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Breakthrough: 30 ready-made COVID-19 drugs identified using live viruses!
Time of Update: 2020-10-02
!--webeditor:page"--April 27, 2020 / -- Scientists at the University of Sanford Burnham School of Medical Discovery, the University of Hong Kong, the Scripps Research Center, the University of California, San Diego School of Medicine, the Mount Icaine School of Medicine, and the University of California, Los Angeles, have discovered 30 existing drugs that could prevent the replication of the SARS-CoV-2 virus.
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bioRxiv: Redsiway can significantly impair fertility! Chinese scientists have found that Redsyve significantly reduces sperm count and quality in male mice!
Time of Update: 2020-10-02
In this way, researchers from the Department of Reproductive Medicine of Shenzhen Maternal and Child Health Hospital, the Institute of Translational Medicine of Shenzhen Second People's Hospital and the First Affiliated Hospital of Shenzhen University Medical Department conducted a study on the effects of Redsiway on sperm quality and sperm production in mice, and the results of the study were recently published on the preprinted platform bioRxiv, entitled "A preliminary study on the reproductiveity of GS-5734 on male mice".
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Antiviral drugs are as important as vaccines in the fight against coronavirus.
Time of Update: 2020-10-02
means that antiviral drugs that block RNA genome replication may help treat COVID-19 patients.
the presence of similars in the virus genome hinders viral polymerases, which means that viruses cannot replicate their RNA.
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Can suppressing an out-of-control immune response treat COVID-19?
Time of Update: 2020-10-02
Dela Cruz, a lung physician at Yale University School of Medicine who studied COVID-19, said that when infected, the virus appears to replicate in patients, leading to disease and an inflammatory response from the immune system to intruders.
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J Exp Med: Accident! Inhibiting tumor resistance genes weakens the anti-cancer immune response and is not the best way to fight cancer!
Time of Update: 2020-10-02
photo source: J Exp Med (2020) 217 (5) e20191388 Research published recently in The Journal of Test Medicine, entitled "The Journal of Health and function of the MDR1 transporter in Cytoxic T lymphocytes", the study shows that Repeated failures of multidruped resistance gene 1 (MDR1) inhibitors in human cancer trials may be due to the basic function of a previously undiscovered CTLs MDR1 gene.
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bioRxiv: Human lung cell and mouse experiments have confirmed that Redsyvir is highly effective at inhibiting the expression of RNA polymerases in SARS-CoV-2!
Time of Update: 2020-10-02
results were published recently on the preprinted platform bioRxiv under the title "Remdesivir potentlys reseds SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice".
Remdesivir potently res SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.
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bioRxiv: Redsywe can prevent coVID-19 disease progress in monkeys.
Time of Update: 2020-10-02
May 4, 2020 / / -- Early treatment of rhesus monkeys infected with coronavirus SARS-CoV-2 with the antiviral drug Redsyvir can significantly reduce clinical disease and lung damage, scientists at the National Institutes of Health say.
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PNAS: New sperm membrane protein helps mammalian fertilization.
Time of Update: 2020-10-02
Photo Source: Dr Yoshitaka Fujihara, Associate Professor, Institute of Microbiological Diseases, PNAS, and lead author of the study, explained: "Using CRISPR/Cas9-mediated genomic editing techniques, we focused on testicular-specific 4930451I11Rik genes to produce mutations with selective inactivation or 'off' genes to 'knock out' mice.
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A new breakthrough in the Journal of Science! Niic acid can help the immune system fight deadly brain tumors!
Time of Update: 2020-10-02
April 16, 2020 / / -- A new study by members of the CSM School of Medicine (CSM) at the University of Calgary has found that niic acid (often referred to as vitamin B3) is used in combination with chemotherapy to help immune cells attack glioblastoma, a brain tumor, which significantly slows the progression of the disease in mice.
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bioRxiv: Accident! Chemotherapy drugs or a good antidote to the new coronavirus!
Time of Update: 2020-10-02
This is because chemotherapy drugs can increase levels of endogenetic reaction metabolites, such as reactive oxygen and arginine-directed glycodides, methyl acetaldehyde (acetone), and so on, so it is expected to produce selective toxicity to SARS-CoV-2, the relevant research results Recently published on the preprinted platform bioRxiv, entitled "The Files of the SARS-CoV-2 virus to proteotoxicity - opportunity for repurposed processy of COVID-19 infect".
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Shocked! CoVID-19 male mortality rate is 2.5 times higher than female!
Time of Update: 2020-10-02
study, published in frontiers in Public Health, an open-access journal, examined gender differences in COVID-19 patients for the first time.
coVID-19 patients, the researchers confirmed that older people and those with specific underlying diseases tend to have more serious illnesses and are more likely to die.
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biorxiv: Breakthrough! Type I interferon effectively suppresses SARS-CoV-2!
Time of Update: 2020-10-02
Recently, researchers from the Department of Pathology and the Institute of Human Infection and Immunology at the University of Texas School of Medicine published an article entitled "Potent Antiviral Activities of Type I Interferons to SARS-CoV-2 Infection" on the preprinted platform bioRxiv, indicating that SARS-CoV-2 is significantly sensitive to the treatment of recombined human interferon alpha and beta (IFN alpha/beta).
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How should humans respond to an infectious pandemic if vaccines and drugs ultimately fail?
Time of Update: 2020-10-02
non-drug interventions, such as isolation, social isolation, hand washing, and masks and other protective equipment used by health care workers, are saving us.
, however, what we know now about non-drug interventions can be used to protect us from other viruses, and we need to wait again for another new vaccine or drug.
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Shocked! Do blood sugar levels affect a person's susceptible to coronavirus?
Time of Update: 2020-10-02
suggests that a high blood sugar test called hemoglobin A1c -- even for those without diabetes or prediabetes -- could be used as a marker for patients at risk of COVID-19 disease.
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Science: Accident! Exercise can boost endurance through cytokines!
Time of Update: 2020-10-02
, however, endurance training increased network signals of mitochondrial and fatty acid oxidation genes in the control group's muscles, which were lost in mice lacking IL-13.
that the muscles lacking in IL-13 show fatty acid utilization defects after a movement and fail to increase the biological process of mitochondrials after endurance training.
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iScience: Reveals the molecular mechanisms that use cannabinin to suppress colon cancer.
Time of Update: 2020-10-01
September 16, 2020 // -- Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are caused by excessive inflammation of the gastrointestinal tract, which often results in high-risk colorectal cancer; Scientists at the agency have found that a treatment based on THC, a cannabinol-based treatment that inhibits colon cancer in mice, is a cannabinol found in cannabis plants, and that THC can also inhibit colon inflammation to prevent the emergence of early-stage cancers induced by carcinogens.
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Research on spicy wood-reducing sugar, fat-lowering and its active ingredients has been progressed.
Time of Update: 2020-09-19
with alpha-glucosidase and pancreatic lipase as key targets, using affinity ultrafiltration mass spectrometrometrometrometromety (UF-LC/MS) technology, the researchers also screened and identified 11 of the spicy wood leaf extract, 7 with potentially sugar-lowering, fat-lowering active functional ingredients.
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"People's Hero" Zhang Boli: "Wu" courageous hero, rate Chinese medicine retrograde stick.
Time of Update: 2020-09-18
" talked about the first-line medical personnel, unfortunately sacrificed heroes, as well as the contribution of the people of Wuhan, the 70-year-old scholar several times in tears, "under the name, in fact, difficult!" I have stained the light of medical and health care workers all over the country, the light of Chinese medicine." from this national war "epidemic" began, Zhang Boli pushed Chinese medicine to participate in the whole process of the new crown pneumonia treatment.
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8 kinds of medicinal standards 39 kinds of Chinese medicine concote norms public.
Time of Update: 2020-09-18
On September 11, the Gansu Provincial Drug Administration issued two documents, "The Gansu Provincial Drug Administration on mercury and other 8 kinds of Gansu Province Chinese-Tibetan medicinal stand
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A plant-based, high-protein diet may reduce the risk of heart disease.
Time of Update: 2020-09-17
researchers found that a high-protein diet was associated with a reduced risk of death for a variety of causes, but also plant-based proteins were associated with a reduced risk of heart disease, diabetes and stroke.