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The European Medicines Agency accepts the marketing authorization application (MAA) of Enfortumab Vedotin
Time of Update: 2021-04-13
MAA's approval is based on the global Phase III EV-301 trial, which evaluated the efficacy of enfortumab vedotin in the treatment of adult patients with locally advanced or metastatic urothelial cancer who have previously received platinum-based chemotherapy and PD-1/L1 inhibitors.
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European Radiology: resting state fMRI machine learning to predict individualized hand movements in patients with PRC cortical tumors
Time of Update: 2021-04-13
The purpose of this study is to evaluate the effectiveness of neural network methods and ICA-based methods in predicting the preoperative motion area mapping of patients with PRC brain tumors using rs-fMRI data.
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2020 transcripts of 4 major listed CAR-T pharmaceutical companies announced
Time of Update: 2021-04-13
2 million in research and development of other pipelines, the overall R&D expenditure has increased by about 43%.
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Br J Cancer: Down-regulation of ITGA6 expression enhances the invasiveness of multiple myeloma and promotes its development into plasma cell leukemia
Time of Update: 2021-04-13
ITGA6 mediates the invasion of MM cellsAll in all, the results of this study show that during the malignant progression of plasma cells, the level of ITGA6 gradually decreases, and the low expression of ITGA6 contributes to the metastasis of myeloma.
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How is metastatic hormone-sensitive prostate cancer treated?
Time of Update: 2021-04-13
Data show that, compared with placebo plus ADT, enzalutamide combined androgen deprivation therapy (ADT) radiographic mHSPC risk patients or death was significantly reduced% 61 (P <0.
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Cell Metab: Creatine promotes tumor metastasis by activating Smad2/3
Time of Update: 2021-04-13
Recently, researchers reported the adverse effects of creatine using an orthotopic mouse model, showing that creatine can promote the metastasis of colorectal cancer and breast cancer , and shorten the survival time of mice .
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Br J Cancer: Meta-analysis shows the correlation between diabetes and cancer risk
Time of Update: 2021-04-13
1038/s41416-021-01347-4">Prevalent diabetes and risk of total, colorectal, prostate and breast cancers in an ageing population: meta-analysis of individual participant data from cohorts of the CHANCES consortium .
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Br J Cancer: Epithelial-mesenchymal transition affects the radiotherapy resistance and cell invasion of oral squamous cell carcinoma
Time of Update: 2021-04-13
The results of this study emphasize the functional significance and complexity of tumor cell remodeling in response to radiotherapy, which is related to the generation of drug resistance and the ability of tumor cells to invade.
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Data from more than 400,000 people confirm that night light may increase the risk of thyroid cancer by 55%!
Time of Update: 2021-04-13
Recently, a study of more than 460,000 participants published in Cancer showed that night light may significantly increase the risk of thyroid cancer, especially in women.
Recently, a study of more than 460,000 participants published in Cancer showed that night light may significantly increase the risk of thyroid cancer, especially in women.
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The domestic cervical cancer vaccine has landed, all you don’t know about it are here
Time of Update: 2021-04-13
More than 90% of women with cervical cancer are accompanied by high-risk HPV infection.
Therefore, as long as it can prevent high-risk HPV virus infection, it can reduce the chance of cervical cancer by 90%.
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BMC Med: The relationship between trans fatty acid intake and breast cancer risk
Time of Update: 2021-04-13
The results of this study support the hypothesis that TFA is related to breast cancer risk, that is, high dietary ITFA intake, especially oleic acid intake, is related to increased breast cancer risk.
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Br J Cancer: Prospective study reveals the causal relationship between gallstone disease and gastrointestinal cancer risk
Time of Update: 2021-04-13
When a meta-analysis of genetic parameter estimates in CKB and UK Biobank (UK Biobank) was performed, it was revealed that there is a causal relationship between GSD and colon cancer , gallbladder and cholangiocarcinoma (GBTC), and total GI cancer.
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Shanghai Cell Therapy Group completes D1 round of nearly 500 million yuan in financing
Time of Update: 2021-04-13
In addition, it is worth mentioning that in 2020, Shanghai Mengchao Tumor Hospital, established by Shanghai Cell Therapy Group with an investment of 800 million yuan, will officially operate and become an affiliated hospital of Shanghai University, becoming a clinical research hospital featuring " immunotherapy +".
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Br J Cancer: Retrospective observational study of neoadjuvant therapy for breast cancer
Time of Update: 2021-04-13
Breast cancerAccording to the ASCO /CAP guidelines for HER2 detection in BC patients , the possible combinations of HER2/CEP17 ratio and HER2 gene copy number were classified into 5 groups.
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Lancet Sub-Journal: In addition to the HPV vaccine, you also need to know this for cervical cancer!
Time of Update: 2021-04-13
For this reason, the results of this study provide new evidence for the genetic susceptibility of cervical cancer, especially PAX8, CLPTM1L and HLA genes, suggesting the effects of apoptosis and interruption of immune function pathways on the occurrence and development of the disease.
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Roche Pharmaceuticals grants Baiyang Pharmaceutical the right to promote two oncology drugs in the Chinese mainland market
Time of Update: 2021-04-13
jointly announced that Roche Pharmaceuticals will combine its two major oncology drug products Xeloda (capecitabine tablets) and Terrol The marketing right of Kai (erlotinib hydrochloride tablets) in mainland China was granted to Baiyang Pharmaceutical.
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Both husband and wife suffer from parotid adenoma, the doctor "same disease but different treatment" customized personalized surgery
Time of Update: 2021-04-13
After carefully analyzing the tumor location, size and imaging examination results of the two, combined with his clinical experience in using endoscopy to assist in the removal of benign tumors of the parotid gland, submandibular gland and neck, Associate Professor Wang Youyuan formulated different surgical plans for the couple.
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Uterine fibroids, Relugolix treatment of uterine fibroids shows potential long-term benefits
Time of Update: 2021-04-13
Pfizer and Myovant Sciences announced that Relugolix combination therapy may have "potential benefits" for the long-term treatment of patients with uterine fibroids.
Juan Camilo Arjona Ferreira, Chief Medical Officer of Myovant Sciences, said: "We are very pleased to see the positive data from the LIBERTY study, which supports the potential benefits of long-term Relugolix combination therapy.
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Nature Sub-Journal: The latest research reveals whether hypoxia is tumor suppression or tumor promotion
Time of Update: 2021-04-13
The results of the study showed that an immediate early transcription response was determined, strongly dependent on the kinase activity of HIF1A and its cofactor CDK8, including indirect inhibition of MYC targets, and was highly conserved among cancer types.
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JCO: HER2 expression in metastatic gastric cancer and its impact on survival
Time of Update: 2021-04-13
Trastuzumab is the only targeted drug approved for the treatment of human epidermal growth factor receptor 2 positive (HER2+) metastatic gastric cancer (mGC).
