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Does the intestinal flora aggravate osteoarthritis? Cyclophosphamide cures disease or causes cancer? A week of "wind" clouds.
Time of Update: 2020-07-22
in a study involving 1427 patients with OA, the relative and absolute abundance of Streptococcus species in fecal microbiota samples were associated with the severity of OA disease and the increased knee pain associated with OA.
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Plant Cell. A new mechanism for the control of immunity in plant pores.
Time of Update: 2020-07-21
In conclusion, sif2 participates in ABA and flg22 mediated stomatal closure through interaction and phosphorylation with the anion channel slac1 of guard cells, thus playing a key role in stomatal immunity of plants to bacteria.
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Heavy! After the Ice Bucket Challenge, then lift the craze, smile pass waiting for you to relay!
Time of Update: 2020-07-21
since the world smile day was launched, people, patients, doctors and other people from all walks of life have passed on their smiles by sharing smiling posters on social media, appealing to the community to pay attention to scleroderma.
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Nature Highlights . . . Antibody salivary acid modification affects allergic reactions.
Time of Update: 2020-07-21
the authors used mass spectrometry to analyze the N-glycan modification of IgE in these samples, and finally found that sialylation of allergic IgE increased specifically.
allergic reactions can be alleviated by removing sialic acid from IgE or by treating with desialylated glycoprotein.
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Nature Plants . . . The team of Tsuda, a Japanese professor at Huazhong Agricultural University, used in situ bacterial transcription and proteomics in plants to identify pathogen proteins attacked by the immune system!
Time of Update: 2020-07-21
Professor, School of plant science and technology, State Key Laboratory of agricultural microbiology, Huazhong Agricultural University, and independent PI Kenichi Tsuda of Mapu Plant Breeding Research Institute are the corresponding authors of the paper.
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Suffering from "rheumatoid arthritis" for 2 years, 26-year-old I almost died suddenly. Wind list is finalized.
Time of Update: 2020-07-21
some scholars believe that the increased risk of acute coronary syndrome (ACS) in SLE patients is associated with obesity, dyslipidemia, hypertension, type 2 diabetes, sedentary lifestyle, male, smoking, old age, hyperhomocysteinemia, renal insufficiency, family history of coronary heart disease and antiphospholipid antibodies.
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There have been "Reynolds phenomenon", is sudden lower limb numbness, urination difficulties, this is the dragonfly?
Time of Update: 2020-07-21
Figure 1 physical examination showed swelling of hands, ulcer of fingertips, patchy brown rash and pigmentation on both lower limbs.
Fig. 2 pathological biopsy of skin rash ▎ immunological indexes are as follows: correct answer: mixed connective tissue disease (MCTD).
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Uric acid high gout, low depression? People with psoriasis arthritis are eating this way!
Time of Update: 2020-07-21
recently, a study published in Arts Research & amp; therapy showed that low serum uric acid levels were associated with the prevalence of depression in the elderly.
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Treatment of gout, 7 types of situation hasten to take medication, 3 types of food to eat less! Guide time.
Time of Update: 2020-07-21
(level of evidence: medium) for those who can not achieve Su standard after xoi, uric acid excretion drugs and other interventions, but gout attacks are not frequent (< 2 times / year) and there is no subcutaneous gout stone, it is strongly recommended to continue the current ult treatment scheme instead of converting to peglotase treatment.
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Systemic lupus patients, what are the characteristics of men and women?
Time of Update: 2020-07-21
Is gender related to the clinical manifestations and prognosis of systemic lupus erythematosus?
There is a significant gender difference in incidence.
Comparison of clinical characteristics of male and female patients with systemic lupus erythematosus in child-bearing age.
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New Phytol. The Chinese Agricultural University, in collaboration with the French Academy of Agricultural Sciences, has revealed a new mechanism for root knot nematodes to inhibit plant immune response.
Time of Update: 2020-07-21
Recently, Professor Jian Heng of China Agricultural University and Professor Pierre abad of Sophia Institute of agricultural biotechnology, French Academy of Agricultural Sciences, published the "root knot nematode effector mipdi1 targets a stress associated protein, SAP", To establish disease in Solanaceae and Arabidopsis "revealed the molecular mechanism of Meloidogyne incognita inhibiting plant immune response and enhancing its parasitism by secreting effector mipdi1.
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Worried about knee osteoarthritis, try these exercises?!
Time of Update: 2020-07-21
Alison Chang, the author of the study, said: "our findings convey a welcome message that people at high risk of knee OA can safely engage in moderate intensity long-term vigorous exercise to improve their overall health.
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How is systemic sclerosis treated? 4 pictures to fix! . . . you "drugs" know.
Time of Update: 2020-07-21
sildenafil is recommended for the treatment of SSC related pulmonary hypertension in Europe, with an initial dose of 20mg, three times a day.
after half a year to one year of treatment, most of the skin sclerosis will be improved, and the frequency of renal crisis and progressive lung involvement may be reduced.
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"Guidelines for primary diagnosis and treatment of gout and hyperuric acid (2019)" was published! Guide sharing.
Time of Update: 2020-07-21
Suggestions of antiuricemic drug treatment: ① for gout patients who meet the following clinical conditions, we can start drug uric acid lowering therapy (special note: we need to pay attention to the adverse reactions of uric acid reducing drugs): ➤ gouty arthritis attacks ≥ 2 times / year.
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These 20 common rheumatic syndromes, some even doctors do not know?!
Time of Update: 2020-07-21
You should not be aware of the common rheumatic syndrome.
there are many common syndromes in rheumatology department.
Xiaobian will rheumatology doctors need to be familiar with the daily work of 20 classic syndrome sorting, love to learn you quickly collect it!
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The Team Dong Chen of Tsinghua University and others reported in Immunity on the body fluids and cell immunity caused by the new coronavirus.
Time of Update: 2020-07-21
This article is reprinted by emmeck, source: Center for advanced innovation in structural biology, May 6, 2020 / emedclub news News / - the team of Dong Chen (cooperative PI), the team of Chen Fang of
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How to interpret CTD-ILD, 2018 Edition Expert Consensus (next paragraph)?
Time of Update: 2020-07-21
Six problems to be solved and new progress in diagnosis and treatment are combined by expert group For the research results and development trend in the field of ctd-ild, a prospective cohort registration database of ctd-ild should be established on the basis of national multi center and multi-disciplinary cooperation, so as to further carry out evidence-based medicine and real-world clinical research, and solve the following important problems in clinical practice.
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Latest! What is the progress of the stratification and treatment of dry syndrome? EULAR 2020.
Time of Update: 2020-07-21
at the meeting, Professor Thomas D ü rner from Berlin, Germany, introduced in detail the 52 week phase 2B randomized double-blind placebo clinical study of anti BAFF receptor monoclonal antibody ianalumab (vay736) in the treatment of Sjogren's syndrome, mainly defining the dosage, clinical efficacy and safety.
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The Nat Comm-Channing team published the results of the new multivalent cervical cancer vaccine.
Time of Update: 2020-07-21
Persistent infection of human papillomavirus (HPV) can lead to proliferative lesions of epithelial tissues and a variety of benign and malignant tumors. more than 200 types of HPV have been identified
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The immunoasive profile of leukemia predicts the benefits of drug resistance and immunotherapy.
Time of Update: 2020-07-21
By analyzing 442 samples from three groups of children and adults with acute myeloid leukemia (AML), the researchers identified a new immune category for the disease, which can predict the possibility of drug resistance and positive response to immunotherapy.
