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[Cell] "I'm not sick if I don't eat it cleanly", the reason why rural residents have less food allergies is...
Time of Update: 2021-03-25
Researchers found that in the modern environment, there are unnatural substances (including processing Food) or environmental chemicals (such as dishwashing detergents), as well as the absence of natural microbial exposure, all have an impact on the destruction of this food quality control plan, which lays the foundation for the future treatment or prevention of food allergies.
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Rheumatism makes you diagnose, will you?
Time of Update: 2021-03-25
Figure 6 Liver biopsy results for this patient, Professor Liu Yanying emphasized that although the clinical manifestations resemble lupus erythematosus, but the symptoms of immune disease are not typical and there is no obvious improvement after treatment, it is necessary to consider whether it is other diseases Up.
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System inventory | In 2020, Cao Xuetao’s team published 6 research results/reviews, making significant progress in the field of immunology
Time of Update: 2021-03-25
On December 15, 2020, Xuetao Cao’s team published online research results titled Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation on Immunity.
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Cell: "New Coronary Pneumonia Single Cell Research China Alliance" Reveals the Immunological Features of New Coronary Pneumonia
Time of Update: 2021-03-25
This study also lays the foundation for the analysis of the impact of the severity of new coronary pneumonia, the stage of disease, age, gender, and other technical factors on the composition of immune cells in the peripheral blood of the body.
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Can rheumatism patients who take hormones and immunosuppressants get the new crown vaccine?
Time of Update: 2021-03-25
Due to the imbalance of the autoimmune system and the use of glucocorticoids, immunosuppressants or other biological agents and targeted drugs to suppress immune and inflammatory reactions, patients with rheumatic immune diseases will have reduced defenses against pathogens and may be more susceptible to infection New coronavirus, and the risk of serious complications after infection is higher, so more attention should be paid to the issue of vaccination.
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【New Phytol】Shanghai Normal University reveals that peptides play an important role in plant immune response
Time of Update: 2021-03-25
Recently, Meng Xiangzong’s research group at Shanghai Normal University published a research paper entitled Perception of the pathogen-induced peptide RGF7 by the receptor-like kinases RGI4 and RGI5 triggers innate immunity in Arabidopsis thaliana on New Phytologist, revealing the secretion of Arabidopsis thaliana.
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Promote the individualized chronic disease management of RA from four dimensions to achieve "long-term security"
Time of Update: 2021-03-25
prevalence and risk factors of major comorbidities in Chinese patients with rheumatoid arthritis[J].
Introduction and prevalence of remission in Chinese patients with rheumatoid arthritis[J] .
Expert consensus on chronic disease management of patients with rheumatoid arthritis (2014 edition)[J].
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8+ T cell receptor diversity analysis
Time of Update: 2021-03-25
Figure 4 Calculate the diversity index on each TCR chain of the TCGA tumor sample and compare it with the modeled entropy measure 4.
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NC | Significant discovery!
Time of Update: 2021-03-25
More importantly, the authors screened out the Fusarium proteome-encoding SCOOP-like sequence through comparison, and synthesized the corresponding small peptides for induction, and found that the pathogen produced a dependent immune response to MIK2.
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"Nature": Tsinghua Professor Qi Hai's research group reported a new mechanism for high-affinity antibody screening
Time of Update: 2021-03-25
Researchers in the Qihai group speculated that there may be a mechanism that selectively promotes the collision of T cells and high-affinity B cells, thereby increasing the efficiency of antibody affinity maturation.
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How difficult is it to diagnose rheumatism?
Time of Update: 2021-03-25
Case characteristics: The patient’s kidneys were large in appearance, right kidney hamartoma, suggesting occult renal insufficiency; elevated IgG4 and hypocomplementemia; multiple lymphadenopathy; bilateral inguinal masses without obvious cause, progressive increase Da et al; (For details, please click "The increase in blood creatinine, the inguinal lymph nodes are getting bigger and bigger, and it turned out to be.
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[Nature] Stanford scientists revealed that the key to reversing cognitive decline is an immune cell related to inflammation
Time of Update: 2021-03-25
This article is converted Medicine original, reproduced please indicate the source Author: Yun Introduction: Recent "Nature" journal published a research paper from the Stanford University School of Medicine, the scientists pointed out that aging affects the brain, a key factor in cognitive decline It is a macrophage-a type of immune cell related to inflammation.
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Nature issued an article: Faced with the mutation of the new coronavirus, the human body's immune system is constantly responding to evolution!
Time of Update: 2021-03-25
2 Within months, although the neutralizing activity of antibodies in body fluids was significantly reduced, memory B cells continued to evolve to produce somatic hypermutations, expressing antibodies with enhanced efficacy and resistance to RBD mutations, and humoral immunity has been continuously developing.
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Plant Cell | Zhang Yuelin/Ivo Feussner collaborates to reveal the mechanism by which the glycosyltransferase UGT76B1 regulates plant immunity
Time of Update: 2021-03-25
Figure 1 Biosynthesis of NHP-OGlc Recently, Zhang Yuelin's research group from the University of British Columbia and Ivo Feussner's research group from the University of Goettingen in Germany jointly published an online article entitled The glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid in The Plant Cell.
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Cell Sub-Journal: You Fuping's team reveals a new mechanism of mitochondrial protein involved in antiviral innate immunity
Time of Update: 2021-03-25
On January 19, 2021, You Fuping team from the Institute of Systems Biomedicine, Peking University Health Science Center published a research paper entitled "The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling" in Cell Reports, reporting The mitochondrial protein ERAL1 is involved in the regulation of anti-RNA virus innate immunity.
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PNAS: GCGR antibody turns pancreatic islet α cells into β cells to restore insulin...
Time of Update: 2021-03-25
In this study, scientists induced diabetes in mice, triggering the death of insulin-producing cells in the mouse pancreas (using the PANIC-ATTAC model, which can selectively induce caspase-8-mediated pancreatic β-cell apoptosis ).
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Is gyrching curable? Experts say it's |! Take stock of 2020
Time of Update: 2021-03-25
Most gout guidelines do not recommend the use of uric acid lowering drugs at the beginning of the acute attack of gout.
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How does the human body "remember" the new coronavirus | "Nature" paper
Time of Update: 2021-03-25
The authors concluded that the continued existence and evolution of memory B cells indicate that when SARS-CoV-2 reinfection occurs, the human body may quickly produce powerful virus-neutralizing antibodies.
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Qi Hai, the new dean of Tsinghua Medical College, re-published Nature, reporting a new mechanism for high-affinity antibody screening
Time of Update: 2021-03-25
The research team speculated that there may be a mechanism that selectively promotes the collision of T cells and high-affinity B cells, thereby increasing the efficiency of antibody affinity maturation.
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The "14th Five-Year Plan" is here! The overall promotion of the construction of a healthy China depends on these six points
Time of Update: 2021-03-25
Improve public health service projects, expand the national immunization program, and strengthen chronic disease prevention, early screening and comprehensive intervention.
