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Avasopasem for treatment of severe oral mucositis induced by radiotherapy, the phase III ROMAN trial failed to reach the primary endpoint
Time of Update: 2021-11-02
preventionGalera Therapeutics, a clinical-stage biopharmaceutical company, today announced the results of the avasopasem phase III ROMAN trial, which evaluated avasopasem treatment of severe oral mucositis (SOM) in patients with locally advanced head and neck cancer (HNC) who received standard radiotherapy.
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Science: Gut bacteria can cause prostate cancer growth and treatment resistance
Time of Update: 2021-10-21
found that androgen deprivation in prostate cancer patients and mouse models promoted the proliferation of specific intestinal bacteria that can synthesize androgens, leading to continued tumor growth in mice .
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Gastric Cancer: Triglyceride-glucose index can predict the occurrence of gastric cancer
Time of Update: 2021-08-27
Therefore, this project aims to study the relationship between the triglyceride-glucose (TyG) index and the occurrence of gastric cancer, including precancerous lesions such as dysplasia, atrophic gastritis and intestinal metaplasia .
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Merck's oncology product lineup data presented on ASCO21 highlights major advances in cancer treatment
Time of Update: 2021-06-10
BAVENCIO 's approved indications In the United States, BAVENCIO is suitable for the maintenance treatment of locally advanced or metastatic urothelial carcinoma (UC) patients who have not progressed after first-line platinum-containing chemotherapy .
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Sci. Adv.|Xu Liang/Chen Ye/Huang Yulun collaborated to reveal the active chromatin map of glioblastoma
Time of Update: 2021-05-22
In addition, by analyzing cancer-specific enhancer signals, the study discovered and identified a series of transcription factors, long non-coding RNAs and drug targets (such as MNK2 and BRD4, etc.
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The end result of MSI standardized testing: 4 major guidelines/consensus updated from 2021, talk about the site selection of MSI testing
Time of Update: 2021-05-21
From the four latest editions of the guidelines/consensus above, we can see that the current gold standard method for MSI detection is PCR + capillary electrophoresis, and there are only two site selections, one is NCI's 2B3D Panel, and the other is Promega Panel of 5 single nucleotides.
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Drug K approved for first-line treatment of esophageal cancer
Time of Update: 2021-04-20
*It is only for medical professionals to read. The high ORR of K drug combined with chemotherapy brings unlimited possibilities for operable esophageal cancer immunotherapy. On March 24, 2021, th
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JBC: Controlling cholesterol helps kill lymphoma cells
Time of Update: 2021-03-04
the study looked at lymphoma cells, scientists say the new experimental drug may be effective in other cholesterol-like cancers, such as kidney and ovarian cancer.
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WCLC 2020: Datopotamab deruxtecan and Enhertu show promising clinical activity in patients with advanced non-small cell lung cancer
Time of Update: 2021-02-03
results from the TRTPION-PanTumor01 Phase I trial showed good clinical activity in patients with late-stage or metastasis NSCLC targeting TRAP2.
addition, the results of the DESTINY-Lung01 Phase II clinical trial showed that metastasis NSCLC patients using Enhertu, which targeted HER2, had preliminary evidence of tumor resistance in HER2 over-expression queues.
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Nat Commun: Short H2A histoprotein mutants express and manifest cancer protein properties in cancer
Time of Update: 2021-02-03
B In a variety of cancers, the expression researchers by the species of short H2A sequence and wild H2A cancer protein-related mutations comparative analysis, the researchers found that sH2A protein has similar to the nuclear small body instability associated with the recurrence of cancer gene mutations, that is, with inherent cancer protein characteristics, the most typical sH2A mutation protein is H2A.B.
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Low-dose carpental maintenance therapy for early triple-negative breast cancer can improve the five-year disease-free survival rate
Time of Update: 2021-01-23
main endpoint is a 5-year disease-free life, i.e. from random grouping to the time when the following events first occur: local recurrence, distant metastasis, side-by-side breast cancer, or death for any cause.
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Hepatology|。 Post-liver transplant results in liver cancer patients: Multi-center queue report in the United States
Time of Update: 2021-01-15
same time, the U.S. Organ Procurement and Transplant Network recently approved the priority of liver transplants for HCC patients who exceed Milan's standards and are demoted through local location therapy.
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Dialogue Fosun Pharma Back to Emin: The latest developments in the mRNA new crown vaccine BNT162b2
Time of Update: 2020-12-20
Recently, before the COVID-19 Vaccine/Antibody Research and Development and Industrialization Forum held at Crowne Plaza Hotel in Kunming Center on December 11-12, the Organizing Committee had the honor of interviewing Dr. Hui Aimin, President and Chief Medical Officer of Fosun Pharma Global Research and Development, in advance to talk about the latest development of the mRNA new coronary nucleic acid vaccine BNT162b2, which has attracted much attention in the industry.
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Chinese scholars have revealed the escape mechanism of liver cancer cells in the early stages
Time of Update: 2020-12-07
The Zhao Bin team of Zhejiang University's Institute of Life Sciences, by establishing animal models of early stage liver cancer, captured for the first time the process by which a single liver tumor starting cell evaded the immune system's "hunt-down" and revealed its principles.
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Reveals Chinese complex diseases between intestinal virlobes and complex diseases
Time of Update: 2020-10-17
original title: Westlake University Zheng Weisheng team to reveal the Chinese the relationship between the intestinal bacteria and complex diseases in the human intestine, there is a large group of microorganisms invisible to the naked eye.
