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Plant Cell. A new mechanism for the control of immunity in plant pores.
Time of Update: 2020-07-21
In conclusion, sif2 participates in ABA and flg22 mediated stomatal closure through interaction and phosphorylation with the anion channel slac1 of guard cells, thus playing a key role in stomatal immunity of plants to bacteria.
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There have been "Reynolds phenomenon", is sudden lower limb numbness, urination difficulties, this is the dragonfly?
Time of Update: 2020-07-21
Figure 1 physical examination showed swelling of hands, ulcer of fingertips, patchy brown rash and pigmentation on both lower limbs.
Fig. 2 pathological biopsy of skin rash ▎ immunological indexes are as follows: correct answer: mixed connective tissue disease (MCTD).
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Systemic lupus patients, what are the characteristics of men and women?
Time of Update: 2020-07-21
Is gender related to the clinical manifestations and prognosis of systemic lupus erythematosus?
There is a significant gender difference in incidence.
Comparison of clinical characteristics of male and female patients with systemic lupus erythematosus in child-bearing age.
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Science Back-to-Back . . . Natural immunity or DNA vaccine immunity can provide effective memory immunity protection for rhesus monkey SARS-CoV-2 reinfection.
Time of Update: 2020-07-21
it is important that the specific antibody and cellular immune responses of sars-cov-2 were observed in all rhesus monkeys on the 35th day, and the T cell response of the high-dose group was more intense.
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The immunoasive profile of leukemia predicts the benefits of drug resistance and immunotherapy.
Time of Update: 2020-07-21
By analyzing 442 samples from three groups of children and adults with acute myeloid leukemia (AML), the researchers identified a new immune category for the disease, which can predict the possibility of drug resistance and positive response to immunotherapy.
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From the update of the guidelines, look at the therapeutic status of biologics in systemic lupus.
Time of Update: 2020-07-21
as the first and only biological agent approved for SLE treatment in the world, baileyumab can significantly control disease activity, reduce hormone dosage, reduce organ damage, reduce the risk of serious recurrence, and has good safety.
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Treatment of gout, 7 types of situation hasten to take medication, 3 types of food to eat less! Guide time.
Time of Update: 2020-07-21
(level of evidence: medium) for those who can not achieve Su standard after xoi, uric acid excretion drugs and other interventions, but gout attacks are not frequent (< 2 times / year) and there is no subcutaneous gout stone, it is strongly recommended to continue the current ult treatment scheme instead of converting to peglotase treatment.
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Too cunning, Chinese and American scholars have confirmed that the new crown virus can use the body's immune system, open the door to invasion, enhance infection and transmission capacity.
Time of Update: 2020-07-21
novel coronavirus pneumonia, which is generally confirmed by the two studies, indicates that the new crown virus can enhance its ability of infection and transmission by inducing its receptor ACE2 expression.
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"Guidelines for primary diagnosis and treatment of gout and hyperuric acid (2019)" was published! Guide sharing.
Time of Update: 2020-07-21
Suggestions of antiuricemic drug treatment: ① for gout patients who meet the following clinical conditions, we can start drug uric acid lowering therapy (special note: we need to pay attention to the adverse reactions of uric acid reducing drugs): ➤ gouty arthritis attacks ≥ 2 times / year.
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Immunity . . . The Tsinghua Dongchen team reported on the body fluids and cellular immune responses of patients recovering from new crown pneumonia.
Time of Update: 2020-07-21
using the purified sars-cov-2 N protein (nucleocapsid protein), major protease and s-rbd (spike glycoprotein receptor binding region) expressed and purified in vitro, the researchers detected specific IgM and IgG antibodies against these proteins in the sera of convalescent patients.
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Organ transplantation in the last 60 years of difficulties ushered in important progress! The latest Science finds new immune mechanisms to prevent chronic rejection.
Time of Update: 2020-07-21
experimental results in mice showed that the survival time of transplanted organs such as kidney and heart was prolonged several times by treating immune cells based on this finding.
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ACR's latest gout treatment guide: 7 types of cases hasten to take medication, eat less 3 types of food, 42 detailed recommendations!
Time of Update: 2020-07-21
the guideline has brought 42 detailed recommendations from the aspects of acute gout attack control, daily lowering of uric acid and prevention of attack, lifestyle management, drug use of combined diseases, etc., and focused on the standard standard treatment of uric acid reduction therapy (serum uric acid < 6mg / dl, about 360 μ mol / L).
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Lu Yuanqiang, Zhejiang University, etc.: Lei Gongto's application of immune-mediated inflammatory diseases: research progress and prospects.
Time of Update: 2020-07-21
because Tripterygium wilfordii has significant curative effect on autoimmune diseases and has no side effects of hormones, it has attracted the attention of researchers at home and abroad in recent years, and a large number of studies have begun to explore the potential mechanism of anti-inflammatory and immunosuppression.
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New findings: The interaction of the brain and spleen helps with the production of antibodies.
Time of Update: 2020-07-21
a group of nerve cells in these two regions release adrenocorticotropic hormone, which plays a key role in initiating the body's response to stress.
the researchers pointed out that inhibition or ablation of corticotropin producing neurons in two brain regions could damage the formation of plasma cells after antigen injection.
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The latest: another human umbilical cord-filling stem cell IND to receive the treatment of the medical wheat mammoth explosion.
Time of Update: 2020-07-21
June 6, 2020 / emedclub news / - - according to the official website of the drug evaluation center (CDE) of the State Drug Administration, the application for clinical trial of a new drug of human umbilical cord mesenchymal stem cells for injection by Shenzhen Beike Biotechnology Co., Ltd. was accepted on June 5.
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Nature: Super-magical new immune mechanism! Scientists have discovered for the first time that ordinary cells release exosomes as bait to trap and neutralise the lethal toxin seditoids released by superbugs.
Time of Update: 2020-07-21
(source: med.nyu.edu )Based on previous studies, Cadwell and Torres have known that the pore forming toxin secreted by bacteria will bind with ADAM10 on the cell surface, resulting in cell membrane perforation [5].
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Nat E. Wu Jianxuan and others revealed the immunological causes of the high recurrence rate of urinary tract infections.
Time of Update: 2020-07-21
on May 18, 2020, the soman Abraham research group of Duke University Medical Center published a highly polarized Th2 bladder response to infection promoters epithelial repair at the expense of preventing new infections, which provides a possible immunological explanation for the high recurrence rate of urinary tract infection.
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How does CTD-ILD treat? The 2018 edition of the Expert Consensus is read out.
Time of Update: 2020-07-21
in order to improve doctors' understanding of connective tissue-related ILD, standardize the clinical diagnosis and treatment of ctd-ild in China, advocate early screening, early diagnosis and early intervention, pay attention to patient follow-up and management, and ultimately improve the prognosis and quality of life of ctd-ild patients Based on the international and domestic clinical diagnosis and treatment experience and evidence, the consensus was formulated by experts from multiple disciplines such as science.
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The Nutrition and Health Institute has discovered a new mechanism for TRIM24 in antiviral immunity.
Time of Update: 2020-07-21
On April 23, the international academic journal Journal of empirical medicine published online the research paper "trim24 facilities anti infection through mediating k63 linked traf3 ubiquitation" by Xiao Yichuan, Key Laboratory of tumor and microenvironment, Shanghai Institute of nutrition and health, Chinese Academy of Sciences.
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Blessed by disaster?! Rheumatoid arthritis can reduce the risk of breast cancer. A week of wind and clouds.
Time of Update: 2020-07-21
previous studies have shown that the relative risk of heart failure (HF) in young male SLE patients is the highest [65.2 (35.3-120.5) for 20-24 years old], and the overall trend of absolute risk has also increased.