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Modification of "molecular glue" can develop new anti-tumor drugs
Time of Update: 2021-11-11
"We use biochemistry, structural biology, computational biology and chemical biology to design and optimize molecular glue based on the structure of the complex, and create more effective apoptosis-inducing molecules, which lays the foundation for the development of new tumor therapeutic drugs.
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MDA5-MAVS antiviral pathway activation mechanism revealed
Time of Update: 2021-11-11
This study fills up the gaps in the research on MDA5 pathway activation and signal transduction, and further reveals the immunological function of long-chain, non-anchored K63-polyUb as an endogenous agonist in the cell, and in order to understand the molecular diversity of ubiquitin in anti-RNA The role of viral innate immune signal transduction and regulation provides new clues .
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Scientists develop new strategies for the treatment of viral and bacterial mixed pneumonia
Time of Update: 2021-11-11
This Chinese medicine material science strategy may provide new research and development ideas and safe and effective alternatives for the current clinical treatment of lethal bacterial-virus mixed pneumonia .
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Antibacterial peptide polymer bone cement has made progress in the treatment of chronic osteomyelitis
Time of Update: 2021-11-11
Antibacterial polypeptide polymer bone cement has made progress in the treatment of chronic osteomyelitis Recently, Professor Liu Runhui’s research team from the School of Materials Science and Engineering of East China University of Science and Technology and Professor Lin Haodong’s team from Shanghai First People’s Hospital have prepared PMMA (polymethyl methacrylate) doped with antimicrobial peptide polymers based on host defense peptide simulation.
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DNA redefines human disease
Time of Update: 2021-11-11
Researchers from Osaka University in Japan and Harvard Medical School in the United States conducted GWAS on biological samples from different populations to identify specific genomic loci related to various medical indicators and characteristics .
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New possibilities for diagnosing RNA single-base errors
Time of Update: 2021-11-11
The research group used the target RNA to activate Cas14a1 to trigger the trans-cleavage function to develop the ATCas-RNA analysis platform, which has a good ability to detect pathogenic microorganisms with similar 16s RNA gene sequences .
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PH meter-Why does the PH meter do not display when it is turned on?
Time of Update: 2021-11-11
No display at bootThe cause of the failure: 1) The potential of the LCD screen and the main board connection does not match; 2) The connection between the main board and the LCD screen is in poor cont
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Feet numb and sore?
Time of Update: 2021-11-11
In this study, the researchers looked at the records of all patients diagnosed with small fiber neuropathy in Olmsted County, Minnesota and neighboring areas over a 20-year period .
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This pharmaceutical company, which focuses on small molecule tumor drug therapy, successfully listed on the market!
Time of Update: 2021-11-05
ABSK091 is a potentially highly selective small-molecule pan-FGFR inhibitor, which is being developed for the treatment of various solid tumors and is introduced with authorization from AstraZeneca .
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Within a week, this pharmaceutical company has signed two multi-billion-dollar cooperation projects
Time of Update: 2021-11-04
On October 15, Hansen Pharmaceuticals announced that it has entered into an exclusive license cooperation agreement with Silence Therapeutics plc .
At that time, Hansen Pharmaceuticals will pay an advance payment of US$16 million, while Silence Therapeutics is expected to receive potential milestone payments of up to US$1.
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Focusing on the research and development of a new generation of radiopharmaceuticals, this pharmaceutical company completed over 300 million yuan in financing
Time of Update: 2021-11-04
It can be seen that the capital market highly recognizes the strong nuclear drug innovation and research and development capabilities of Xiantong Pharmaceutical .
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Featured API supplier plans to IPO on GEM: nearly 1.2 billion yuan will be raised for API and other projects
Time of Update: 2021-11-04
According to statistics, in 2019, in terms of China's ibuprofen export sales, Hendy Pharmaceuticals accounted for more than 30%, and it also accounted for nearly 40% in the domestic market.
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Ningbo Bows-Li Wanxiang Attends 2021 Compressed Air Dual-Carbon Energy Saving Summit Forum
Time of Update: 2021-11-04
To this end, the Shanghai Air Standard Compressor Technology Testing Center and the Shanghai International Biological Fermentation Exhibition Organizing Committee jointly organized this summit forum and invited senior experts from related industries to exchange and discuss .
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BeiGene's innovative drugs are speeding up overseas and have been approved for listing in Russia
Time of Update: 2021-11-04
On October 20, BeiGene announced that its innovative drug Baiyueze® (Zebutinib) has been approved by the Russian Ministry of Health for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one treatment in the past .
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This Chinese medicine company changed owners to survive, and Sinopharm Zhaoxiang has taken over the voting rights
Time of Update: 2021-11-03
. In response to the continuous decline in the company’s net profit in recent years, Zixin Pharmaceutical mentioned in its reply to the inquiry letter from the Shenzhen Stock Exchange that it was mainly in the area of proprietary Chinese medicines.
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Buchang Pharmaceutical has started a buy-buy-buy model, and plans to acquire Beijing Siheyuan across the border this time!
Time of Update: 2021-11-03
The announcement shows that this acquisition is to meet the future business development needs of Buchang Pharmaceuticals, promote the smooth implementation of the company's overall strategy, enhance the company's overall operating environment and external image, and realize the plan of "China's Johnson & Johnson, the world's step" .
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Animal-derived drug-resistant genes and resistant bacteria can accumulate in dust for a long time
Time of Update: 2021-11-01
Professor Ying Guangguo's Antibiotic Resistance Research Group, Bai Hong and others from the School of Environment of South China Normal University studied the transmission mode and exposure risk of ARGs and ARBs (especially zoonotic pathogens) transmitted in the atmosphere in chicken farms and dairy farms.
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Calorie restriction can inhibit tumor growth
Time of Update: 2021-11-01
Matthew Vander Heiden of the Massachusetts Institute of Technology and colleagues studied the effects of calorie restriction and ketogenic diet on mouse models of pancreatic cancer and found that only calorie restriction can inhibit tumor growth .
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Blood is not always needed for blood transfusion
Time of Update: 2021-11-01
Recently, a new biochemical model of the human body showed that patients with anemia or low blood oxygen levels can receive effective treatment by transfusing blood substitutes that are easier to obtain .
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Older women are more vulnerable to "heartbreak"
Time of Update: 2021-11-01
"Although the global new coronary pneumonia pandemic has brought many challenges and pressures to women, our research shows that the increase in confirmed cases of broken heart syndrome started long before the outbreak .
