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High uric acid and "three highs" come together, how to choose medicine?
Time of Update: 2021-05-09
Febuxostat can reduce blood uric acid levels, mainly by inhibiting the renin-angiotensin-aldosterone system (RASS) to reduce blood pressure, and can improve the renal function of patients with hypertension and hyperuricemia.
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High uric acid without symptoms is not painful?
Time of Update: 2021-05-09
Image source: 123RF For patients with hyperuricemia without any symptoms of gout, it is recommended to maintain a healthy weight, adopt a low-purine diet combined with a DASH diet to control uric acid and avoid gout or other diseases.
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How long does the new crown vaccine work?
Time of Update: 2021-05-09
In the analysis of adult lymph nodes and spleen, Hib, NM, PP, TT, The frequency of fusion clones of RSV and influenza is higher than that of blood.
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What is the cause and effect of high uric acid and kidney damage?
Time of Update: 2021-05-09
Tang Qi proposed that treatment of hyperuricemia can improve renal function, and divided patients with chronic kidney disease (CKD) into an allopurinol-lowering uric acid treatment group and a placebo control group.
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"The Lancet": There are only 4 steps from "high uric acid" to "tophi"!
Time of Update: 2021-05-09
*It is only for medical professionals to read for reference. Even among people with severe hyperuricemia, less than 50% of people will get gout in 15 years. The prevalence rate of gout in my countr
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Trends in Immunology Editor's Choice: 17 Best Reviews in 2020
Time of Update: 2021-05-09
Looking back at 2021, Trends in Immunology is pleased to launch this collection of papers, introducing the best review articles we have published in the past year to everyone.
These reviews and opinion articles are highly influential, forward-looking and practical.
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The child was caught in the grave at Qingming?
Time of Update: 2021-05-09
Understanding Anti-NMDAR Encephalitis Some time ago during the Qingming holiday, 9-year-old Xiaohuan went back to his hometown with his parents and went to the grave for his deceased grandfather.
So far, Xiao Huan's diagnosis has been clear-it is a disease called "anti-NMDAR encephalitis", which is an autoimmune encephalitis.
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Bone Res | Multi-unit cooperation such as the Army Medical University!
Time of Update: 2021-05-09
The discovery of cartilage formation in the ligaments of AS patients indicates that the pathogenesis of spinal fusion is the process of HO, and explains why anti-inflammatory treatment does not slow the rate of ankylosing response once new bone formation occurs in the soft tissues of the spinal column.
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In addition to carcinogenesis and silicosis, silicon dioxide is also related to rheumatism?
Time of Update: 2021-05-09
This study shows that the level of exposure to SiO2 dust at work is associated with autoimmune rheumatic diseases There is a clear connection, the most obvious being systemic sclerosis and rheumatoid arthritis.
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Systemic lupus erythematosus "increased disease activity 1" increases the risk of kidney damage by 24%!
Time of Update: 2021-05-09
Each increase of 1 unit in the mean SELENA-SLEDAI of patients in the observation period significantly increased the risk of organ damage during the follow-up period by 9% (HR=1.
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Why does gout always strike at night?
Time of Update: 2021-05-08
1. The human body is relatively short of water at night, and uric acid is more likely to deposit.
The body will be in a relatively dehydrated state, blood concentration will increase the concentration of uric acid, crystal precipitation and increase the risk of gout attacks.
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The first IgA nephropathy (IgAN) treatment!
Time of Update: 2021-05-08
com/fda/" target="_blank">FDAIf approved, Nefecon will become the first therapy specifically designed and approved for the treatment of IgAN, with disease correction potential.
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The 5 commonly used rheumatism indicators represent very different meanings!
Time of Update: 2021-05-08
Clinical Significance of ASO After patients diagnosed with hemolytic streptococcal infection, active rheumatic fever, scarlet fever, and erysipelas, ASO increased.
Therefore, if you want to completely diagnose or rule out RA, you can't just look at RF, but combine RF, erythrocyte sedimentation rate (ESR), anti-CCP antibodies and CRP and other indicators and comprehensive consideration of RA clinical response.
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How to apply imaging technology in spondyloarthritis?
Time of Update: 2021-05-08
In order to further understand the specific application of imaging technology in the clinical management of SpA, we are honored to invite Professor Li Guangtao and Professor Deng Xuerong from the Department of Rheumatology and Immunology of Peking University First Hospital to express their views and opinions on this.
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Science Immunology: Renewing the new understanding of the immune response of rheumatoid arthritis
Time of Update: 2021-05-08
In HLA-DR4 transgenic mice, due to selective clonal expansion from pre-immunization procedures, immunization with Fibβ-74cit 69-81 peptide can lead to the tetramerization of HLA-DR4 dicitrulline epitope (Fibβ-74cit 69-81 ) The body exhibits a biased T cell receptor (TCR ) β chain usage of T cells.
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A phase III clinical study (RHBH) of the treatment drug for moderate-to-severe plaque psoriasis in the Chinese population of ezizumab has achieved positive main research results
Time of Update: 2021-05-08
On April 23, 2021, Eli Lilly China announced that the Phase III clinical study (RHBH) evaluating ezizumab for Chinese adults with moderate to severe psoriasis has been successfully completed.
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Re-submitting BLA's regenerative therapy, can it break through the challenge of CMC | Yimai Meng broke the news
Time of Update: 2021-05-08
Recent popular reports from Yimaike ★ Nanjing · Big coffee gathered in May 2021 nucleic acid drug development forum announced schedule ★ May Nanjing 2021 nucleic acid drug development forum is about to open April 29, 2021 / Yimaike news eMedClub News/--Recently, Enzyvant announced that it has resubmitted a biologics license application (BLA) for RVT-802 to the US FDA for the treatment of pediatric congenital athymia (pediatric congenital athymia).
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Lancet: IL-17A/F Nanobody Solomizumab has been successfully treated in Phase II clinical trial of plaque psoriasis
Time of Update: 2021-05-08
Patients aged 18-75 with moderate to severe plaque psoriasis participated in the study and were randomly divided into 6 groups, namely placebo group, 30 mg solovizumab group, 60 mg solovizumab group, Solocizumab 120 mg normal load group, solocizumab 120 mg enhanced load group or secukinumab 300 mg group.
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Nat Commun | Gong Tao/Lei Guanghua jointly develop a new strategy for targeted therapy of rheumatoid arthritis
Time of Update: 2021-05-08
In order to restore the immune balance and bone balance in RA joints, Professor Tao Gong's group from West China School of Pharmacy of Sichuan University and Professor Lei Guanghua's group from Xiangya Hospital of Central South University jointly developed a drug that can accurately deliver drugs and induce targeted joints.
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NEJM: Bimekizumab vs. Adalimumab in the treatment of moderate to severe plaque psoriasis
Time of Update: 2021-05-08
The effect of Bimekizumab in the treatment of moderate to severe plaque psoriasis is due to adalimumab, but the risk of diarrhea and infection is increased.
The effect of Bimekizumab in the treatment of moderate to severe plaque psoriasis is due to adalimumab, but the risk of diarrhea and infection is increased.
