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The communication of information between plants and the environment, and within and between plants is essential for plant growth and development.
External information transmits extracellular signals into the cell through a systematic cascade reaction, and the cell responds quickly.
Receptor-like kinases are signal molecules in plant growth and development, hormone signal transmission, and biotic and abiotic stress responses.
The plant genome encodes hundreds of receptor kinases and small peptides, but the number of known plant receptor-ligand pairs is limited.
LRR-RK MALE DISCOVERER 1-INTERACTING RECEPTOR LIKE KINASE 2 (MIK2) is a type of receptor kinase.
It was initially identified in pollen tube elongation mediated by AtLURE1 small peptide signal.
AtMIK2 has been shown to interact with MDIS1 and is therefore proposed as part of the AtLURE1 peptide receptor complex.
But another kind of receptor kinase PRK6 (POLLEN-SPECIFIC RECEPTOR-LIKE KINASE 6) and its related proteins have been shown to be involved in AtLURE1 perception.
Next, structural and biochemical studies showed that AtLURE1 binds to PRK6, but not MIK26, and recently confirmed the genetic role of PRK6 in AtLURE1 perception.
These findings question whether AtLURE1 is a potential ligand for the MDIS1-MIK2 complex.
Recently, researchers have discovered that MIK2 is involved in other physiological processes, such as stress response when cell wall damage, salt tolerance to the vascular fungal pathogen Fusarium, root growth and resistance, etc.
, are not involved in AtLURE1, so MIK2 ligand The identity and source are still unknown.Recently, the University of East Anglia in the United Kingdom published an article titled "Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2" online in Nature communications.
This article revealed that Arabidopsis thaliana-rich leucine repeat receptor kinase LRR-RK (MIK2) is a receptor for serine-rich endogenous peptide (SCOOP) plant cytokines.
MIK2 is necessary and sufficient for the immune response triggered by multiple SCOOP peptides, which indicates that MIK2 is the receptor of this diverse peptide family.
The author verified in tobacco that the SCOOP12 peptide can directly bind to MIK2 and trigger the formation of a complex between MIK2 and BAK1 co-receptors.
This shows that MIK2 is necessary for resistance to the root pathogen Fusarium.
More importantly, the authors screened out the Fusarium proteome-encoding SCOOP-like sequence through comparison, and synthesized the corresponding small peptides for induction, and found that the pathogen produced a dependent immune response to MIK2.
These results indicate that MIK2 may recognize the SCOOP-like sequence derived from Fusarium to induce immunity against Fusarium.
So SCOOP is defined as MIK2 ligand.
The identification of MIK2 ligands will help clarify the multiple roles of MIK2 in plant growth, development and stress response.
Figure 1.
SCOOP12 induces the formation of MIK2-BAK1 complex Figure 2.
Different SCOOP peptides induce MIK2-dependent response Original link: https:// Plant Biotechnology Pbj Exchange In order to more effectively help the vast number of scientific researchers to obtain relevant information, Plant Biotechnology Pbj has established a WeChat group, Plant Biotechnology Journal submissions and document-related questions, public account release content and public account submission questions will be concentrated in the group for answers , And at the same time encourage academic exchanges and collision thinking within the group. In order to ensure a good discussion environment in the group, please add the editor WeChat first, scan the QR code to add, and then we will promptly invite you to join the group.
Tips: When adding the editor WeChat and after joining the group, please be sure to note the school or unit + name, and the PI should be noted at the end, and we will invite you to join the PI group.
External information transmits extracellular signals into the cell through a systematic cascade reaction, and the cell responds quickly.
Receptor-like kinases are signal molecules in plant growth and development, hormone signal transmission, and biotic and abiotic stress responses.
The plant genome encodes hundreds of receptor kinases and small peptides, but the number of known plant receptor-ligand pairs is limited.
LRR-RK MALE DISCOVERER 1-INTERACTING RECEPTOR LIKE KINASE 2 (MIK2) is a type of receptor kinase.
It was initially identified in pollen tube elongation mediated by AtLURE1 small peptide signal.
AtMIK2 has been shown to interact with MDIS1 and is therefore proposed as part of the AtLURE1 peptide receptor complex.
But another kind of receptor kinase PRK6 (POLLEN-SPECIFIC RECEPTOR-LIKE KINASE 6) and its related proteins have been shown to be involved in AtLURE1 perception.
Next, structural and biochemical studies showed that AtLURE1 binds to PRK6, but not MIK26, and recently confirmed the genetic role of PRK6 in AtLURE1 perception.
These findings question whether AtLURE1 is a potential ligand for the MDIS1-MIK2 complex.
Recently, researchers have discovered that MIK2 is involved in other physiological processes, such as stress response when cell wall damage, salt tolerance to the vascular fungal pathogen Fusarium, root growth and resistance, etc.
, are not involved in AtLURE1, so MIK2 ligand The identity and source are still unknown.Recently, the University of East Anglia in the United Kingdom published an article titled "Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2" online in Nature communications.
This article revealed that Arabidopsis thaliana-rich leucine repeat receptor kinase LRR-RK (MIK2) is a receptor for serine-rich endogenous peptide (SCOOP) plant cytokines.
MIK2 is necessary and sufficient for the immune response triggered by multiple SCOOP peptides, which indicates that MIK2 is the receptor of this diverse peptide family.
The author verified in tobacco that the SCOOP12 peptide can directly bind to MIK2 and trigger the formation of a complex between MIK2 and BAK1 co-receptors.
This shows that MIK2 is necessary for resistance to the root pathogen Fusarium.
More importantly, the authors screened out the Fusarium proteome-encoding SCOOP-like sequence through comparison, and synthesized the corresponding small peptides for induction, and found that the pathogen produced a dependent immune response to MIK2.
These results indicate that MIK2 may recognize the SCOOP-like sequence derived from Fusarium to induce immunity against Fusarium.
So SCOOP is defined as MIK2 ligand.
The identification of MIK2 ligands will help clarify the multiple roles of MIK2 in plant growth, development and stress response.
Figure 1.
SCOOP12 induces the formation of MIK2-BAK1 complex Figure 2.
Different SCOOP peptides induce MIK2-dependent response Original link: https:// Plant Biotechnology Pbj Exchange In order to more effectively help the vast number of scientific researchers to obtain relevant information, Plant Biotechnology Pbj has established a WeChat group, Plant Biotechnology Journal submissions and document-related questions, public account release content and public account submission questions will be concentrated in the group for answers , And at the same time encourage academic exchanges and collision thinking within the group. In order to ensure a good discussion environment in the group, please add the editor WeChat first, scan the QR code to add, and then we will promptly invite you to join the group.
Tips: When adding the editor WeChat and after joining the group, please be sure to note the school or unit + name, and the PI should be noted at the end, and we will invite you to join the PI group.
