A new breakthrough in the Journal of Science! Niic acid can help the immune system fight deadly brain tumors!

April 16, 2020 / / -- A new study by members of the CSM School of Medicine (CSM) at the University of Calgary has found that niic acid (often referred to as vitamin B3) is used in combination with chemotherapy to help immune cells attack glioblastoma, a brain tumor, which significantly slows the progression of the disease in mice.
study, published in the journal Science Translational Medicine, found that mice treated with glioblastoma more than tripled their lifespan, from 40 to 150 days.
"It's a remarkable result.
New it's not a therapeutic drug yet, it's a promising advance against this incurable disease," said lead researcher and professor of oncology Atletico, of the Department of Research and Clinical Neuroscience at CSM.
" glioblastoma brain tumor stem cells have been very difficult to treat, so instead of targeting these cells, we are targeting the immune system in the hope that it will help the body attack and destroy stem cells.
" Photo Source: Wee Yong Glioblastoma is the most invasive brain cancer.
, chemotherapy and radiotherapy, most people die within 14 to 16 months of diagnosis.
reason the cancer is so deadly is that it hijacks the immune system, suppresses it and reprograms immune cells to work for tumors.
In this study, researchers found that the use of niic acid alone can prolong a patient's survival, while a combination of tymocyte, a chemotherapy drug commonly used to treat glioblastoma, can significantly prolong a patient's survival because it stimulates and retrains immune cells to stop helping cancer and instead destroy it.
"We can help immune cells do what they are supposed to do, attack and kill cancer cells," said lead author Dr. Susobhan Sarkar.
we screened 1,040 compounds and found that ninic acid has the properties needed to activate immune cells -- especially myelin cells -- and to inhibit the growth of stem cells that initiate brain tumors.
"We're lucky to have THEHR's support," Yong said.
still need approval from Health Canada and the Ethics Committee," he said.
it is important to follow a rigorous treatment plan and conduct clinical trials first, even if the treatment involves two well-known existing treatments.
important is that people don't rush to try adding niic acid themselves, because we need to determine the dose, frequency and length of time for the best clinical outcomes.
" () Reference: Study: Niacin may help immune system battle a deadly tumor brain (2) Susobhan Sarkar et al. Control of brain tumor growth by reactivating myeloid cells with niacin, Science Translational Medicine (2020). DOI: 10.1126/scitranslmed.aay9924.