-
Cell: It's heavy! After more than 30 years of scientists finally found the key cause of food allergies - the body's overactive food quality control system!
Time of Update: 2021-01-27
Medzhitov points out, however, that when parasites are eliminated from developed countries, food allergy rates in the population continue to rise sharply, so the researchers speculate that there may be other environmental factors that affect the body's natural food quality control system and promote the body's immune system to become highly sensitive to specific food allergens.
-
Cell: Revealing the molecular mechanisms that target the antiviral immune response of tumors in triple-negative breast cancer is expected to lead to the development of new individualized cancer therapies
Time of Update: 2021-01-27
January 18, 2021 // -- In a recent study published in the international journal Cell, scientists from baylor School of Medicine and other institutions in the United States revealed therapeutically tar
-
Nat Methods: Scientists have developed a new method that could enable portable PCR sequencers to achieve near-perfect accuracy
Time of Update: 2021-01-27
In this study, researchers developed a special barcode system that, like MiniON devices, can improve the accuracy of long-read DNA sequencing platforms by more than 1,000 times, and when using these barcodes to label targeted molecules, the researchers used standard PCR techniques to amplification or manufacture multiple copies of labeled molecules, as well as sequence the resulting DNA.
-
Nature: reveal the mechanism that causes irritable bowel syndrome
Time of Update: 2021-01-27
and clinical studies by " histamine Boeckxstaens and their team have revealed a mechanism that linkes certain foods to the activation of cells that release histamines, called fat cells, and subsequent pain and discomfort.
some of these diseases, the immune response to food antigens is very local, such as irritable bowel syndrome.
-
Sci Adv: Uncovering a new path β islet and cell inflammation promises to help develop new treatments for type 2 diabetes
Time of Update: 2021-01-27
January 18, 2021 // -- A recent study published in the international journal Science Advances entitled "RIPK3-mediated is conserved β-cell response to ER stress", from Scientists at Vanderburg University and others have discovered a new special pathland that opens up islet β cellular inflammation, a hallmark of type 2 diabetes, that could help develop new targeted therapies for diseases affecting one-tenth of the U.S. population.
-
Chronic spontaneous urticaria (CSU) new drug! Novarma's next-generation IgE antibody ligelizumab is eligible for FDA breakthrough drugs!
Time of Update: 2021-01-27
January 14, 2021 // -- Novartis recently announced that the U.S. Food and Drug Administration (FDA) has granted Ligelizumab (QGE031) breakthrough drug eligibility for the treatment of chronic spontaneous urticaria (CSU) patients who do not respond well to H1 antihistamine therapy.
-
The researchers used organ chip technology to simulate lung damage and immune response caused by new coronavirus infections
Time of Update: 2021-01-27
The study uses organ chip technology to establish a model of human neocycell pneumonia disease based on tissue level, and simulates a series of key pathophysiological processes such as lung barrier dysfunction, immune cell adhesion, inflammatory factor release and endodertic cell damage caused by neo-coronavirus infection, reflecting the pathogen-host interaction in which multicellular complex factors in new coronavirus infection are involved.
-
Nature: New study reveals that COVID-19 lasts longer than typical pneumonia and causes more damage
Time of Update: 2021-01-27
this is the first time scientists have systematically analyzed immune cells in the lungs of patients with COVID-19 and compared them to immune cells in the lungs of patients with pneumonia caused by other viruses or bacteria.
Singer, co-author of the paper and an assistant professor of lung and intensive care medicine at Northwestern University School of Medicine.
-
Cell: Revealing the fine structure of the Wnt-Wntless complex promises to help develop new therapies for a variety of cancers
Time of Update: 2021-01-27
also reveals how fatty acids adsorbed to the Wnt protein are protected by membranes when combined with WLS, and helps explain why subjects such as WLS are so important for the transport of Wnt from the intracellular cell membrane.
-
Cell: Acute itching in eczema patients is associated with environmental allergens
Time of Update: 2021-01-27
in a new study, researchers at the University of Washington's St. Louis School of Medicine and other researchers found that allergens in the environment are often to blame for acute itching episodes in eczema patients, and that this itching usually does not respond to histamines because itching signals are transmitted to the brain through a previously unrecoced pathway that current drugs do not target.
-
Nat Microbiol: Scientists hope to use a combination of phage and antibiotic therapy to treat infections caused by the superbug Bosco!
Time of Update: 2021-01-26
photo source: CC0 Public Domain, researchers studied the superbug, called Acinetobacter baumannii, which accounts for up to 20 percent of infections in intensive care units; researcher Jeremy 'We may be able to use a lot of phages to kill Bacillus baboon, which is resistant to antibiotics, but the bacteria are very clever, and they can quickly become resistant to phages in a way that is resistant to antibiotics, ' says Professor Barr.
-
Front in Oncol: Uncover the molecular mechanisms by which ovarian cancer cells adapt to their surroundings to promote tumor growth
Time of Update: 2021-01-26
January 19, 2021 // -- In a recent study published in the international journal Frontiers in Oncology, scientists from Virginia Tech and others in the United States detailed how ovarian cancer cells a
-
BMJ: A short-term low-carbohydrate diet may be directly related to disease relief in people with type 2 diabetes
Time of Update: 2021-01-26
researchers say most benefits are reduced after 12 months, but clinicians may consider using a short-term, low-carbohydrate diet to manage type 2 diabetes while actively monitoring and adjusting patients' diabetes medications when needed.
-
A new combination therapy may help the immune system better attack cancer!
Time of Update: 2021-01-26
By studying mice, the researchers combined two different techniques, using targeted radionuclide therapy, which transports low-dose cell weakened radiation directly to cancer cells, with immunotherapy, which helps the body's immune system identify and destroy cancer cells.
-
Sci Adv: Scientists have identified EGR1, the "guardian protein" of human macrophage inflammatory enhancers
Time of Update: 2021-01-26
JANUARY 19, 2021 // -- In a recent study published in the international journal Science Advances, scientists from the Westa Institute and others in the United States found that a protein that turns on
-
Genome Res: The circadian rhythm clock may control the function of macrophages
Time of Update: 2021-01-26
January 19, 2021 // -- A detailed database of essential cells of the mammalian immune system suggests that humans may be more resistant to disease than previously thought, relying more on the body's d
-
Read the diagnosis and treatment of acute severe pancreatitis
Time of Update: 2021-01-25
The patient, a 25-year-old woman, was admitted to hospital on July 27 for "bloating, abdominal pain and vomiting for 3 days". patients on July 25 no obvious trigger for the on-abdominal persistent sh
-
Ann Rheum Dis: A study has revealed the 10-year course of early hip osteoarthritis in patients with hip pain
Time of Update: 2021-01-25
10-year follow-up showed that 12 per cent of participants (69 participants) received hip replacement surgery (HR) and the prevalence of hip ROA (Kellgren and Lawrence scores ≥2) increased from 19 per cent to 49 per cent.
-
Nat Commun: Functional characteristics of early immune cells
Time of Update: 2021-01-22
the characteristics of early dedring cells differ from those of mature mice, they still have the ability to trigger an effective immune response.
S. Schraml said: "Our data suggest that by adapting the properties of immunoantigens to the specific abilities of early-childhood degeneration cells, it may improve the effectiveness of vaccination in children.
-
Stroke: Study reveals genetic risk factors for stroke
Time of Update: 2021-01-22
JANUARY 20, 2021 /--- In a recent study, researchers from Geisinger identified common genetic variants as risk factors for stroke, especially in patients over 65.