explore whether the goal of targeting ( T2T ) strategies in daily clinical practice can lead to more patients with rheumatoid arthritis ( RA ) to achieve remission goals a dis
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Takeda's Vidoju mono-resistance is approved in China for the treatment of moderate to severe active ulcerative colitis and Crohn's disease
Time of Update: 2020-05-29
Takeda Pharmaceuticals announced that its Entyvio (Vidoju mono-resistance) is approved by the China Drug Administration (NMPA) for the treatment of adult patients with moderate to severe active ulc
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Ann Rheum Dis: Breast cancer risk and the effects of hormone factors before and after rheumatoid arthritis
Time of Update: 2020-05-29
The study aims to explore the risk of breast cancer in women with rheumatoid arthritis (RA) and the risk of RA in women with a history of breast cancer, taking into account anti-hormonal therapy fo
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Ann Rheum Dis: The Financial Burden of Rheumatoid Arthritis
Time of Update: 2020-05-29
Over the past few decades, the treatment of rheumatoid arthritis (RA) has made rapid progress In particular, the emergence of biological and targeted synthetic diseases to improve the presence of a
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J Rheumatol: Serum miRNA markers as diagnostic and therapeutic markers for psoriasis arthritis
Time of Update: 2020-05-29
MicroRNAs (miRNAs) are small endogenous regulatory RNA molecules that are now potential autoimmune therapy targets and biomarkers The study looked at serum miRNA levels in patients with psoriasis a
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J Thromb Haemost: Antiphospholipid syndrome and the relationship between laboratory positive scant and NBTE prevalence
Time of Update: 2020-05-29
Non-bacterial thrombosis endocarditis (NBTE) is a potential complication of antiphospholipid syndrome (APS) in the form of non-infectious lesions of one or more heart valves There are very limited
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Ann Rheum Dis: Targeted therapy can improve the efficacy of multi-joint early-childhood iade arthritis
Time of Update: 2020-05-29
Childhood iade arthritis is one of the most common chronic inflammatory diseases in children There is evidence that early and effective treatment can minimize the burden of disease in childhood and
